期刊
FRONTIERS IN IMMUNOLOGY
卷 13, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.965503
关键词
gamma delta T cells; vector-borne diseases (VBDs); host immune response; infection; pathogens
类别
资金
- Anhui Medical University
Vector-borne diseases pose major health threats globally, and γδT cells play a crucial role in regulating host-pathogen interactions and disease progression.
Vector-borne diseases have high morbidity and mortality and are major health threats worldwide. gamma delta T cells represent a small but essential subpopulation of T cells. They reside in most human tissues and exert important functions in both natural and adaptive immune responses. Emerging evidence have shown that the activation and expansion of gamma delta T cells invoked by pathogens play a diversified role in the regulation of host-pathogen interactions and disease progression. A better understanding of such a role for gamma delta T cells may contribute significantly to developing novel preventative and therapeutic strategies. Herein, we summarize recent exciting findings in the field, with a focus on the role of gamma delta T cells in the infection of vector-borne pathogens.
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