相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia
Matthieu Rouland et al.
GUT (2022)
Toll-like receptor-2 gene knockout results in neurobehavioral dysfunctions and multiple brain structural and functional abnormalities in mice
Yuting Hu et al.
BRAIN BEHAVIOR AND IMMUNITY (2021)
The gut-joint axis in rheumatoid arthritis
Mario M. Zaiss et al.
NATURE REVIEWS RHEUMATOLOGY (2021)
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome
Simone Dallari et al.
CELL HOST & MICROBE (2021)
Human gut-associated lymphoid tissues (GALT); diversity, structure, and function
Urs M. Morbe et al.
MUCOSAL IMMUNOLOGY (2021)
Antimicrobial Peptides in Gut Health: A Review
Tao Gong et al.
FRONTIERS IN NUTRITION (2021)
Enteric viruses seize their immunomodulatory niche
Danielle E. Campbell et al.
CELL HOST & MICROBE (2021)
Metagenomic profiling of the pro-inflammatory gut microbiota in ankylosing spondylitis
Chen Zhou et al.
JOURNAL OF AUTOIMMUNITY (2020)
Epithelial Toll-like receptors and their role in gut homeostasis and disease
Juan F. Burgueno et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)
Leaky-gut enhanced lupus progression in the Fc gamma receptor-IIb deficient and pristane-induced mouse models of lupus
Arthid Thim-uam et al.
SCIENTIFIC REPORTS (2020)
Interaction Between the Microbiota, Epithelia, and Immune Cells in the Intestine
Hisako Kayama et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 38 (2020)
Using Diverse Model Systems to Define Intestinal Epithelial Defenses to Enteric Viral Infections
Elisha Segrist et al.
CELL HOST & MICROBE (2020)
Zonulin as a potential putative biomarker of risk for shared type 1 diabetes and celiac disease autoimmunity
Lauren K. Wood Heickman et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2020)
Environmental Exposures and Autoimmune Diseases: Contribution of Gut Microbiome
M. Firoze Khan et al.
FRONTIERS IN IMMUNOLOGY (2020)
Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis
Narges Tajik et al.
NATURE COMMUNICATIONS (2020)
Microbial Influences of Mucosal Immunity in Rheumatoid Arthritis
Timothy M. Wilson et al.
CURRENT RHEUMATOLOGY REPORTS (2020)
The Dual Role of Antimicrobial Peptides in Autoimmunity
Wenjie Liang et al.
FRONTIERS IN IMMUNOLOGY (2020)
Gut Microbiota and Immune System Interactions
Ji Youn Yoo et al.
MICROORGANISMS (2020)
Leaky Gut and Autoimmunity: An Intricate Balance in Individuals Health and the Diseased State
Bilal Ahmad Paray et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Serum zonulin in patients with inflammatory bowel disease: a pilot study
Gian Paolo Caviglia et al.
MINERVA MEDICA (2019)
Modulation of Intestinal Epithelial Permeability by Plasma from Patients with Crohn's Disease in a Three-dimensional Cell Culture Model
Pan Xu et al.
SCIENTIFIC REPORTS (2019)
Gut Microbiota Regulation of T Cells During Inflammation and Autoimmunity
Eric M. Brown et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 37, 2019 (2019)
A Link Between Plasma Microbial Translocation, Microbiome, and Autoantibody Development in First-Degree Relatives of Systemic Lupus Erythematosus Patients
Elizabeth Ogunrinde et al.
ARTHRITIS & RHEUMATOLOGY (2019)
Progress in Mycotoxins Affecting Intestinal Mucosal Barrier Function
Zhihua Ren et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes
Mariana Camila Goncalves Miranda et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2019)
Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes
Chiara Sorini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
How the Interplay Between the Commensal Microbiota, Gut Barrier Integrity, and Mucosal Immunity Regulates Brain Autoimmunity
Martina Antonini et al.
FRONTIERS IN IMMUNOLOGY (2019)
Exploiting the Zonulin Mouse Model to Establish the Role of Primary Impaired Gut Barrier Function on Microbiota Composition and Immune Profiles
Alba Miranda-Ribera et al.
FRONTIERS IN IMMUNOLOGY (2019)
The Contribution of Gut Barrier Changes to Multiple Sclerosis Pathophysiology
Maria Chiara Buscarinu et al.
FRONTIERS IN IMMUNOLOGY (2019)
The microbiome in systemic autoimmune disease: mechanistic insights from recent studies
Carina Dehner et al.
CURRENT OPINION IN RHEUMATOLOGY (2019)
Spatial variations in gut permeability are linked to type 1 diabetes development in non-obese diabetic mice
William C. Joesten et al.
BMJ OPEN DIABETES RESEARCH & CARE (2019)
Self-reactive B cells in the GALT are actively curtailed to prevent gut inflammation
Ashima Shukla et al.
JCI INSIGHT (2019)
Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease
Aaron Buckley et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
The intestinal barrier in multiple sclerosis: implications for pathophysiology and therapeutics
Carlos R. Camara-Lemarroy et al.
BRAIN (2018)
Toll-like receptors in immunity and inflammatory diseases: Past, present, and future
Kumar Vijay
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
Eric C. Martens et al.
NATURE REVIEWS MICROBIOLOGY (2018)
Gut microbiota utilize immunoglobulin A for mucosal colonization
G. P. Donaldson et al.
SCIENCE (2018)
Translocation of a gut pathobiont drives autoimmunity in mice and humans
S. Manfredo Vieira et al.
SCIENCE (2018)
The Intestinal Epithelium: Central Coordinator of Mucosal Immunity
Joannie M. Allaire et al.
TRENDS IN IMMUNOLOGY (2018)
Modulation of Inflammatory Arthritis in Mice by Gut Microbiota Through Mucosal Inflammation and Autoantibody Generation
Widian K. Jubair et al.
ARTHRITIS & RHEUMATOLOGY (2018)
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction
V. Michael Holers et al.
NATURE REVIEWS RHEUMATOLOGY (2018)
IFN-gamma, IL-17A, or zonulin rapidly increase the permeability of the blood-brain and small intestinal epithelial barriers: Relevance for neuro-inflammatory diseases
Mohammed T. Rahman et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
An Insight Into the Intestinal Web of Mucosal Immunity, Microbiota, and Diet in Inflammation
Yu Anne Yap et al.
FRONTIERS IN IMMUNOLOGY (2018)
IgA Function in Relation to the Intestinal Microbiota
Andrew J. Macpherson et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 36 (2018)
Mechanisms regulating intestinal barrier integrity and its pathological implications
Chaithanya Chelakkot et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
The therapeutic applications of antimicrobial peptides (AMPs): a patent review
Hee-Kyoung Kang et al.
JOURNAL OF MICROBIOLOGY (2017)
The intestinal epithelial barrier: a therapeutic target?
Matthew A. Odenwald et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Pathogenesis of ankylosing spondylitis - recent advances and future directions
Vidya Ranganathan et al.
NATURE REVIEWS RHEUMATOLOGY (2017)
Leaky Gut As a Danger Signal for Autoimmune Diseases
Qinghui Mu et al.
FRONTIERS IN IMMUNOLOGY (2017)
Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression
Meghali Nighot et al.
AMERICAN JOURNAL OF PATHOLOGY (2017)
Regulation of inflammation by microbiota interactions with the host
J. Magarian Blander et al.
NATURE IMMUNOLOGY (2017)
Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis
Francesco Ciccia et al.
ANNALS OF THE RHEUMATIC DISEASES (2017)
Can probiotics modulate human disease by impacting intestinal barrier function?
Peter A. Bron et al.
BRITISH JOURNAL OF NUTRITION (2017)
Antimicrobial peptides
Ling-juan Zhang et al.
CURRENT BIOLOGY (2016)
Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice
Ningwen Tai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset
Frederico R. C. Costa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
The microbiota in adaptive immune homeostasis and disease
Kenya Honda et al.
NATURE (2016)
Toll-like receptors and chronic inflammation in rheumatic diseases: new developments
Leo A. B. Joosten et al.
NATURE REVIEWS RHEUMATOLOGY (2016)
Gene, environment, microbiome and mucosal immune tolerance in rheumatoid arthritis
Anca I. Catrina et al.
RHEUMATOLOGY (2016)
Immunological aspects of intestinal mucus and mucins
Malin E. V. Johansson et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota
Jia Sun et al.
IMMUNITY (2015)
Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88
Shuhong Guo et al.
JOURNAL OF IMMUNOLOGY (2015)
SLE: Another Autoimmune Disorder influenced by Microbes and Diet?
Qinghui Mu et al.
FRONTIERS IN IMMUNOLOGY (2015)
Intestinal barrier dysfunction triggered by invasive bacteria
F. Barreau et al.
CURRENT OPINION IN MICROBIOLOGY (2014)
Regulation of the Immune System by the Resident Intestinal Bacteria
Nobuhiko Kamada et al.
GASTROENTEROLOGY (2014)
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
Madhukumar Venkatesh et al.
IMMUNITY (2014)
Intestinal Inflammation and Mucosal Barrier Function
Fermin Sanchez de Medina et al.
INFLAMMATORY BOWEL DISEASES (2014)
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
Lance W. Peterson et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Autoimmune Rheumatic Diseases 3 Immunopathogenic mechanisms of systemic autoimmune disease
Marie Wahren-Herlenius et al.
LANCET (2013)
Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals
Meimei Shan et al.
SCIENCE (2013)
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
BARRIERS AND CHANNELS FORMED BY TIGHT JUNCTION PROTEINS II (2012)
Intestinal Permeability and Its Regulation by Zonulin: Diagnostic and Therapeutic Implications
Alessio Fasano
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2012)
Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides
A. L. Frantz et al.
MUCOSAL IMMUNOLOGY (2012)
Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice
Yan Y. Lam et al.
PLOS ONE (2012)
Importance and regulation of the colonic mucus barrier in a mouse model of colitis
J. Petersson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
Invasive Bacterial Pathogens Exploit TLR-Mediated Downregulation of Tight Junction Components to Facilitate Translocation across the Epithelium
Thomas B. Clarke et al.
CELL HOST & MICROBE (2011)
Altered O-glycosylation Profile of MUC2 Mucin Occurs in Active Ulcerative Colitis and Is Associated with Increased Inflammation
Jessica M. Holmen Larsson et al.
INFLAMMATORY BOWEL DISEASES (2011)
Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer
Alessio Fasano
PHYSIOLOGICAL REVIEWS (2011)
Gut-associated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation
Iurii Koboziev et al.
LYMPHATICS IN THE DIGESTIVE SYSTEM: PHYSIOLOGY, HEALTH, AND DISEASE (2010)
Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice
A. S. Lee et al.
DIABETOLOGIA (2010)
Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of Toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes
Tai-Ping Lee et al.
JOURNAL OF AUTOIMMUNITY (2010)
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
Maria T. Abreu
NATURE REVIEWS IMMUNOLOGY (2010)
Intestinal barrier function: Molecular regulation and disease pathogenesis
Katherine R. Groschwitz et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)
Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
Amit Tripathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Intestinal mucosal barrier function in health and disease
Jerrold R. Turner
NATURE REVIEWS IMMUNOLOGY (2009)
The gut microbiota shapes intestinal immune responses during health and disease
June L. Round et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
E. Cario et al.
GASTROENTEROLOGY (2007)
Increased intestinal permeability precedes clinical onset of type 1 diabetes
E. Bosi et al.
DIABETOLOGIA (2006)
Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives
A Sapone et al.
DIABETES (2006)
Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats
T Watts et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C
E Cario et al.
GASTROENTEROLOGY (2004)