相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Spinster homolog 2 in cancers, its functions and mechanisms
Lian Fang et al.
CELLULAR SIGNALLING (2021)
Endothelial S1P1 Signaling Counteracts Infarct Expansion in Ischemic Stroke
Anja Nitzsche et al.
CIRCULATION RESEARCH (2021)
Loss of sphingosine 1-phosphate receptor 3 gene function impairs injury-induced stromal angiogenesis in mouse cornea
Shingo Yasuda et al.
LABORATORY INVESTIGATION (2021)
The S1P2 receptor regulates blood-brain barrier integrity and leukocyte extravasation with implications for neurodegenerative disease
Ping Xiang et al.
NEUROCHEMISTRY INTERNATIONAL (2021)
Vascular endothelial cell specification in health and disease
Corina Marziano et al.
ANGIOGENESIS (2021)
Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis
Yu-Chi Chen et al.
CANCER LETTERS (2021)
Sphingosine 1-Phosphate Receptor Modulators for Multiple Sclerosis
Reshmi Roy et al.
CNS DRUGS (2021)
Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis
Tamara Perez-Jeldres et al.
DRUGS (2021)
Deletion of Mfsd2b impairs thrombotic functions of platelets
Madhuvanthi Chandrakanthan et al.
NATURE COMMUNICATIONS (2021)
Subtype-dependent regulation of Gβγ signalling
Mithila Tennakoon et al.
CELLULAR SIGNALLING (2021)
Inhibition of S1P Receptor 2 Attenuates Endothelial Dysfunction and Inhibits Atherogenesis in Apolipoprotein E-Deficient Mice
Byambasuren Ganbaatar et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2021)
Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage
Lifang Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2021)
Endothelial Dysfunction in Atherosclerotic Cardiovascular Diseases and Beyond: From Mechanism to Pharmacotherapies
Suowen Xu et al.
PHARMACOLOGICAL REVIEWS (2021)
Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
Sakiko Honda et al.
SCIENTIFIC REPORTS (2021)
S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation
Jian Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
S1PR1-Associated Molecular Signature Predicts Survival in Patients with Sepsis
Anlin Feng et al.
SHOCK (2020)
Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung
Lisandra Vila Ellis et al.
DEVELOPMENTAL CELL (2020)
Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization
Keisuke Yanagida et al.
DEVELOPMENTAL CELL (2020)
Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis
Ilaria Del Gaudio et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy
Andreane Cartier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Overexpression of Sphingosine Kinase-1 and Sphingosine-1-Phosphate Receptor-3 in Severe Plasmodium falciparum Malaria with Pulmonary Edema
Parnpen Viriyavejakul et al.
BIOMED RESEARCH INTERNATIONAL (2020)
Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
Eric Engelbrecht et al.
ELIFE (2020)
A cellular perspective of bias at G protein-coupled receptors
Thomas J. Fernandez et al.
PROTEIN SCIENCE (2020)
Vascular Signaling in Allogenic Solid Organ Transplantation - The Role of Endothelial Cells
Laura Kummer et al.
FRONTIERS IN PHYSIOLOGY (2020)
Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics
Eelke P. Beguin et al.
MOLECULAR & CELLULAR PROTEOMICS (2020)
Exogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1
Ruth R. Magaye et al.
CELLULAR SIGNALLING (2020)
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
Taylor S. Adams et al.
SCIENCE ADVANCES (2020)
S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling
Xin Geng et al.
JCI INSIGHT (2020)
Single-Nucleus RNA-Sequencing Profiling of Mouse Lung Reduced Dissociation Bias and Improved Rare Cell-Type Detection Compared with Single-Cell RNA Sequencing
Jeffrey R. Koenitzer et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)
Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology
E. Jozefczuk et al.
PHARMACOLOGICAL RESEARCH (2020)
Conformational Basis of G Protein-Coupled Receptor Signaling Versatility
Laura M. Wingler et al.
TRENDS IN CELL BIOLOGY (2020)
HDL-S1P protects endothelial function and reduces lung injury during sepsis in vivo and in vitro
YiWen Fan et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2020)
Targeted role for sphingosine-1-phosphate receptor 1 in cerebrovascular integrity and inflammation during acute ischemic stroke
Yu-Jing Li et al.
NEUROSCIENCE LETTERS (2020)
The role of extracellular vesicles in neointima formation post vascular injury
A. Pashova et al.
CELLULAR SIGNALLING (2020)
Complex roles of cAMP-PKA-CREB signaling in cancer
Hongying Zhang et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2020)
Single Cell Analysis in Vascular Biology
Nicholas W. Chavkin et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)
Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers
Manal H. Saad et al.
SCIENTIFIC REPORTS (2019)
Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells
Samuel W. Lukowski et al.
CELL REPORTS (2019)
Myeloid sphingosine-1-phosphate receptor 1 is important for CNS autoimmunity and neuroinflammation
Hsing-Chuan Tsai et al.
JOURNAL OF AUTOIMMUNITY (2019)
Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes
Yu Hisano et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation
Timothy A. Norman et al.
PLOS ONE (2019)
Sphingosine 1-Phosphate Receptors and Metabolic Enzymes as Druggable Targets for Brain Diseases
Sara Grassi et al.
FRONTIERS IN PHARMACOLOGY (2019)
Identification of ApoA4 as a sphingosine 1-phosphate chaperone in ApoM- and albumin-deficient mice[S]
Hideru Obinata et al.
JOURNAL OF LIPID RESEARCH (2019)
Expression of sphingosine kinase 1 and sphingosine 1-phosphate receptor 3 in malaria-associated acute lung injury/acute respiratory distress syndrome in a mouse model
Chuchard Punsawad et al.
PLOS ONE (2019)
High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node
Szandor Simmons et al.
ELIFE (2019)
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation
Changchun Cao et al.
CELLULAR SIGNALLING (2019)
Combination of sphingosine-1-phosphate receptor 1 (S1PR1) agonist and antiviral drug: a potential therapy against pathogenic influenza virus
Jiangnan Zhao et al.
SCIENTIFIC REPORTS (2019)
Sphingosine-1-phosphate (S1P) enhances glomerular endothelial cells activation mediated by anti-myeloperoxidase antibody-positive IgG
Xiao-Jing Sun et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells
K. Vrzalikova et al.
LEUKEMIA (2018)
Upregulated Sphingosine 1-Phosphate Receptor 1 Expression in Human and Murine Atherosclerotic Plaques
Hui Liu et al.
MOLECULAR IMAGING AND BIOLOGY (2018)
Identification of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) as a Pathogenic Factor in Transient Focal Cerebral Ischemia
Bhakta Prasad Gaire et al.
MOLECULAR NEUROBIOLOGY (2018)
Sphingolipids and their metabolism in physiology and disease
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
High-density lipoprotein (HDL) promotes angiogenesis via S1P3-dependent VEGFR2 activation
Fengyan Jin et al.
ANGIOGENESIS (2018)
Sphingosine-1-phosphate promotes the proliferation and attenuates apoptosis of Endothelial progenitor cells via S1PR1/S1PR3/PI3K/Akt pathway
Hang Wang et al.
CELL BIOLOGY INTERNATIONAL (2018)
Sphingosine-1-phosphate receptor 1 mediates elevated IL-6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease
Shushan Zhao et al.
FASEB JOURNAL (2018)
Stimulation of S1PR(5) with A-971432, a selective agonist, preserves blood-brain barrier integrity and exerts therapeutic effect in an animal model of Huntington's disease
Alba Di Pardo et al.
HUMAN MOLECULAR GENETICS (2018)
Rho GTPases are involved in S1P-enhanced glomerular endothelial cells activation with anti-myeloperoxidase antibody positive IgG
Xiao-Jing Sun et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Sphingosine-1-Phosphate Receptor 1 Activation Enhances Leptomeningeal Collateral Development and Improves Outcome after Stroke in Mice
Eri Iwasawa et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2018)
Structure and dynamics of GPCR signaling complexes
Daniel Hilger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury
Makoto Kurano et al.
THROMBOSIS AND HAEMOSTASIS (2018)
New Insights into Modes of GPCR Activation
Wenjing Wang et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases
Brunilde Gril et al.
NATURE COMMUNICATIONS (2018)
Structure and dynamics of GPCR signaling complexes
Daniel Hilger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Sphingosine-1-Phosphate Receptor 1 Activation Enhances Leptomeningeal Collateral Development and Improves Outcome after Stroke in Mice
Eri Iwasawa et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2018)
Sphingosine 1-Phosphate Receptor 1 Signaling Maintains Endothelial Cell Barrier Function and Protects Against ImmuneComplex-Induced Vascular Injury
Nathalie Burg et al.
ARTHRITIS & RHEUMATOLOGY (2018)
Targeting G protein-coupled receptor signalling by blocking G proteins
Adrian P. Campbell et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
The Various Roles of Fatty Acids
Carla C. C. R. de Carvalho et al.
MOLECULES (2018)
Transcription Factor ETS-1 and Reactive Oxygen Species: Role in Vascular and Renal Injury
Yan-Ting Shiu et al.
ANTIOXIDANTS (2018)
High-Density Lipoprotein-Associated Apolipoprotein M Limits Endothelial Inflammation by Delivering Sphingosine-1-Phosphate to the Sphingosine-1-Phosphate Receptor 1
Mario Ruiz et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2017)
TGF-β Down-regulates Apolipoprotein M Expression through the TAK-1-JNK-c-Jun Pathway in HepG2 Cells
Kun Ren et al.
LIPIDS (2017)
Animal models of atherosclerosis
Besa Emini Veseli et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
G-Protein Dependent Signal Transduction and Ubiquitination in Dictyostelium
Barbara Pergolizzi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes
Stephanie S. Dusaban et al.
JOURNAL OF NEUROINFLAMMATION (2017)
HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium
Mario Ruiz et al.
LIPIDS IN HEALTH AND DISEASE (2017)
Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets
Thiet M. Vu et al.
NATURE (2017)
Trends in GPCR drug discovery: new agents, targets and indications
Alexander S. Hauser et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis
Xiao-Jing Sun et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2017)
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1
Keisuke Yanagida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
Alessandro Cannavo et al.
FRONTIERS IN PHARMACOLOGY (2017)
Sphingosine 1-phosphate receptor 1 (S1PR1) agonist CYM5442 inhibits expression of intracellular adhesion molecule 1 (ICAM1) in endothelial cells infected with influenza A viruses
Hao Jiang et al.
PLOS ONE (2017)
Impairment of blood-brain barrier is an early event in R6/2 mouse model of Huntington Disease
Alba Di Pardo et al.
SCIENTIFIC REPORTS (2017)
A sphingosine-1-phosphate receptor type 1 agonist, ASP4058, suppresses intracranial aneurysm through promoting endothelial integrity and blocking macrophage transmigration
Rie Yamamoto et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Interleukin-27 enhances TNF-α-mediated activation of human coronary artery endothelial cells
Huai-Na Qiu et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2016)
Sphingosine-1-phosphate receptor 2 mediates endothelial cells dysfunction by PI3K-Akt pathway under high glucose condition
Weihua Liu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1
Pernille M. Christensen et al.
FASEB JOURNAL (2016)
A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay
Jonathan K. Fleming et al.
JOURNAL OF LIPID RESEARCH (2016)
Cellular function and signaling pathways of vascular smooth muscle cells modulated by sphingosine 1-phosphate
Takuji Machida et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2016)
Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs
Mitchell K. P. Lai et al.
NEUROMOLECULAR MEDICINE (2016)
The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined
Lei Jin et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2016)
Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors
Rachael Wiltshire et al.
SCIENTIFIC REPORTS (2016)
S1P Signaling and De Novo Biosynthesis in Blood Pressure Homeostasis
Anna Cantalupo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury
Matthew L. Stone et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology
Janelle Drouin-Ouellet et al.
ANNALS OF NEUROLOGY (2015)
The role of serum amyloid A and sphingosine-1-phosphate on high-density lipoprotein functionality
Nicole Pruefer et al.
BIOLOGICAL CHEMISTRY (2015)
Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis
Yu Hisano et al.
GENES TO CELLS (2015)
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders
Adrian D. Hobson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation
Victoria A. Blaho et al.
NATURE (2015)
FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase
Faik Imeri et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2015)
SPHINGOSINE KINASE 2 AND SPHINGOSINE-1-PHOSPHATE PROMOTES MITOCHONDRIAL FUNCTION IN DOPAMINERGIC NEURONS OF MOUSE MODEL OF PARKINSON'S DISEASE AND IN MPP+-TREATED MN9D CELLS IN VITRO
M. Sivasubramanian et al.
NEUROSCIENCE (2015)
HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation
Sylvain Galvani et al.
SCIENCE SIGNALING (2015)
Abluminal Stimulation of Sphingosine 1-Phosphate Receptors 1 and 3 Promotes and Stabilizes Endothelial Sprout Formation
Anusuya Das et al.
TISSUE ENGINEERING PART A (2015)
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
Claudia Nussbaum et al.
NATURE COMMUNICATIONS (2015)
Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke
Gab Seok Kim et al.
NATURE COMMUNICATIONS (2015)
HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation
Sylvain Galvani et al.
SCIENCE SIGNALING (2015)
Differential activation of receptors and signal pathways upon stimulation by different doses of sphingosine-1-phosphate in endothelial cells
Qiang Li et al.
EXPERIMENTAL PHYSIOLOGY (2015)
Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse
Zhen Wang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Host endothelial S1PR1 regulation of vascular permeability modulates tumor growth
Gor Sarkisyan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)
The compensatory enrichment of sphingosine-1-phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 diabetes mellitus
Xunliang Tong et al.
CARDIOVASCULAR DIABETOLOGY (2014)
Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes
Yulia Artemenko et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development
Yuquan Xiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs
Emilie Begagne et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
An update on the biology of sphingosine 1-phosphate receptors
Victoria A. Blaho et al.
JOURNAL OF LIPID RESEARCH (2014)
The Transcription Factor E26 Transformation-Specific Sequence-1 Mediates Neointima Formation in Arteriovenous Fistula
Wenguang Feng et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Sphingosine-1-Phosphate Receptor 3 Mediates Sphingosine-1-Phosphate Induced Release of Weibel-Palade Bodies from Endothelial Cells
Kathinka W. E. M. van Hooren et al.
PLOS ONE (2014)
Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer
Huaqing Cai et al.
SCIENCE (2014)
Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P(1)/S1P(3)-dependent beta-arrestin/c-Src pathways
Jung Min Ryu et al.
STEM CELL RESEARCH (2014)
Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation
Guoqi Zhang et al.
BLOOD (2013)
High-density lipoprotein of patients with Type 2 Diabetes Mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate
Xunliang Tong et al.
CARDIOVASCULAR DIABETOLOGY (2013)
Sphingosine 1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning
Karen Mendelson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation
Christopher S. Garris et al.
NATURE IMMUNOLOGY (2013)
Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis
Anthony O. Awojoodu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells
Wenliang Zhang et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2013)
The Expanding Roles of Gβγ Subunits in G Protein-Coupled Receptor Signaling and Drug Action
Shahriar M. Khan et al.
PHARMACOLOGICAL REVIEWS (2013)
Sphingosine Phosphate Lyase Regulates Murine Embryonic Stem Cell Proliferation and Pluripotency through an S1P2/STAT3 Signaling Pathway
Gaelen S. Smith et al.
BIOMOLECULES (2013)
CCR7 with S1P1 Signaling through AP-1 for Migration of Foxp3+ Regulatory T-Cells Controls Autoimmune Exocrinopathy
Naozumi Ishimaru et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma
Yong Liu et al.
BLOOD (2012)
The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2
Konstantin Gaengel et al.
DEVELOPMENTAL CELL (2012)
Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development
Bongnam Jung et al.
DEVELOPMENTAL CELL (2012)
The functional roles of S1P in immunity
Yu Hisano et al.
JOURNAL OF BIOCHEMISTRY (2012)
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
Shigetomo Fukuhara et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier
Ruben van Doom et al.
JOURNAL OF NEUROINFLAMMATION (2012)
LPS and TNF-α induce expression of sphingosine-1-phosphate receptor-2 in human microvascular endothelial cells
Jing Du et al.
PATHOLOGY RESEARCH AND PRACTICE (2012)
Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway
Kenneth C. Loh et al.
PLOS ONE (2012)
The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate
Alejandra Mendoza et al.
CELL REPORTS (2012)
Neuroplasticity in addiction: cellular and transcriptional perspectives
Heather B. Madsen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
A Sphingosine 1-Phosphate 1 Receptor Agonist Modulates Brain Death-Induced Neurogenic Pulmonary Injury
Saad Sammani et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis
Athanasia Skoura et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection
John R. Teijaro et al.
CELL (2011)
Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors
Victoria A. Blaho et al.
CHEMICAL REVIEWS (2011)
Engagement of S1P1-degradative mechanisms leads to vascular leak in mice
Myat Lin Oo et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
Christina Christoffersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Differential Effects of Sphingosine 1-Phosphate Receptors on Airway and Vascular Barrier Function in the Murine Lung
Saad Sammani et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)
Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease
Katherine J. E. Sattler et al.
BASIC RESEARCH IN CARDIOLOGY (2010)
Transcription factor Ets-1 in cytokine and chemokine gene regulation
Lisa Russell et al.
CYTOKINE (2010)
International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature
Jerold Chun et al.
PHARMACOLOGICAL REVIEWS (2010)
Regulation of Transcription Factors by Heterotrimeric G Proteins
M. Ho et al.
Current Molecular Pharmacology (2010)
Balance of S1P(1) and S1P(2) signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature
Jen-Fu Lee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Sphingosine 1-Phosphate A Regulator of Arterial Lesions
G. Daum et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)
FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system
Volker Brinkmann
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: Role of sphingosine-1-phosphate
Miguel A. Frias et al.
CARDIOVASCULAR RESEARCH (2009)
Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice
Eric Camerer et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Ethanol Augments RANTES/CCL5 Expression in Rat Liver Sinusoidal Endothelial Cells and Human Endothelial Cells via Activation of NF-κB, HIF-1α, and AP-1
Samantha M. Yeligar et al.
JOURNAL OF IMMUNOLOGY (2009)
Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M
Madhumati Sevvana et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Mechanotransduction in vascular physiology and atherogenesis
Cornelia Hahn et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
The vascular S1P gradient - Cellular sources and biological significance
Timothy Hla et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Vascular endothelium as a contributor of plasma sphingosine 1-phosphate
Krishnan Venkataraman et al.
CIRCULATION RESEARCH (2008)
Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells
Mohammad Tauseef et al.
CIRCULATION RESEARCH (2008)
Up-regulating Sphingosine 1-Phosphate Receptor-2 Signaling Impairs Chemotactic, Wound-healing, and Morphogenetic Responses in Senescent Endothelial Cells
Rosendo Estrada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Asymmetric synthesis of conformationally constrained Fingolimod analogues - Discovery of an orally active sphingosine 1-Phosphate receptor type-1 agonist and receptor type-3 antagonist
Ran Zhu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN
Teresa Sanchez et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Constrained azacyclic analogues of the immunomodulatory agent FTY720 as molecular probes for sphingosine 1-phosphate receptors
Stephen Hanessian et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
The nuclear transcription factor CREB: Involvement in addiction, deletion models and looking forward
Cameron S. McPherson et al.
CURRENT NEUROPHARMACOLOGY (2007)
Role of scavenger receptor class B type I and sphingosine 1-phosphate receptors in high density lipoprotein-induced inhibition of adhesion molecule expression in endothelial cells
Takao Kimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor
Angela M. Whetzel et al.
CIRCULATION RESEARCH (2006)
CCL2 regulates angiogenesis via activation of Ets-1 transcription factor
Svetlana M. Stamatovic et al.
JOURNAL OF IMMUNOLOGY (2006)
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
SR Schwab et al.
SCIENCE (2005)
Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling
YM Zhan et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Sphingosine 1-phosphate-related metabolism in the blood vessel
S Aoki et al.
JOURNAL OF BIOCHEMISTRY (2005)
The GRAFS classification system of G-protein coupled receptors in comparative perspective
HB Schiöth et al.
GENERAL AND COMPARATIVE ENDOCRINOLOGY (2005)
Structural and functional characteristics of S1P receptors
T Sanchez et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis
M Kono et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury
XQ Peng et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2004)
Molecular neurobiology of drug addiction
J Chao et al.
ANNUAL REVIEW OF MEDICINE (2004)
Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization
JH Paik et al.
GENES & DEVELOPMENT (2004)
G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation
ML Allende et al.
BLOOD (2003)
The G-protein-coupled receptors in the human genome form five main families.: Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2003)
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
YJ Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)