4.6 Review

Efficacy of Traditional Chinese Exercise in Improving Gait and Balance in Cases of Parkinson's Disease: A Systematic Review and Meta-analysis

期刊

FRONTIERS IN AGING NEUROSCIENCE
卷 14, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fnagi.2022.927315

关键词

traditional Chinese exercise; gait; balance; Parkinson's disease; meta-analysis

资金

  1. Natural Science Foundation of Heilongjiang Province [JJ2020LH1369]
  2. Applied Technology Research and Development Program of Heilongjiang Province [GA19C110]
  3. National Key Research and Development Program [2019YFC1710304]

向作者/读者索取更多资源

This study aimed to assess the effects of traditional Chinese exercise (TCE) on balance, gait, and motor symptoms in patients with Parkinson's disease (PD). The results showed that TCE significantly improved balance, gait, and motor symptoms in PD patients. Furthermore, the dosage and related variables of TCE may moderate its effects.
Background: The efficacy of traditional Chinese exercise (TCE)-based intervention in the improvement of motor function in patients with Parkinson's disease (PD) is controversial. The present study aimed to assess the effects of TCE on balance and gait outcomes, as well as motor symptoms in individuals with PD, and evaluate potential discrete moderators such as TCE dosage-related variables. Method: PubMed, Embase, Cochrane's Library, Web of Science, Medline, and Scopus were systematically searched from their dates of inception to February 2022. All studies were randomized controlled trials (RCTs) of TCE-based interventions for PD. The treatment effects were estimated using a random-effect meta-analysis model with standardized mean differences (Hedges' g). The Physiotherapy Evidence Database was used to evaluate the methodological quality of the study. Result: Fifteen studies involving a total of 873 participants were included in the final analysis. The meta-analytic findings revealed significant improvements in balance outcomes [Berg Balance Scales (BBS) (g = 0.83, 95% CI = 0.37-1.29, p = 0.000, I-2 = 84%), time up and go (TUG) (g = -0.80, 95% CI = -1.13- -0.47, p = 0.000, I-2 = 81%), and the one legged blind balance test (g = 0.49, 95% CI = 0.13-0.86, p = 0.01, I-2 = 10%)], as well as gait outcomes [gait velocity (g = 0.28, 95% CI = 0.02-0.54, p = 0.04, I-2 = 64%), 6-min walking test (6MWT) (g = 0.32, 95% CI 0.01-0.62, p = 0.04, I-2= 15%), stride length (g = 0.25, 95% CI = 0.08-0.41, p = 0.003, I-2 = 42%)], and motor symptoms [Unified Parkinson's Disease Rating Scale part III (UPDRS-III) (g = -0.77, 95% CI = -1.06- -0.48, p = 0.000, I-2 = 76%)]. However, cadence (g = -0.03) and step length (g = 0.02) did not differ significantly. The moderator shows that the effects of TCE on BBS and gait velocity were moderated by Pedro score, exercise type, control group type, and number of sessions. Meta-regression found that TCE (exercise duration, number of sessions, and session duration) was significantly associated with improved UPDRS-III and BBS scores. Conclusion: These findings provide evidence for the therapeutic benefits of TCE as an adjunct therapy for patients with PD. TEC dosage (high-intensity long sessions) may moderate some favorable effects.Systematic Review RegistrationPROSPERO, identifier CRD42022314686.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据