4.8 Article

N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Cryo-EM structures of Toll-like receptors in complex with UNC93B1

Hanako Ishida et al.

Summary: Nucleic acid-sensing Toll-like receptors (TLRs) play a crucial role in innate immunity by recognizing foreign DNA and RNA. The interaction between TLRs and UNC93B1 appears to be essential for immune response regulation, with structural details providing insights for potential therapies against autoimmune diseases. However, further research is needed to fully understand the mechanisms involved.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)

Article Multidisciplinary Sciences

Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-γ

Alison G. Stanbery et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Biochemistry & Molecular Biology

Toll-like Receptors and the Control of Immunity

Katherine A. Fitzgerald et al.

Article Multidisciplinary Sciences

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang et al.

SCIENCE (2020)

Review Cell Biology

Endolysosomal compartments as platforms for orchestrating innate immune and metabolic sensors

Kensuke Miyake et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2019)

Article Multidisciplinary Sciences

UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity

Olivia Majer et al.

NATURE (2019)

Article Multidisciplinary Sciences

Release from UNC93B1 reinforces the compartmentalized activation of select TLRs

Olivia Majer et al.

NATURE (2019)

Review Immunology

Nucleic acid-sensing TLRs: trafficking and regulation

Olivia Majer et al.

CURRENT OPINION IN IMMUNOLOGY (2017)

Article Multidisciplinary Sciences

Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

Umeharu Ohto et al.

NATURE (2015)

Review Cell Biology

N-linked sugar-regulated protein folding and quality control in the ER

Abla Tannous et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)

Article Multidisciplinary Sciences

UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

Ji-Won Huh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Physiology

Disruption of N- linked glycosylation promotes proteasomal degradation of the human ATP- binding cassette transporter ABCA3

Michael F. Beers et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)

Article Biochemistry & Molecular Biology

UNC93B1 Is Essential for TLR11 Activation and IL-12-dependent Host Resistance to Toxoplasma gondii

Reed Pifer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi et al.

Review Biochemistry & Molecular Biology

Protein N-glycosylation, protein folding, and protein quality control

Juergen Roth et al.

MOLECULES AND CELLS (2010)

Review Biochemistry & Molecular Biology

Glycoprotein folding, quality control and ER-associated degradation

Gerardo Z. Lederkremer

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

Article Multidisciplinary Sciences

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

You-Me Kim et al.

NATURE (2008)

Article Multidisciplinary Sciences

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

Sarah E. Ewald et al.

NATURE (2008)

Article Multidisciplinary Sciences

Cathepsin K-dependent Toll-like receptor 9 signaling revealed in experimental arthritis

Masataka Asagiri et al.

SCIENCE (2008)

Article Multidisciplinary Sciences

Herpes simplex virus encephalitis in human UNC-93B deficiency

Armanda Casrouge et al.

SCIENCE (2006)

Review Biochemistry & Molecular Biology

N-linked oligosaccharides as outfitters for glycoprotein folding, form and function

N Mitra et al.

TRENDS IN BIOCHEMICAL SCIENCES (2006)

Article Biochemistry & Molecular Biology

MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor

JD Correia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)