4.8 Review

Thiol Modifications in the Extracellular Space-Key Proteins in Inflammation and Viral Infection

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44

Chiara Giannone et al.

Summary: Antibodies of the IgM class are secreted as planar polymers, with the formation of non-native intra-subunit disulfide bonds playing a key role in the biogenesis of secretory IgM. This unusual assembly pathway is ensured by the engagement of protein disulfide isomerase ERp44, which promotes polymerization and formation of disulfide linkages. This allows secretory polymers to form without disrupting the function of membrane IgM.

EMBO JOURNAL (2022)

Article Biochemistry & Molecular Biology

Protein Disulfide Isomerase A3 Regulates Influenza Neuraminidase Activity and Influenza Burden in the Lung

Nicolas Chamberlain et al.

Summary: The interaction between IAV-NA and PDIA3 is necessary for the activity of NA. Inhibition or ablation of PDIA3 reduces NA activity, viral burden, and inflammatory response. Inhibiting PDIA3 may provide a novel approach for the treatment of influenza.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biochemistry & Molecular Biology

Role of Disulphide Bonds in Membrane Partitioning of a Viral Peptide

Samapan Sikdar et al.

Summary: The study elucidated the role of disulphide bonds in the partitioning mechanism of membrane-active Hepatitis A Virus-2B peptide, showing that the inclusion of disulphide bonds restricts peptide insertion and partitioning, leading to reduced membrane remodelling effects of the viral peptide.

JOURNAL OF MEMBRANE BIOLOGY (2022)

Article Biochemistry & Molecular Biology

Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis

Shuang Zhao et al.

Summary: Endothelial dysfunction is the initial process of atherosclerosis, and SNO-Hsp90 plays an important regulatory role in this process. The study found that SNO-Hsp90 levels increase in atherosclerotic human and rodent arteries as well as in oxLDL-treated ECs. Inhibition of iNOS or transfection with Hsp90 Cys521 mutation plasmid can reduce SNO-Hsp90 levels in oxLDL-cultured ECs. Additionally, SNO-Hsp90 at Cys521 disrupts the interaction between Hsp90 and AHA1, but promotes the association of Hsp90 and CDC37, thereby exacerbating atherosclerosis.

REDOX BIOLOGY (2022)

Article Virology

Protein Disulfide Isomerase A4 Is Involved in Genome Uncoating during Human Astrovirus Cell Entry

Nayeli Aguilar-Hernandez et al.

Summary: In this study, the researchers identified PDIA4 as a binding partner for HAstV-1 and -8 spikes, with the PDI inhibitor 16F16 strongly inhibiting infection by HAstV serotypes 1 and 8. It was also shown that RNA interference of PDIA4 expression selectively blocked HAstV-8 infectivity. These findings suggest that PDIA4 is essential for the uncoating of the viral genome during the cell entry process of HAstV-1 and -8.

VIRUSES-BASEL (2021)

Article Multidisciplinary Sciences

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Yuxian Guo et al.

Summary: Redox-dependent regulation plays a key role in the pathogenesis of acute lung injury, and the study demonstrates that Grx1-regulated S-glutathionylation controls macrophage inflammation and alleviates acute lung injury, revealing a molecular mechanism.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Redox modifications of cysteine residues regulate the cytokine activity of HMGB1

Huan Yang et al.

Summary: The study found that the redox state of HMGB1 can regulate its inflammatory activity by controlling the formation of disulfide bonds, providing a new theoretical basis for the inactivation of HMGB1 during inflammation.

MOLECULAR MEDICINE (2021)

Article Multidisciplinary Sciences

S-nitrosylation-mediated coupling of G-protein alpha-2 with CXCR5 induces Hippo/YAP-dependent diabetes-accelerated atherosclerosis

Meng-Lin Chao et al.

Summary: The study demonstrates that S-nitrosylation of GNAI2 drives the development of atherosclerosis in diabetic patients by coupling with CXCR5 and activating YAP, leading to endothelial inflammation. Additionally, reducing SNO-GNAI2 is an effective strategy for alleviating diabetes-accelerated atherosclerosis.

NATURE COMMUNICATIONS (2021)

Review Mathematical & Computational Biology

Post-translational modifications in proteins: resources, tools and prediction methods

Shahin Ramazi et al.

Summary: Posttranslational modifications (PTMs) involve modifications to amino acid side chains in proteins after biosynthesis, affecting various aspects of protein functions. Disruptions in PTMs can lead to diseases, emphasizing the need for computational methods to predict PTMs. High-throughput experimental methods for PTM discovery are laborious, prompting the exploration of computational tools and databases to advance research in this area.

DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION (2021)

Review Biochemistry & Molecular Biology

Thiol switches in membrane proteins - Extracellular redox regulation in cell biology

Inken Lorenzen et al.

Summary: This article discusses the mechanisms of redox-mediated signal transduction, focusing on extracellular redox signaling and thiol switches. It highlights the importance of secreted redox proteins and thiol switches in the ectodomains of membrane proteins.

BIOLOGICAL CHEMISTRY (2021)

Review Biochemical Research Methods

Decoding Post-Translational Modification Crosstalk With Proteomics

Mario Leutert et al.

Summary: Post-translational modifications (PTMs) play a crucial role in regulating protein functions and diversifying the proteome. PTM crosstalk, the interaction between multiple PTMs on the same or different proteins, has been elucidated through advanced proteomic technologies, mass spectrometry instrumentation, and bioinformatics, providing insights into the functional consequences of these interactions.

MOLECULAR & CELLULAR PROTEOMICS (2021)

Article Biochemistry & Molecular Biology

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal ?-helical lid

Jie Yang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Redox Regulation of STAT1 and STAT3 Signaling

Elena Butturini et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Immunology

Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection

Ryan S. Green et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Review Biochemistry & Molecular Biology

Post-Translational Modifications of Circulating Alpha-1-Antitrypsin Protein

Urszula Lechowicz et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biochemistry & Molecular Biology

STAT1 drives M1 microglia activation and neuroinflammation under hypoxia

Elena Butturini et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2019)

Review Biochemistry & Molecular Biology

S-Nitrosylation: An Emerging Paradigm of Redox Signaling

Veani Fernando et al.

ANTIOXIDANTS (2019)

Article Biochemistry & Molecular Biology

Glutaredoxin 1 up-regulates deglutathionylation of α4 integrin and thereby restricts neutrophil mobilization from bone marrow

Yuanyuan You et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease

David C. Trampert et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)

Article Biology

Mechano-redox control of integrin de-adhesion

Freda Passam et al.

Review Cell Biology

Redox Regulation of Inflammatory Processes Is Enzymatically Controlled

Inken Lorenzen et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Article Biochemistry & Molecular Biology

S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1

Kazushi Okada et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Article Biotechnology & Applied Microbiology

Glutathione and thioredoxin systems contribute to recombinant monoclonal antibody interchain disulfide bond reduction during bioprocessing

Michael W. Handlogten et al.

BIOTECHNOLOGY AND BIOENGINEERING (2017)

Article Biochemistry & Molecular Biology

Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease

Olga Gorelenkova Miller et al.

ANTIOXIDANTS & REDOX SIGNALING (2016)

Article Biochemistry & Molecular Biology

Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry

Naazneen Moolla et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2016)

Review Cell Biology

Oxidative and other posttranslational modifications in extracellular vesicle biology

Katalin Szabo-Taylor et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)

Review Microbiology

Pseudomonas Exotoxin A: optimized by evolution for effective killing

Marta Michalska et al.

FRONTIERS IN MICROBIOLOGY (2015)

Article Biochemical Research Methods

Post-translational structural modifications of immunoglobulin G and their effect on biological activity

Laura K. Hmiel et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2015)

Article Cell Biology

S-nitrosylation of Cofilin-1 Serves as a Novel Pathway for VEGF-Stimulated Endothelial Cell Migration

Hong-Hai Zhang et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition

Jie Jia et al.

Article Biochemistry & Molecular Biology

The Cellular Redox Environment Alters Antigen Presentation

Jonathan A. Trujillo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

Sonia Salzano et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Immunology

IgG subclasses and allotypes: from structure to effector functions

Gestur Vidarsson et al.

FRONTIERS IN IMMUNOLOGY (2014)

Review Biochemistry & Molecular Biology

Glutaredoxins in Thiol/Disulfide Exchange

Christopher Horst Lillig et al.

ANTIOXIDANTS & REDOX SIGNALING (2013)

Article Biochemistry & Molecular Biology

Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120

Kathrin Reiser et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Article Biotechnology & Applied Microbiology

Thioredoxin 1 is responsible for antibody disulfide reduction in CHO cell culture

Kristen L. Koterba et al.

JOURNAL OF BIOTECHNOLOGY (2012)

Article Biochemical Research Methods

Predict and analyze S-nitrosylation modification sites with the mRMR and IFS approaches

Bi-Qing Li et al.

JOURNAL OF PROTEOMICS (2012)

Review Biochemistry & Molecular Biology

The SNO-proteome: causation and classifications

Divya Seth et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Hepatitis C Virus (HCV) Envelope Glycoproteins E1 and E2 Contain Reduced Cysteine Residues Essential for Virus Entry

Johanna Fraser et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Multidisciplinary Sciences

Vertebrate-specific glutaredoxin is essential for brain development

Lars Brautigam et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

Identification of S-Nitrosylated Targets of Thioredoxin Using a Quantitative Proteomic Approach

Moran Benhar et al.

BIOCHEMISTRY (2010)

Article Biotechnology & Applied Microbiology

Protein Disulfide Isomerase Does Not Control Recombinant IgG4 Productivity in Mammalian Cell Lines

N. V. L. Hayes et al.

BIOTECHNOLOGY AND BIOENGINEERING (2010)

Article Biotechnology & Applied Microbiology

Mechanism of Antibody Reduction in Cell Culture Production Processes

Yung-Hsiang Kao et al.

BIOTECHNOLOGY AND BIOENGINEERING (2010)

Article Biochemistry & Molecular Biology

Nitric oxide synthase-2 regulates mitochondrial Hsp60 chaperone function during bacterial peritonitis in mice

Hagir B. Suliman et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Biochemical Research Methods

Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin

Changgong Wu et al.

MOLECULAR & CELLULAR PROTEOMICS (2010)

Article Cell Biology

GAPDH mediates nitrosylation of nuclear proteins

Michael D. Kornberg et al.

NATURE CELL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Thiol-Based Redox Switches in Eukaryotic Proteins

Nicolas Brandes et al.

ANTIOXIDANTS & REDOX SIGNALING (2009)

Article Biochemistry & Molecular Biology

Human glutaredoxin-1 catalyzes the reduction of HIV-1 gp120 and CD4 disulfides and its inhibition reduces HIV-1 replication

Joeri Auwerx et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)

Article Immunology

S-nitrosylated S100A8:: Novel anti-inflammatory properties

Su Yin Lim et al.

JOURNAL OF IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

TRPC channel activation by extracellular thioredoxin

Shang-Zhong Xu et al.

NATURE (2008)

Article Multidisciplinary Sciences

Quantifying changes in the thiol redox proteome upon oxidative stress in vivo

Lars I. Leichert et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

S-Nitrosylation of Surfactant Protein-D Controls Inflammatory Function

Chang-Jiang Guo et al.

PLOS BIOLOGY (2008)

Article Biochemistry & Molecular Biology

NOS2 regulation of NF-κB by S-nitrosylation of p65

Zachary T. Kelleher et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1

Ulla Schwertassek et al.

EMBO JOURNAL (2007)

Article Biochemistry & Molecular Biology

Glutaredoxin regulates nuclear factor κ-B and intercellular adhesion molecule in Muller cells -: Model of diabetic retinopathy

Melissa D. Shelton et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

S-Glutathionylation regulates HDL-associated paraoxonase 1 (PON1) activity

Orit Rozenberg et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

Nitric oxide activates TRP channels by cysteine S-nitrosylation

Takashi Yoshida et al.

NATURE CHEMICAL BIOLOGY (2006)

Article Plant Sciences

Nitric oxide modulates the expression of cell cycle regulatory genes during lateral root formation in tomato

N Correa-Aragunde et al.

JOURNAL OF EXPERIMENTAL BOTANY (2006)

Article Biochemistry & Molecular Biology

A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons

A Riccio et al.

MOLECULAR CELL (2006)

Review Biochemical Research Methods

Analysis of posttranslational modifications of proteins by tandem mass spectrometry

Martin R. Larsen et al.

BIOTECHNIQUES (2006)

Article Biochemistry & Molecular Biology

Amyloid-β induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease

RC Cumming et al.

FASEB JOURNAL (2005)

Article Multidisciplinary Sciences

S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities

A Martínez-Ruiz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Immunology

Autoantibodies unmasked by redox reactions

JA McIntyre et al.

JOURNAL OF AUTOIMMUNITY (2005)

Article Immunology

RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages

R Kokkola et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2005)

Article Biochemistry & Molecular Biology

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

JS Park et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

S-nitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity

K Ravi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

CJ Lee et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

Article Multidisciplinary Sciences

Nitric oxide represses inhibitory kB kinase through S-nitrosylation

NL Reynaert et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

S-glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

T Adachi et al.

NATURE MEDICINE (2004)

Article Multidisciplinary Sciences

Redox regulation of surface protein thiols:: Identification of integrin α-4 as a molecular target by using redox proteomics

T Laragione et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems

S Casagrande et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Cathepsin B stability, but not activity, is affected in cysteine:cystine redox buffers

CS Pillay et al.

BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Novel signal transduction pathway utilized by extracellular HSP70 -: Role of Toll-like receptor (TLR) 2 AND TLR4

A Asea et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes

M Fratelli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Review Immunology

IgG4 breaking the rules

RC Aalberse et al.

IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Inhibition of NF-κB by S-nitrosylation

HE Marshall et al.

BIOCHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Mass spectrometry unravels disulfide bond formation as the mechanism that activates a molecular chaperone

S Barbirz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)