☆ 4.7 Article

Traditional Chinese medicine active ingredients-based selenium nanoparticles regulate antioxidant selenoproteins for spinal cord injury treatment

JOURNAL OF NANOBIOTECHNOLOGY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Neurosciences

A mechanistic overview of spinal cord injury, oxidative DNA damage repair and neuroprotective therapies

Jaspreet Kaur et al.

Summary: Despite significant advancements in medical treatment strategies, finding a cure for spinal cord injury (SCI) remains challenging. Oxidative DNA damage is a severe consequence of secondary injury, and understanding the impact of cellular and molecular biology on the pathophysiology of SCI is crucial. Thus, the aim of this review is to bridge the gaps and shed light on the functional repair mechanisms in neurons following injury, as well as investigate the significance of neuroprotective strategies in the current scenario.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bioactive Nanoenzyme Reverses Oxidative Damage and Endoplasmic Reticulum Stress in Neurons under Ischemic Stroke

Guanning Huang et al.

Summary: This study designed a translational antioxidative agent, HSA-Mn3O4, which effectively inhibits nervous system damage caused by ischemic stroke reperfusion, demonstrating neuroprotective capacity mainly by inhibiting apoptosis and endoplasmic reticulum stress to prevent brain tissue damage.

ACS NANO (2022)

添加到收藏夹

Article Engineering, Environmental

Mannose-rich Oligosaccharides-functionalized selenium nanoparticles mediates Macrophage reprogramming and inflammation resolution in ulcerative colitis

Hui Yang et al.

Summary: In this study, a bioactive component of mannose-rich oligosaccharides (MRO) was produced and used to functionalize selenium nanoparticles (SeNPs) in order to reprogram macrophages and mitigate inflammation in inflammatory bowel disease (IBD). The MRO-functionalized SeNPs showed improved stability and biocompatibility, and effectively suppressed pro-inflammatory cytokines in a mouse colitis model. This study not only provides a strategy for functionalizing nanomedicines, but also reveals the mechanism of successful treatment of IBD and other intestinal diseases.

CHEMICAL ENGINEERING JOURNAL (2022)

添加到收藏夹

Review Medicine, Research & Experimental

A critical review of Astragalus polysaccharides: From therapeutic mechanisms to pharmaceutics

Yu Du et al.

Summary: Astragalus polysaccharides (APs), as important active ingredients of Astragali Radix, have therapeutic potential for multiple diseases. However, their low bioavailability limits their clinical application. Nanocrystals and structural modification of APs have been shown to improve bioavailability, potentially expanding their application.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Current Policies and Measures on the Development of Traditional Chinese Medicine in China

Wan-Ying Wang et al.

Summary: Traditional Chinese Medicine (TCM) is a medical science and cultural heritage that has been empirically applied and preserved by the Chinese people for thousands of years. With the comprehensive prosperity of China and rapid advancement in technology, the healthcare status of the Chinese people has become one of the country's most crucial concerns. Since the 18th National Congress of the Communist Party of People's Republic of China in 2012, nearly 30 policies and measures regarding TCM development have been issued.

PHARMACOLOGICAL RESEARCH (2021)

添加到收藏夹

Article Engineering, Biomedical

Rapid visualizing and pathological grading of bladder tumor tissues by simple nanodiagnostics

Hongxing Liu et al.

Summary: The study developed a stable cancer-targeted selenium nanosystem for specifically recognizing and staining tumor cells without the need for antibodies, enabling differentiation of different pathological grades.

BIOMATERIALS (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Edible CaCO3 nanoparticles stabilized Pickering emulsion as calcium-fortified formulation

Xiaoming Guo et al.

Summary: Edible oil-in-water Pickering emulsion structured by calcium carbonate nanoparticles showed potential for delivering lipophilic drugs and oral calcium supplementation. The microstructure of the emulsion could be controlled by adjusting particle concentration and oil volume fraction. The emulsion displayed acid-triggered demulsification in simulated gastric environment, enhancing the bioavailability of encapsulated vitamin D3.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Macrophage-biomimetic porous Se@SiO2 nanocomposites for dual modal immunotherapy against inflammatory osteolysis

Cheng Ding et al.

Summary: The research found that macrophage membrane-coated porous Se@SiO2 nanospheres alleviated LPS-induced inflammatory osteolysis through dual immunomodulatory effect, promoting polarization of macrophages towards the anti-inflammatory M2 phenotype. These nanoparticles reduced endotoxin levels, neutralized proinflammatory cytokines, and inhibited p65, p38, and ERK signaling pathways, leading to alleviation of the inhibition of osteogenic differentiation caused by proinflammatory cytokines.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Application of nanotechnology in the diagnosis and treatment of bladder cancer

Yadong Xu et al.

Summary: Bladder cancer remains a common malignancy with unsatisfactory theranostic approaches. Nanotechnology has shown promising potential in improving efficiency of diagnosis and treatment through targeted delivery of agents and distinguishing normal and abnormal bladder tissues. Future research on novel nanoparticles for bladder cancer management is encouraged.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Article Integrative & Complementary Medicine

Efficacy of Yangyin Yiqi Huoxue Granule in Treatment of Ischemic Stroke Patients with Qi-Yin Deficiency and Blood Stasis Syndrome: A Randomized, Double-Blind, Multicenter, Phase-2 Clinical Trial

Wang Yu et al.

Summary: The study confirmed that high-dose Yangyin Yiqi Huoxue Granule is more effective in the treatment of ischemic stroke patients with qi-yin deficiency and blood stasis syndrome, and also demonstrated a certain level of safety. The efficacy was mainly reflected in the comprehensive cure rate and improvements in related scores.

CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

BuqiTongluo Granule for Ischemic Stroke, Stable Angina Pectoris, Diabetic Peripheral Neuropathy with Qi Deficiency and Blood Stasis Syndrome: Rationale and Novel Basket Design

Weidi Liu et al.

Summary: This study aims to compare the efficacy of BQTL granules with placebo in multiple diseases with QDBS syndrome through a basket trial. By utilizing observable phenotypic changes, the study seeks to discover novel treatments for these diseases.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Pharmacological management of secondary spinal cord injury

Alice Baroncini et al.

Summary: Secondary spinal cord injury (SCI) occurs immediately after trauma and may become chronic despite prompt treatment. This review discusses the pathophysiological mechanisms leading to secondary SCI and the outlook for pharmacological management through clinical trials. Pharmacological therapy aims to improve motor and sensory function in patients, but as of now, no drug has completed a stage III trial for SCI management.

EXPERT OPINION ON PHARMACOTHERAPY (2021)

添加到收藏夹

Article Engineering, Biomedical

Translational Nanotherapeutics Reprograms Immune Microenvironment in Malignant Pleural Effusion of Lung Adenocarcinoma

Zhenhuan Song et al.

Summary: A translational selenium nanoparticles coated with immune-modulating macromolecule lentinan are designed to restore dysfunctional immune cells in patient-derived malignant pleural effusion microenvironment, enhancing immune responses and inhibiting tumor growth, thereby providing a potential therapeutic strategy for advanced lung cancer patients with MPE.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Biochemical Research Methods

Urinary metabolomic profiling reveals difference between two traditional Chinese medicine subtypes of coronary heart disease

Na Guo et al.

Summary: This study used untargeted and targeted metabolomics approaches to explore the significantly different metabolites related to the Qi stagnation with blood stasis or Qi deficiency with blood stasis subtypes of coronary heart disease (CHD) with angina pectoris. The results showed distinct metabolic profiles not only between CHD patients and healthy controls, but also between the two subtypes of CHD. Pathway analysis revealed subtype-related differences in the activity of pathways, demonstrating the potential of urinary metabolomics in providing evidence for personalized treatment of CHD.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Tanshinone IIA: A phytochemical as a promising drug candidate for neurodegenerative diseases

Lalita Subedi et al.

Summary: Tanshinones, specifically tanshinone IIA, isolated from the rhizome of Salvia miltiorrhiza, have shown diverse pharmacological activities and neuroprotective effects against neurological diseases. Experimental studies have suggested that tanshinone IIA can attenuate blood-brain barrier permeability among stroke patients, making it an appealing therapeutic candidate for neurological diseases. Additionally, tanshinones have demonstrated effectiveness in experimental models of Parkinson's disease, Multiple sclerosis, and other neuroinflammatory diseases.

PHARMACOLOGICAL RESEARCH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Designing highly stable ferrous selenide-black phosphorus nanosheets heteronanostructure via P-Se bond for MRI-guided photothermal therapy

Xuanru Deng et al.

Summary: This study successfully designed a black phosphorus-based theranostic agent that can achieve MRI-guided precision photothermal therapy with good water solubility. By effectively separating photoinduced carriers and weakening the oxidation degree of ferrous selenide, the theranostic agent exhibits high photothermal conversion efficiency and excellent stability.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

添加到收藏夹

Article Materials Science, Biomaterials

Selenium-driven enhancement of synergistic cancer chemo-/radiotherapy by targeting nanotherapeutics

Xinxin Liu et al.

Summary: The development of a nano-radiosensitizer can enhance the efficacy of cervical cancer radiotherapy by inducing apoptosis and increasing the sensitivity of cancer cells to X-ray radiation. The nanosystem can inhibit tumor growth effectively and shows minimal toxicity in vivo in mice.

BIOMATERIALS SCIENCE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Chirality-Driven Transportation and Oxidation Prevention by Chiral Selenium Nanoparticles

Yanyu Huang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Article Cell Biology

Polydatin promotes the neuronal differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: Involvement of Nrf2 signalling pathway

Jiheng Zhan et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

添加到收藏夹

Review Plant Sciences

Compound-based Chinese medicine formula: From discovery to compatibility mechanism

Xin Luan et al.

JOURNAL OF ETHNOPHARMACOLOGY (2020)

添加到收藏夹

Article Plant Sciences

Mechanisms exploration of herbal pair of HuangQi-DanShen on cerebral ischemia based on metabonomics and network pharmacology

YueTao Liu et al.

JOURNAL OF ETHNOPHARMACOLOGY (2020)

添加到收藏夹

Article Cell Biology

PC12 Cell Line: Cell Types, Coating of Culture Vessels, Differentiation and Other Culture Conditions

Benita Wiatrak et al.

CELLS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Microenvironment-responsive immunoregulatory electrospun fibers for promoting nerve function recovery

Kun Xi et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Selenium nanoparticles regulates selenoprotein to boost cytokine-induced killer cells-based cancer immunotherapy

Ting Liu et al.

NANO TODAY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Lentinan-functionalized selenium nanosystems with high permeability infiltrate solid tumors by enhancing transcellular transport

Fan Yang et al.

NANOSCALE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Preparation and drug release property of tanshinone IIA loaded chitosan-montmorillonite microspheres

Chao Luo et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

添加到收藏夹

Review Cell Biology

The Importance of Natural Antioxidants in the Treatment of Spinal Cord Injury in Animal Models: An Overview

Angelica Coyoy-Salgado et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Highly Uniform Synthesis of Selenium Nanoparticles with EGFR Targeting and Tumor Microenvironment-Responsive Ability for Simultaneous Diagnosis and Therapy of Nasopharyngeal Carcinoma

Jing Huang et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Materials Science, Biomaterials

Designing multifunctionalized selenium nanoparticles to reverse oxidative stress-induced spinal cord injury by attenuating ROS overproduction and mitochondria dysfunction

Siyuan Rao et al.

JOURNAL OF MATERIALS CHEMISTRY B (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Extraction of a Novel Cold-Water-Soluble Polysaccharide from Astragalus membranaceus and Its Antitumor and Immunological Activities

An-jun Liu et al.

MOLECULES (2018)

添加到收藏夹

Article Materials Science, Biomaterials

Polysaccharide-protein complex-decorated selenium nanosystem as an efficient bone-formation therapeutic

Siming Yu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2018)

添加到收藏夹

Review Nutrition & Dietetics

Selenium, Selenoproteins, and Immunity

Joseph C. Avery et al.

NUTRIENTS (2018)

添加到收藏夹

Article Materials Science, Biomaterials

Autophagy is an important action mode for functionalized selenium nanoparticles to exhibit anti-colorectal cancer activity

Guanning Huang et al.

BIOMATERIALS SCIENCE (2018)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Nano based drug delivery systems: recent developments and future prospects

Jayanta Kumar Patra et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

Selenium-Dependent Antioxidant Enzymes: Actions and Properties of Selenoproteins

Evangelos Zoidis et al.

ANTIOXIDANTS (2018)

添加到收藏夹

Article Agriculture, Multidisciplinary

Phycocyanin-Functionalized Selenium Nanoparticles Reverse Palmitic Acid-Induced Pancreatic β Cell Apoptosis by Enhancing Cellular Uptake and Blocking Reactive Oxygen Species (ROS)-Mediated Mitochondria Dysfunction

Chang Liu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Antioxidant capacities of the selenium nanoparticles stabilized by chitosan

Xiaona Zhai et al.

JOURNAL OF NANOBIOTECHNOLOGY (2017)

添加到收藏夹

Article Biology

Detection of Reactive Oxygen Species (ROS) in Cyanobacteria Using the Oxidant-sensing Probe 2′,7′-Dichlorodihydrofluorescein Diacetate (DCFH-DA)

Rajneesh et al.

BIO-PROTOCOL (2017)

添加到收藏夹

Article Biochemical Research Methods

Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges

Dimitrios Tsikas

ANALYTICAL BIOCHEMISTRY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Selenium Nanoparticles Attenuate Oxidative Stress and Testicular Damage in Streptozotocin-Induced Diabetic Rats

Mohamed A. Dkhil et al.

MOLECULES (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Efficacy-oriented compatibility for component-based Chinese medicine

Jun-hua Zhang et al.

ACTA PHARMACOLOGICA SINICA (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Effects and Perspectives of Chinese Patent Medicines for Tonifying Qi and Promoting Blood Circulation on Patients with Cerebral Infarction

Li Zhou et al.

CURRENT VASCULAR PHARMACOLOGY (2015)

添加到收藏夹

Review Biochemistry & Molecular Biology

Structural features and biological activities of the polysaccharides from Astragalus membranaceus

Mingliang Jin et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

Selenium and Selenoprotein Function in Brain Disorders

Roshan Pillai et al.

IUBMB LIFE (2014)

添加到收藏夹

Review Cell Biology

Mitochondria-mediated apoptosis in mammals

Shunbin Xiong et al.

PROTEIN & CELL (2014)

添加到收藏夹

Article Engineering, Biomedical

Selective cellular uptake and induction of apoptosis of cancer-targeted selenium nanoparticles

Yanyu Huang et al.

BIOMATERIALS (2013)

添加到收藏夹

Article Plant Sciences

Myelophil attenuates brain oxidative damage by modulating the hypothalamus-pituitary-adrenal (HPA) axis in a chronic cold-stress mouse model

Hyeong-Geug Kim et al.

JOURNAL OF ETHNOPHARMACOLOGY (2013)

添加到收藏夹

Article Plant Sciences

Pharmacokinetics, absorption and tissue distribution of tanshinone IIA solid dispersion

Haiping Hao et al.

PLANTA MEDICA (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.