Novel Glucosylimidazolium Ionic-Liquid-Supported Novozym 435 Catalysts - A Proof of Concept for an Acrylation Reaction

A series of novel ionic liquids based on glucose was synthesized in high yields in simple two or three-step reaction procedures. These carbohydrate-based ionic liquids were studied and compared to commercially available imidazolium-based ionic liquids as supports for Novozym 435 in the acrylation of n-butanol. A direct correlation between the availability of hydroxy groups and the overall activity as well as an enhanced recyclability of the biocatalyst has been found for the glucose-based ionic liquids.

Automated summary

A series of novel glucose-based ionic liquids were synthesized in high yields using simple reaction procedures. These ionic liquids were compared to commercially available imidazolium-based ionic liquids as supports for Novozym 435 in the acrylation of n-butanol. It was found that the availability of hydroxy groups in the glucose-based ionic liquids correlated directly with the overall activity and enhanced recyclability of the biocatalyst.