期刊
BRAIN AND BEHAVIOR
卷 12, 期 9, 页码 -出版社
WILEY
DOI: 10.1002/brb3.2740
关键词
Alzheimer's disease; dementia; Lewy body dementia; Parkinson's disease; stem cells
Stem cell therapy has the potential to positively modify degenerative changes in dementia, but ethical concerns and the risk of uncontrolled cell differentiation leading to cancer development must be addressed. However, if appropriately developed, stem cell therapy could offer a viable treatment option for patients with dementia. Further research and clinical trials are needed to establish its efficacy in this context.
Aim This article aims to study the benefits and disadvantages of stem cell therapy, especially for patients who have dementia. Methods The databases PubMed, Google Scholar, and the National Library of Medicine were searched for literature. All papers on Alzheimer's disease, Lewy body dementia, Parkinson's disease, stem cell therapy, and its effect on dementia treatment were considered. Results Stem cell treatment has demonstrated promising outcomes in animal studies by positively modifying the degenerative alterations in dementia. However, it is not without drawbacks, such as ethical concerns while using embryonic stem cells and the danger of developing cancer if the cells undergo uncontrolled differentiation. Conclusion Although stem cell therapy has its risks, it has the potential to be a viable therapeutic option for patients with dementia if developed appropriately. Hence, more research and clinical trials are needed to establish its efficacy in this context.
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