Dietary and Plasma Phospholipid Profiles in Vegans and Omnivores-Results from the RBVD Study

Over the last few years, the vegan diet has become increasingly popular in Germany. It has been proposed that this diet is generally lower in fat, but less is known about the impact on fatty acid (FA) profiles. Therefore, the cross-sectional Risks and Benefits of a Vegan Diet (RBVD) study (n = 72) was used to investigate dietary FA intake as well as plasma phospholipid FA in vegans (n = 36) compared to omnivores (n = 36). Vegans had a significantly lower dietary intake of total fat (median 86 g/day, IQR 64-111) in comparison to omnivores (median 104 g/day, IQR 88-143, p = 0.004). Further, vegans had a lower intake of saturated fatty acids (SFA) (p < 0.0001) and monounsaturated fatty acids (MUFA) (p = 0.001) compared to omnivores. Vegans had a higher intake in total polyunsaturated fatty acids (PUFA), omega-3 and omega-6 PUFA compared to omnivores, but without statistical significance after Bonferroni correction. According to plasma phospholipid profiles, relatively lower proportions of SFA (p < 0.0001), total trans fatty acids (TFA) (p = 0.0004) and omega-3-FA (p < 0.0001), but higher proportions of omega-6-FA (p < 0.0001) were observed in vegans. With the exception of omega-3 PUFA, a vegan diet is associated with a more favorable dietary fat intake and more favorable plasma FA profiles and therefore may reduce cardiovascular risk.

Automated summary

The vegan diet has gained popularity in Germany in recent years. A study comparing vegans and omnivores found that vegans have a lower intake of total fat, saturated fatty acids, and monounsaturated fatty acids, but higher intake of total polyunsaturated fatty acids, omega-3, and omega-6 fatty acids. Additionally, vegans have more favorable plasma fatty acid profiles, with lower proportions of saturated fatty acids, trans fatty acids, and omega-3 fatty acids, but higher proportions of omega-6 fatty acids. Overall, a vegan diet is associated with a more favorable dietary fat intake and plasma fatty acid profile, which may reduce cardiovascular risk.