Recent Advances of Green Catalytic System I2/DMSO in C-C and C-Heteroatom Bonds Formation

Developing a green, practical and efficient method for the formation of C-C and C-Heteroatom bonds is an important topic in modern organic synthetic chemistry. In recent years, the I-2/DMSO catalytic system has attracted wide attention because of its green, high efficiency, atomic economy, low cost, mild reaction conditions and it is environment-friendly, which is more in line with the requirements of sustainable chemistry. Heteroatom-containing compounds have shown lots of important applications in pharmaceutical synthesis, agrochemicals, material chemistry and organic dyes. At present, the I-2/DMSO catalytic system has been successfully applied to the synthesis of various heteroatom-containing compounds. The C-C and C-Heteroatom bonds have been formed efficiently, which has been proved to be a green and mild catalytic system. In this review, the research achievements of the I-2/DMSO catalytic system in the formation of C-C and C-Heteroatom bonds from 2015 to date are described, and the research area is prospected. This review attempts to reveal the general law of iodine catalysis and lay a foundation for the design of new reactions.

Automated summary

Developing a green, practical, and efficient method for the formation of C-C and C-Heteroatom bonds is crucial in modern organic synthetic chemistry. The I-2/DMSO catalytic system has attracted wide attention due to its green, high efficiency, low cost, and environmentally friendly properties. It has been successfully applied to the synthesis of various heteroatom-containing compounds, forming C-C and C-Heteroatom bonds efficiently.