4.6 Article

Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by integrated stress response regulators Gcn1 and Gcn20

Lisa Houston et al.

Summary: This study reveals the factors involved in frameshifting during ribosome collisions and finds that eEF3, Gcn1, and Gcn20 have opposing roles in modulating frameshifting. The results show that eEF3 facilitates tRNA-mRNA translocation and E-site tRNA release, thereby suppressing frameshifting; while Gcn1 and Gcn20 bind to collided ribosomes and increase frameshifting. Additionally, Mbf1 requires He12 or Gcn1 to suppress frameshifting.
Article Biochemistry & Molecular Biology

Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by integrated stress response regulators Gcn1 and Gcn20

Lisa Houston et al.

Summary: Research has shown that in Saccharomyces cerevisiae, the translation elongation factor eEF3 and the integrated stress response (ISR) pathway components Gcn1 and Gcn20 modulate frameshifting in opposing manners. eEF3 facilitates tRNA-mRNA translocation and E-site tRNA release, suppressing frameshifting, while removal of Gcn1 and Gcn20 increases frameshifting.
Review Cell Biology

The expanding world of tRNA modifications and their disease relevance

Tsutomu Suzuki

Summary: tRNAs undergo heavy post-transcriptional modifications, which play crucial roles in accurate codon recognition and reading frame maintenance during protein synthesis. Recent studies have shown that tRNA modifications can be dynamically altered in response to cellular and environmental stresses, and deficiencies in tRNA modification can lead to mitochondrial diseases, neurological disorders, and cancer.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation

Esteban A. Orellana et al.

Summary: The study revealed that METTL1 is frequently overexpressed in cancer, affecting tRNA modification and the cell cycle, promoting oncogenesis. Additionally, it was found that overexpression of a specific tRNA can induce oncogenic transformation.

MOLECULAR CELL (2021)

Article Plant Sciences

The Arabidopsis TRM61/TRM6 complex is a bona fide tRNA N1-methyladenosine methyltransferase

Jun Tang et al.

JOURNAL OF EXPERIMENTAL BOTANY (2020)

Review Biochemistry & Molecular Biology

The emerging impact of tRNA modifications in the brain and nervous system

Jillian Ramos et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2019)

Article Biochemistry & Molecular Biology

MODOMICS: a database of RNA modification pathways. 2017 update

Pietro Boccaletto et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

Molecular mechanism for the inhibition of DXO by bisphosphate

Ji-Sook Yun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

ALKBH1-Mediated tRNA Demethylation Regulates Translation

Fange Liu et al.

Article Genetics & Heredity

Genetic evidence for involvement of membrane trafficking in the action of 5-fluorouracil

Lingling Hu et al.

FUNGAL GENETICS AND BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

Danny D. Nedialkova et al.

Review Biochemistry & Molecular Biology

XRN 5′ → 3′ exoribonucleases: Structure, mechanisms and functions

Vinay K. Nagarajan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2013)

Article Biochemistry & Molecular Biology

Degradation of initiator tRNAMet by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells

Kazunori Watanabe et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

Retrograde transfer RNA nuclear import provides a new level of tRNA quality control in Saccharomyces cerevisiae

Emily B. Kramer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Extensive Degradation of RNA Precursors by the Exosome in Wild-Type Cells

Rajani Kanth Gudipati et al.

MOLECULAR CELL (2012)

Review Biochemistry & Molecular Biology

A mechanistic overview of translation initiation in eukaryotes

Colin Echeverria Aitken et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Biochemistry & Molecular Biology

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

Francesca Tuorto et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Review Cell Biology

The many roles of the eukaryotic elongation factor 1 complex

Arjun N. Sasikumar et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)

Article Biochemistry & Molecular Biology

A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification

Basma El Yacoubi et al.

EMBO JOURNAL (2011)

Article Multidisciplinary Sciences

Estimating the timing of early eukaryotic diversification with multigene molecular clocks

Laura Wegener Parfrey et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biochemistry & Molecular Biology

Eukaryotic initiator tRNA: Finely tuned and ready for action

Sarah E. Kolitz et al.

FEBS LETTERS (2010)

Review Cell Biology

tRNA biology charges to the front

Eric M. Phizicky et al.

GENES & DEVELOPMENT (2010)

Article Biotechnology & Applied Microbiology

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

Dong-Uk Kim et al.

NATURE BIOTECHNOLOGY (2010)

Article Biochemistry & Molecular Biology

Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14

Claudia Keller et al.

Review Biochemistry & Molecular Biology

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

Nahum Sonenberg et al.

Article Biochemical Research Methods

Enzymatic assembly of DNA molecules up to several hundred kilobases

Daniel G. Gibson et al.

NATURE METHODS (2009)

Review Biochemistry & Molecular Biology

The nuclear RNA surveillance machinery: The ncRNAs and genome structure in budding link between yeast?

Jonathan Houseley et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2008)

Article Biochemistry & Molecular Biology

Eukaryotic wobble uridine modifications promote a functionally redundant decoding system

Marcus J. O. Johansson et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Transcription and RNAi in heterochromatic gene silencing

Marc Buehler et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

The exosome subunit Rrp44 plays a direct role in RNA substrate recognition

Claudia Schneider et al.

MOLECULAR CELL (2007)

Article Biochemistry & Molecular Biology

Separate RNA-binding surfaces on the multifunctional La protein mediate distinguishable activities in tRNA maturation

Ying Huang et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Requirement of fission yeast Cid14 in polyadenylation of rRNAs

TZ Win et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Rapid tRNA decay can result from lack of nonessential modifications

A Alexandrov et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

RNA degradation by the exosome is promoted by a nuclear polyade nylation complex

J LaCava et al.

Review Microbiology

Translational regulation of GCN4 and the general amino acid control of yeast

AG Hinnebusch

ANNUAL REVIEW OF MICROBIOLOGY (2005)

Article Biochemistry & Molecular Biology

Improvement of reading frame maintenance is a common function for several tRNA modifications

J Urbonavicius et al.

EMBO JOURNAL (2001)

Article Multidisciplinary Sciences

The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae

J Anderson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)