☆ 4.6 Review

Chinese Herbal Medicine for Functional Dyspepsia With Psychological Disorders: A Systematic Review and Meta-Analysis

FRONTIERS IN NEUROSCIENCE (2022)

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Summary: This study evaluated the comparative effectiveness of herbal medicine formulae for functional dyspepsia through a network meta-analysis. Findings suggest that Xiao Yao Pill and Modified Ban Xia Xie Xin Decoction may have beneficial effects in alleviating global symptoms, with no serious adverse events reported. Further trials are needed to assess the comparative effectiveness of these formulae.

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Summary: This study evaluated the factors associated with changes in functional dyspepsia (FD) symptom severity. The results showed that improvement in anxiety, lower baseline sleep disturbance, absence of irritable bowel syndrome (IBS), and higher baseline FD severity were associated with improvement in FD symptom severity.

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Summary: The therapeutic potential and challenges associated with the adoption of herbal medicines in functional dyspepsia were evaluated, with findings that herbal medicines often comprise a combination of herbs with multiple pharmacological effects but face concerns such as lack of rigorous assessments and quality control. A quality framework for evaluating herbal medicines was provided.

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Chinese herbal medicine for functional dyspepsia: a network meta-analysis of prokinetic-controlled randomised trials

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Summary: This study conducted a network meta-analysis to evaluate the effectiveness of Chinese herbal medicine (CHM) as a substitute for prokinetics in treating functional dyspepsia (FD) in Asia. The results suggest that Modified Zhi Zhu Decoction and Xiao Pi Kuan Wei Decoction may be considered as alternative treatments for patients unresponsive to prokinetics, with a potential for alleviating symptoms without serious adverse events. Further confirmatory trials are recommended to investigate their comparative effectiveness against prokinetics.

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Association of Functional Dyspepsia with Depression and Anxiety: A Systematic Review

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Summary: The study revealed a significant association between functional dyspepsia and depression/anxiety, leading to more serious symptoms and prolonged recovery time for patients, requiring increased medical resources. Gender differences were observed in the psychological links among male and female FD patients, with higher prevalence of depression and anxiety symptoms in refractory FD patients compared to non-refractory FD and healthy individuals.

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Benefit of small dose antidepressants for functional dyspepsia Experience from a tertiary center in eastern China

Liang Luo et al.

MEDICINE (2019)

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Rikkunshito simultaneously improves dyspepsia correlated with anxiety in patients with functional dyspepsia: A randomized clinical trial (the DREAM study)

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WORLD JOURNAL OF GASTROENTEROLOGY (2014)

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Clinical and psychological assessment on Xinwei decoction for treating functional dyspepsia accompanied with depression and anxiety

L Zhao et al.

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