☆ 4.7 Article

Identification of molecular patterns and prognostic models of epithelial-mesenchymal transition- and immune-combined index in the gastric cancer

FRONTIERS IN PHARMACOLOGY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Biochemistry & Molecular Biology

Advances in clinical immunotherapy for gastric cancer

Kexin Li et al.

Summary: Gastric cancer is a highly malignant cancer with increasing incidence worldwide, ranking among the top five malignant tumors in terms of incidence and mortality. Immunotherapy, as a breakthrough in cancer treatment, has shown to be effective in gastric cancer treatment, especially when used in combination with other modalities.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)

添加到收藏夹

Review Chemistry, Medicinal

Understanding the tumor microenvironment for effective immunotherapy

Habib Sadeghi Rad et al.

Summary: Advances in immunotherapy have provided durable and long-term benefits for certain patients with solid tumors, with a key focus on understanding the immune landscape of the tumor microenvironment to develop effective immunotherapeutic strategies.

MEDICINAL RESEARCH REVIEWS (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Review Oncology

PD-L1, TMB, MSI, and Other Predictors of Response to Immune Checkpoint Inhibitors in Biliary Tract Cancer

Alessandro Rizzo et al.

Summary: ICIs have revolutionized the treatment landscape for several malignancies, but their efficacy in biliary tract cancer remains controversial. The lack of reliable predictive biomarkers presents a significant challenge in identifying responders to immunotherapy in this setting.

CANCERS (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Development of epithelial-mesenchymal transition-related lncRNA signature for predicting survival and immune microenvironment in pancreatic cancerwithexperiment validation

Yong Gao et al.

Summary: This study identified the important role of EMT-related LncRNAs in pancreatic cancer and established an eleven LncRNAs signature with potential clinical prognostic value, which could serve as an independent prognostic factor.

BIOENGINEERED (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Tumor-Associated Macrophages and Inflammatory Microenvironment in Gastric Cancer: Novel Translational Implications

Karim Rihawi et al.

Summary: Gastric cancer is the fifth most commonly diagnosed cancer worldwide, with poor prognosis in advanced stage patients despite improvements in treatment. Research efforts have focused on identifying novel therapeutic targets, with the tumor microenvironment emerging as a potential target. Various agents and strategies targeting the TME are currently being evaluated in preclinical and clinical studies.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Gastric Cancer: Advances in Carcinogenesis Research and New Therapeutic Strategies

Lornella Seeneevassen et al.

Summary: Gastric cancer poses a significant global health issue due to its high incidence, poor prognosis, and cellular and molecular heterogeneity. Recent scientific advances have focused on understanding the different factors involved in gastric carcinogenesis, such as Helicobacter pylori, cancer stem cells, tumor microenvironment, and microbiota. Additionally, research has explored new potential biomarkers and emerging therapeutic strategies, including targeting cancer stem cells and immunotherapy, to combat cancer relapse, metastasis, and poor prognosis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Article Oncology

Exploration of Lipid Metabolism in Gastric Cancer: A Novel Prognostic Genes Expression Profile

Zhen Xiong et al.

Summary: This study found that higher expression levels of AKR1B1, PLD1, and UGT8 genes were associated with worse prognosis in GC patients, while AGPAT3 gene was associated with better prognosis. A gene expression profile consisting of AGPAT3, AKR1B1, PLD1, and UGT8 was developed, which stratified patients into three groups with significant overall survival differences. The profile was successfully validated in an independent cohort and performed well in an immunohistochemical cohort. Additionally, alterations in lipid metabolism were observed in GC, with upregulation of ether lipid metabolism, glycerophospholipid metabolism, and glycerolipid metabolism, as well as downregulation of fatty acid beta-oxidation and other lipid peroxidation processes.

FRONTIERS IN ONCOLOGY (2021)

添加到收藏夹

Article Gastroenterology & Hepatology

The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease study 2017

Arash Etemadi et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

添加到收藏夹

Review Oncology

Tumor microenvironment in gastric cancers

Yukiko Oya et al.

CANCER SCIENCE (2020)

添加到收藏夹

Review Cell Biology

Role of aldo-keto reductase family 1 member B1 (AKR1B1) in the cancer process and its therapeutic potential

Reza Khayami et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

添加到收藏夹

Review Immunology

Tumor-Associated Macrophages in Tumor Immunity

Yueyun Pan et al.

FRONTIERS IN IMMUNOLOGY (2020)

添加到收藏夹

Review Oncology

Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors

Dan Sha et al.

CANCER DISCOVERY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Progress in research on paclitaxel and tumor immunotherapy

Linyan Zhu et al.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2019)

添加到收藏夹

Review Oncology

Immunotherapy in advanced gastric cancer, is it the future?

C. Coutzac et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2019)

添加到收藏夹

Review Cell Biology

New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer

Anushka Dongre et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

添加到收藏夹

Review Cell Biology

EMT Transition States during Tumor Progression and Metastasis

Ievgenia Pastushenko et al.

TRENDS IN CELL BIOLOGY (2019)

添加到收藏夹

Review Immunology

The opposing roles of CD4+ T cells in anti-tumour immunity

Tomasz Ahrends et al.

IMMUNOLOGY (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

Peng Jiang et al.

NATURE MEDICINE (2018)

添加到收藏夹

Article Oncology

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

Xiongyan Wu et al.

ONCOTARGET (2017)

添加到收藏夹

Article Oncology

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

Darshan S. Chandrashekar et al.

NEOPLASIA (2017)

添加到收藏夹

Article Biochemical Research Methods

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman et al.

NATURE METHODS (2015)

添加到收藏夹

Article Oncology

Does surgery have a role in managing incurable gastric cancer?

Sri G. Thrumurthy et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

添加到收藏夹

Article Oncology

How to build and interpret a nomogram for cancer prognosis

Alexia Iasonos et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

添加到收藏夹

Review Cell Biology

MHC class I antigens, immune surveillance, and tumor immune escape

A Garcia-Lora et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2003)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.