Protocol for randomized controlled trial to evaluate the safety and feasibility of a novel helmet to deliver transcranial light emitting diodes photobiomodulation therapy to patients with Parkinson's disease

Article Surgery

Web Crawling and mRNA Sequencing Analyze Mechanisms of Photobiomodulation

Hao Wu et al.

Summary: By analyzing genes and pathways, we elucidated the mechanisms of photobiomodulation and demonstrated the anti-inflammatory effect of 630 nm LED red light.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2022)

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Review Surgery

Evaluation of Gender Differences in Response to Photobiomodulation Therapy, Including Laser Acupuncture: A Narrative Review and Implication to Precision Medicine

Ann Liebert et al.

Summary: Gender plays a significant role in the response to photobiomodulation therapy, with studies showing gender differences in treatment outcomes. Understanding these gender differences is crucial for the development of precision medicine-based strategies in PBM therapy. Further research is needed to determine optimal treatment doses and parameters tailored to different genders.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2022)

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Article Optics

Effects of stimulating frequency of NIR LEDs light irradiation on forehead as quantified by EEG measurements

Liuye Yao et al.

Summary: The study found that different frequencies of near-infrared light can affect brain activity, with higher frequencies leading to an increase in alpha waves, a decrease in theta waves, and more distinct brain activities in the stimulated areas. The results suggest that near-infrared LED light may have a positive effect on modulating brain activity.

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES (2021)

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Article Neurosciences

Does photobiomodulation influence the resting-state brain networks in young human subjects?

Hala El Khoury et al.

Summary: The study found that transcranial photobiomodulation had no significant effect on the four major resting-state brain networks in normal young subjects. The impact of photobiomodulation only becomes clearer after alterations in brain circuitry due to factors such as pathology, aging, or engagement in specific tasks.

EXPERIMENTAL BRAIN RESEARCH (2021)

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Article Clinical Neurology

Improvements in clinical signs of Parkinson's disease using photobiomodulation: a prospective proof-of-concept study

Ann Liebert et al.

Summary: Photobiomodulation (PBM) showed significant improvements in clinical signs of Parkinson's disease (PD) over a 12-week treatment period, with effects lasting up to one year. The treatment was safe with no observed side effects, indicating it may be an effective therapy option for PD patients.

BMC NEUROLOGY (2021)

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Article Geriatrics & Gerontology

Transcranial Near Infrared Light Stimulations Improve Cognition in Patients with Dementia

Damir Nizamutdinov et al.

Summary: The study examined the safety and therapeutic benefits of transcranial near-infrared (tNIR) light stimulations in treating dementia. The active treatment group showed improvements in cognitive functions, sleep quality, and mood, suggesting potential benefits of tNIR light therapy for dementia patients. This study supports the need for further trials focusing on alleviating caregivers' burden in dementia treatment.

AGING AND DISEASE (2021)

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Article Clinical Neurology

Cognitive function in men with non-motor features of Parkinson's disease

Mario H. Flores-Torres et al.

Summary: The study suggests that individuals with non-motor features suggestive of prodromal PD, particularly when multiple features are present, commonly experience cognitive impairment.

BMJ NEUROLOGY OPEN (2021)

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Review Geriatrics & Gerontology

Strategies for the Treatment of Parkinson's Disease: Beyond Dopamine

Alexandre Iarkov et al.

FRONTIERS IN AGING NEUROSCIENCE (2020)

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Editorial Material Neurosciences

Implementation of Telemedicine for Urgent and Ongoing Healthcare for Patients with Parkinson's Disease During the COVID-19 Pandemic: New Expectations for the Future

Esther Cubo et al.

JOURNAL OF PARKINSONS DISEASE (2020)

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Review Clinical Neurology

Cognition Deficits in Parkinson's Disease: Mechanisms and Treatment

Congcong Fang et al.

PARKINSONS DISEASE (2020)

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Review Medicine, General & Internal

Photobiomodulation-Underlying Mechanism and Clinical Applications

Claudia Dompe et al.

JOURNAL OF CLINICAL MEDICINE (2020)

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Letter Neurosciences

Remote Administration of the MDS-UPDRS in the Time of COVID-19 and Beyond

Ruth B. Schneider et al.

JOURNAL OF PARKINSONS DISEASE (2020)

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Article Medicine, General & Internal

Effect of Transcranial Low-Level Light Therapy vs Sham Therapy Among Patients With Moderate Traumatic Brain Injury A Randomized Clinical Trial

Maria Gabriela Figueiro Longo et al.

JAMA NETWORK OPEN (2020)

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Article Engineering, Biomedical

Transcranial near-infrared photobiomodulation could modulate brain electrophysiological features and attentional performance in healthy young adults

Ali Jahan et al.

LASERS IN MEDICAL SCIENCE (2019)

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Review Medicine, General & Internal

Updates and advances in the treatment of Parkinson disease

Michael W. Hayes et al.

MEDICAL JOURNAL OF AUSTRALIA (2019)

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Article Multidisciplinary Sciences

Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study

Reza Zomorrodi et al.

SCIENTIFIC REPORTS (2019)

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Review Surgery

Penetration Profiles of Visible and Near-Infrared Lasers and Light-Emitting Diode Light Through the Head Tissues in Animal and Human Species: A Review of Literature

Farzad Salehpour et al.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2019)

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Article Surgery

Reported Side Effects, Weight and Blood Pressure, After Repeated Sessions of Transcranial Photobiomodulation

Paolo Cassano et al.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2019)

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Article Surgery

Treatment of Neurodegeneration: Integrating Photobiomodulation and Neurofeedback in Alzheimer's Dementia and Parkinson's: A Review

Marvin H. Berman et al.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2019)

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Article Surgery

Transcranial Photobiomodulation with Near-Infrared Light for Generalized Anxiety Disorder: A Pilot Study

Marco Maiello et al.

PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY (2019)

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Correction Biochemistry & Molecular Biology

Photobiomodulation: lasers vs. light emitting diodes? (vol 17, pg 1003, 2018)

Vladimir Heiskanen et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2019)

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Review Biochemistry & Molecular Biology

Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation

Michael R. Hamblin

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2018)

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Article Engineering, Biomedical

Beneficial neurocognitive effects of transcranial laser in older adults

Enrique Vargas et al.

LASERS IN MEDICAL SCIENCE (2017)

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Article Surgery

Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report

Anita E. Saltmarche et al.

PHOTOMEDICINE AND LASER SURGERY (2017)

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Article Neurosciences

Remotely Assessing Symptoms of Parkinson's Disease Using Videoconferencing: A Feasibility Study

Tereza Stillerova et al.

NEUROLOGY RESEARCH INTERNATIONAL (2016)

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Correction Dermatology

Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue (Retraction of vol 47, pg 312, 2015)

Clark E. Tedford et al.

LASERS IN SURGERY AND MEDICINE (2015)

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Review Clinical Neurology

Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?

Theodore A. Henderson et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2015)

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Article Multidisciplinary Sciences

Standardized Handwriting to Assess Bradykinesia, Micrographia and Tremor in Parkinson's Disease

Esther J. Smits et al.

PLOS ONE (2014)

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Article Neurosciences

The Role of the Trigeminal Sensory Nuclear Complex in the Pathophysiology of Craniocervical Dystonia

Lynley Bradnam et al.

JOURNAL OF NEUROSCIENCE (2013)

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Article Clinical Neurology

Potential reliability and validity of a modified version of the Unified Parkinson's Disease Rating Scale that could be administered remotely

Amir Abdolahi et al.

PARKINSONISM & RELATED DISORDERS (2013)

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Article Health Care Sciences & Services

The size of a pilot study for a clinical trial should be calculated in relation to considerations of precision and efficiency

Julius Sim et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2012)

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Article Multidisciplinary Sciences

Transcranial Red and Near Infrared Light Transmission in a Cadaveric Model

Jared R. Jagdeo et al.

PLOS ONE (2012)

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Editorial Material Surgery

Potential for Transcranial Laser or LED Therapy to Treat Stroke, Traumatic Brain Injury, and Neurodegenerative Disease

Margaret A. Naeser et al.

PHOTOMEDICINE AND LASER SURGERY (2011)

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Article Multidisciplinary Sciences

Simulation of Near-Infrared Light Absorption Considering Individual Head and Prefrontal Cortex Anatomy: Implications for Optical Neuroimaging

Florian B. Haeussinger et al.

PLOS ONE (2011)

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Article Neurosciences

Neuroprotection of Midbrain Dopaminergic Cells in MPTP-Treated Mice after Near-infrared Light Treatment

Victoria E. Shaw et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2010)

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Article Clinical Neurology

A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson's Disease

Kelvin L. Chou et al.

MOVEMENT DISORDERS (2010)

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Article Clinical Neurology

The 39 item Parkinson's disease questionnaire (PDQ-39) revisited: implications for evidence based medicine

Peter Hagell et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2007)

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Article Pharmacology & Pharmacy

Sample size of 12 per group rule of thumb for a pilot study

SA Julious

PHARMACEUTICAL STATISTICS (2005)

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Article Clinical Neurology

Systematic evaluation of rating scales for impairment and disability in Parkinson's disease

C Ramaker et al.

MOVEMENT DISORDERS (2002)

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Protocol for randomized controlled trial to evaluate the safety and feasibility of a novel helmet to deliver transcranial light emitting diodes photobiomodulation therapy to patients with Parkinson's disease

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