4.6 Article

A Resveratrol Phenylacetamide Derivative Perturbs the Cytoskeleton Dynamics Interfering with the Migration Potential in Breast Cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Resveratrol, a Molecule with Anti-Inflammatory and Anti-Cancer Activities: Natural Product to Chemical Synthesis

Sunil Kumar et al.

Summary: Resveratrol, a natural polyphenol compound with anti-inflammatory, cytoprotective, and antineoplastic activities, is widely distributed in plants. Literature survey reveals various studies on chemical synthesis and pharmacological activities related to resveratrol. Research on the structure-activity relationship and synthesis pathways of resveratrol is crucial for future drug development.

CURRENT MEDICINAL CHEMISTRY (2021)

Article Biochemistry & Molecular Biology

A Phenylacetamide Resveratrol Derivative Exerts Inhibitory Effects on Breast Cancer Cell Growth

Adele Chimento et al.

Summary: The study evaluated the antiproliferative and anti-inflammatory activity of phenylacetamide resveratrol derivatives in cancer cell lines, with derivative 2 showing the highest bioavailability and anti-tumor activity, especially against breast cancer cells. The derivatives, particularly derivative 2, inhibited NO and ROS synthesis and PGE2 secretion, induced cell cycle arrest and apoptotic cell death in breast cancer cell lines, highlighting their potential as promising tools for developing new and more bioavailable derivatives for breast cancer treatment.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Oncology

Resveratrol and Its Analogs: Potent Agents to Reverse Epithelial-to-Mesenchymal Transition in Tumors

Kaibo Guo et al.

Summary: Resveratrol and its analogs can reverse EMT through diverse mechanisms, inhibit tumor invasion and migration, potentially serving as novel anti-tumor agents. They can also reverse chemoresistance and improve the antiproliferative effects of conventional treatments.

FRONTIERS IN ONCOLOGY (2021)

Article Multidisciplinary Sciences

Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling

Elena E. Grintsevich et al.

Summary: Cellular events require the spatiotemporal interplay between actin assembly and disassembly. Profilin and Mical combine to impair F-actin assembly and promote F-actin disassembly, while simultaneously facilitating cellular remodeling and plasticity.Actin-based structures in cells and tissues are built and maintained through a poorly understood balance between assembly and disassembly.

NATURE COMMUNICATIONS (2021)

Article Chemistry, Multidisciplinary

N-Heterocyclic Carbene-Gold(I) Complexes Targeting Actin Polymerization

Domenico Iacopetta et al.

Summary: Transition metal complexes, particularly NHC-gold complexes, are being extensively studied for their wide range of biological targets, including their role in regulating cell cytoskeleton organization. Two such complexes, AuL4 and AuL7, have been shown to inhibit actin polymerization, contributing to the development of more effective and safer cancer treatments.

APPLIED SCIENCES-BASEL (2021)

Review Pharmacology & Pharmacy

Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence

Shian-Ren Lin et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Review Genetics & Heredity

Molecular profiling for precision cancer therapies

Eoghan R. Malone et al.

GENOME MEDICINE (2020)

Article Multidisciplinary Sciences

Mechanism of actin N-terminal acetylation

Grzegorz Rebowski et al.

SCIENCE ADVANCES (2020)

Article Biochemistry & Molecular Biology

Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells

Domenico Iacopetta et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Pharmacology & Pharmacy

Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

Barbara Pinto et al.

PHARMACEUTICS (2020)

Article Cell Biology

In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis

Jordi Pijuan et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)

Article Oncology

Innovative approaches for cancer treatment: current perspectives and new challenges

Carlotta Pucci et al.

ECANCERMEDICALSCIENCE (2019)

Review Pharmacology & Pharmacy

Molecular targeted therapy: Treating cancer with specificity

Yeuan Ting Lee et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

Review Cell Biology

Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton

Michel O. Steinmetz et al.

TRENDS IN CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Latrunculin A Accelerates Actin Filament Depolymerization in Addition to Sequestering Actin Monomers

Ikuko Fujiwara et al.

CURRENT BIOLOGY (2018)

Review Biochemistry & Molecular Biology

The Role of Resveratrol in Cancer Therapy

Jeong-Hyeon Ko et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Chemistry, Medicinal

N-heterocyclic carbene complexes of silver and gold as novel tools against breast cancer progression

Carmela Saturnino et al.

FUTURE MEDICINAL CHEMISTRY (2016)

Review Chemistry, Medicinal

Resveratrol and Its Analogs as Antitumoral Agents for Breast Cancer Treatment

Adele Chimento et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2016)

Review Pharmacology & Pharmacy

Three-dimensional culture systems in cancer research: Focus on tumor spheroid model

Sritama Nath et al.

PHARMACOLOGY & THERAPEUTICS (2016)

Article Multidisciplinary Sciences

A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells

Elizabeth Thomas et al.

SCIENTIFIC REPORTS (2016)

Review Chemistry, Medicinal

(6-Bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (Carbhydraz) Acts as a GPER Agonist in Breast Cancer Cells

Maria Stefania Sinicropi et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)

Article Oncology

Spherical Cancer Models in Tumor Biology

Louis-Bastien Weiswald et al.

NEOPLASIA (2015)

Article Biochemistry & Molecular Biology

Recent Advances in the Rationale Design of GPER Ligands

C. Rosano et al.

CURRENT MEDICINAL CHEMISTRY (2015)

Article Cell Biology

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling

Maria Francesca Santolla et al.

CELLULAR SIGNALLING (2014)

Article Chemistry, Medicinal

Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines

Marina Sala et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Cell Biology

Directed cell invasion and migration during metastasis

Jose Javier Bravo-Cordero et al.

CURRENT OPINION IN CELL BIOLOGY (2012)

Article Oncology

A Detailed Mammosphere Assay Protocol for the Quantification of Breast Stem Cell Activity

Frances L. Shaw et al.

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2012)

Article Physiology

Cell Migration

Xavier Trepat et al.

COMPREHENSIVE PHYSIOLOGY (2012)

Article Biochemistry & Molecular Biology

The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster

Domenico Iacopetta et al.

FEBS JOURNAL (2010)

Review Oncology

EMT, the cytoskeleton, and cancer cell invasion

Mahmut Yilmaz et al.

CANCER AND METASTASIS REVIEWS (2009)

Article Chemistry, Multidisciplinary

AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility

Garrett M. Morris et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Chemistry, Multidisciplinary

UCSF chimera - A visualization system for exploratory research and analysis

EF Pettersen et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)