Recent Advances of Optical Sensors for Copper Ion Detection

A trace element copper (Cu2+) ion is the third most plentiful metal ion that necessary for all living organisms and playing a critical role in several processes. Nonetheless, according to cellular needs, deficient or excess Cu2+ ion cause various diseases. For all these reasons, optical sensors have been focused rapid Cu2+ ion detection in real-time with high selectivity and sensitivity. Optical sensors can measure fluorescence in the refractive index-adsorption from the relationships between light and matter. They have gained great attention in recent years due to the excellent advantages of simple and naked eye recognition, real-time detection, low cost, high specificity against analytes, a quick response, and the need for less complex equipment in analysis. This review aims to show the significance of Cu2+ ion detection and electively current trends in optical sensors. The integration of optical sensors with different systems, such as microfluidic systems, is mentioned, and their latest studies in medical and environmental applications also are depicted. Conclusions and future perspectives on these advances is added at the end of the review.

Automated summary

Copper ions play a crucial role in living organisms, but deficiency or excess can lead to diseases. Optical sensors, with their advantages of simplicity, real-time detection, low cost, high specificity, and quick response, have gained attention for rapid and selective detection of copper ions. This review highlights the importance of copper ion detection and current trends in optical sensors, including their integration with different systems and applications in medicine and environment.