期刊
JOURNAL OF ENDODONTICS
卷 42, 期 3, 页码 474-479出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.joen.2015.10.014
关键词
Biocompatibility; mineral trioxide aggregate; physical properties; propylene glycol
资金
- State of Sao Paulo Research Foundation (FAPESP) [2013/04054-8, 2014/01003-6]
- CNPq [310915/2012-0]
- University of Malta Research Grant committee and the Faculty of Dental Surgery
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [13/04054-8] Funding Source: FAPESP
Introduction: The aim of this study was to evaluate the physical, chemical, and biological properties of mineral trioxide aggregate (MTA) mixed with 80% distilled water and 20% propylene glycol (PG) compared with MTA mixed with distilled water only. Methods: Flowability, film thickness, and solubility were analyzed according to American National Standards Institute/American Dental Association specification 57/2000. Initial and final setting times were assessed according to American Society for Testing and Materials specification C266/08. Porosity was assessed by using mercury intrusion porosimetry after 1 and 28 days of hydration, and the pH and calcium ion release were assessed after 3, 24, 72, and 168 hours. For the tissue reaction, the cements were implanted in 24 albino rats (2 groups, n = 12). An analysis of the inflammatory infiltrate was performed after 15, 30, and 60 days. Results: MTA + PG exhibited lower film thickness and higher final setting time. No differences were verified for flowability (P > .05). MTA PG showed high porosity at 1 day of hydration (P < .05). All the test cements demonstrated an alkaline pH. Microscopic analysis of the specimens revealed neoformation of connective tissue in contact with the cements. Conclusions: The introduction of PG as a mixing vehicle alters the physical and chemical properties of MTA and is biologically acceptable.
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