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The Effects of Dietary Advanced Glycation End-Products on Neurocognitive and Mental Disorders

NUTRIENTS (2022)

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Diet May Moderate the Relationship Between Arterial Stiffness and Cognitive Performance in Older Adults

Sarah Gauci et al.

Summary: This study examined the inter-relationship between risk factors for cognitive decline (diet, cardiovascular disease, and glucose control) and cognitive performance in older adults. The results showed that diet quality and glucose control were not significantly related to cognitive outcomes, but arterial stiffness was negatively associated with spatial working memory and interacted with diet quality to affect total recall and composite score of verbal learning.

JOURNAL OF ALZHEIMERS DISEASE (2022)

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Article Nutrition & Dietetics

Metabolic Syndrome, Cognitive Impairment and the Role of Diet: A Narrative Review

Matina Kouvari et al.

Summary: This review explores the association between metabolic syndrome and cognitive decline and the potential role of diet in reversing cognitive impairment. Optimizing nutritional intake can reduce the risk factors for both metabolic syndrome and cognitive impairment. The Mediterranean dietary pattern and specific dietary food groups may prevent dementia and other cognition-related disorders.

NUTRIENTS (2022)

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Article Food Science & Technology

Differences in kinetics and dynamics of endogenous versus exogenous advanced glycation end products (AGEs) and their precursors

Katja C. W. van Dongen et al.

Summary: This review investigates the roles of endogenously versus exogenously formed glycation products in the potential induction of adverse health effects. Based on the available data, exogenous low molecular mass glycation products appear to be bioavailable and contribute to dicarbonyl stress and protein cross-linking, resulting in formation of endogenous AGEs. On the other hand, exogenous high molecular mass glycation products have limited bioavailability but can bind to the AGE receptor, initiating adverse health effects. Additionally, effects on gut microbiota induced by glycation products is proposed as another mode of action.

FOOD AND CHEMICAL TOXICOLOGY (2022)

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Review Biochemistry & Molecular Biology

The Role of Advanced Glycation End Products and Its Soluble Receptor in Kidney Diseases

Mieke Steenbeke et al.

Summary: Patients with chronic kidney disease (CKD) are more prone to oxidative stress and chronic inflammation, resulting in increased production and decreased clearance of advanced glycation end products (AGEs). AGEs may contribute to decreased kidney function and increased all-cause mortality in CKD patients. Interaction between AGEs and their cell-bound receptor RAGE activates nuclear factor kappa-B (NF-kappa B), leading to cell dysfunction and increased production of inflammatory cytokines. Alterations in the AGE-RAGE system are associated with the development of various chronic kidney diseases. Soluble RAGE (sRAGE) acts as a decoy receptor to inhibit membrane-bound RAGE activation and AGE-RAGE-related toxicity. The ratio of AGEs to sRAGE may be a useful tool for predicting the prognosis of kidney diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Effect of nutrition on neurodegenerative diseases. A systematic review

Vittorio Emanuele Bianchi et al.

Summary: Neurodegenerative diseases are characterized by the loss of neurons in the brain, and nutrition plays a crucial role in their pathogenesis and development. The Mediterranean diet, nutritional support, and calorie-controlled diets have a protective effect against cognitive decline and diseases like Alzheimer's and Parkinson's, while malnutrition and insulin resistance are significant risk factors.

NUTRITIONAL NEUROSCIENCE (2021)

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The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction

Domenico Sergi et al.

Summary: AGEs are a group of molecules produced through non-enzymatic reactions, implicated in complications of diabetes and metabolic health, contributing to the development of type 2 diabetes and obesity.

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Shawn Hayley et al.

Summary: Major depression may be a precursor to cognitive decline and dementia, with chronic stress and inflammation compromising brain function and leading to depression and mild cognitive impairment. Treating inflammatory changes in depression can reverse the condition, and anti-inflammatory and antidepressant treatments may reduce or prevent dementia in individuals with depression. Chronic stress and inflammation may increase brain permeability and cytokine production, eventually manifesting as depression, cognitive impairment, and potentially dementia.

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Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study

Benjamin Perry et al.

Summary: The study suggests potential causal associations between IL-6 and schizophrenia as well as depression, and highlights the need for replication in larger samples. Some findings did not survive correction for multiple testing, emphasizing the importance of further research in this area.

BRAIN BEHAVIOR AND IMMUNITY (2021)

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Review Nutrition & Dietetics

The Impact of Low Advanced Glycation End Products Diet on Metabolic Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Mohammad Hasan Sohouli et al.

Summary: The study found that a diet low in advanced glycation end products (AGEs) can have beneficial effects on reducing the risk of metabolic syndrome in adults. Specifically, it showed significant reductions in insulin resistance, fasting insulin, total cholesterol, and LDL. Following a low AGEs diet may be a helpful strategy to decrease the burden of metabolic syndrome risk factors, especially in individuals with diabetes.

ADVANCES IN NUTRITION (2021)

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Assessment of Advanced Glycation End Products and Receptors and the Risk of Dementia

Jinluan Chen et al.

Summary: The study found that the AGE-RAGE system is associated with cognitive decline and dementia cross-sectionally but not longitudinally. This suggests a short-term association or reverse causality. Further research is needed to confirm cross-sectional associations between higher skin autofluorescence and cognitive function, as well as the association with APOE status.

JAMA NETWORK OPEN (2021)

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Review Biochemistry & Molecular Biology

Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease

Mohamed Haddad et al.

Summary: Glutathione plays a significant role as an antioxidant in the brain related to Alzheimer's disease, with alterations in its levels correlated with cognitive decline. Strategies have been developed to restore its intracellular level, but no significant benefits have been reported in clinical trials so far. Future directions include utilizing GSH-coupled nanocarriers for brain delivery and investigating its presence in exosomes for potential intercellular transfer.

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Article Clinical Neurology

Skin autofluorescence of advanced glycation end products and mortality in affective disorders in the lifelines cohort study: A mediation analysis

Julia M. Hagen et al.

Summary: The study showed evidence of partial mediation by skin autofluorescence in the association between affective disorders and all-cause and natural-cause mortality, although attenuated by health factors. The largest mediation by SAF was observed for major depression, which remained significant even after adjustments for sociodemographic and health factors, indicating oxidative stress as a possible determinant of premature death.

JOURNAL OF AFFECTIVE DISORDERS (2021)

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Review Nutrition & Dietetics

Diet and the Microbiota-Gut-Brain Axis: Sowing the Seeds of Good Mental Health

Kirsten Berding et al.

Summary: Recent research has highlighted the important role of diet in influencing brain function and behavior through modulation of the gut microbiota. Animal studies have identified various mechanisms of communication between the gut and brain, emphasizing the impact of diet on this process. While promising results have been reported, further data from clinical populations are needed to advance the development of microbiota-targeted dietary strategies for improving brain and mental health.

ADVANCES IN NUTRITION (2021)

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Article Multidisciplinary Sciences

Oxidative stress and soluble receptor for advanced glycation end-products play a role in the pathophysiology of delirium after cardiac surgery

Jakub Kazmierski et al.

Summary: This study investigated the relationship between decreased preoperative and postoperative plasma antioxidant activity and delirium after cardiac surgery, finding that low baseline antioxidant capacity was independently associated with postoperative delirium development. Additionally, preoperative diagnosis of MDD and decreased antioxidant activity were also associated with an increased risk of delirium. sRAGE overexpression may be considered a protective mechanism against oxidative stress and cell damage.

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Dysbiosis-Related Advanced Glycation Endproducts and Trimethylamine N-Oxide in Chronic Kidney Disease

Kensei Taguchi et al.

Summary: Chronic kidney disease affects approximately 10% of the global population and is associated with high frequencies of comorbidities such as heart failure and cardiovascular disease. Gut microbial dysbiosis, an imbalance of the gut microbial community, accelerates CKD progression by producing more uremic toxins in the gastrointestinal tracts. The gut-kidney axis has emerged as a potential therapeutic target for treating CKD.

TOXINS (2021)

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Novel advances in inhibiting advanced glycation end product formation using natural compounds

Qinghe Song et al.

Summary: This paper discusses the formation, classification, and effects of AGEs on human health, with a focus on natural compounds as inhibitors of AGE formation. Major classes of natural inhibitors, including polyphenols, polysaccharides, terpenoids, vitamins, and alkaloids, have been described, with mechanisms of action ranging from scavenging free radicals to lowering blood glucose levels. These natural compounds, despite not being widely used clinically due to their low content levels, will be valuable in inspiring drug discovery.

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Effect of Advanced Glycation End Products on Cognition in Older Adults with Type 2 Diabetes: Results from a Pilot Clinical Trial

Roni Lotan et al.

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JOURNAL OF ALZHEIMERS DISEASE (2021)

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Article Psychiatry

Advanced glycation end products measured by skin autofluorescence are associated with melancholic depressive symptoms - Findings from Helsinki Birth Cohort Study

Mia D. Eriksson et al.

Summary: This study found an association between depressive symptoms and higher AGE levels, which is likely part of a multi-factorial effect. Therefore, no directionality, causality, or effect can be inferred solely based on the results of this study.

JOURNAL OF PSYCHOSOMATIC RESEARCH (2021)

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Advanced glycation end products and cognitive impairment in schizophrenia

Akiko Kobori et al.

Summary: Advanced glycation end products were found to impact the cognitive domain of patients with schizophrenia, with processing speed being the main affected area. Previous research has shown that impaired processing speed is related to poor functional outcomes, so interventions aimed at reducing advanced glycation end products may help improve recovery and cognitive function in patients with schizophrenia.

PLOS ONE (2021)

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Review Nutrition & Dietetics

Dietary AGEs as Exogenous Boosters of Inflammation

Ma. Eugenia Garay-Sevilla et al.

Summary: Many chronic diseases seem to be caused by prolonged low-grade inflammation, with diet playing a crucial role in creating and sustaining this state, especially through pro-inflammatory compounds like advanced glycation end products (AGEs) formed during thermal processing. Studies suggest a significant association between dietary intake of AGEs and the development of inflammation and oxidative stress conducive to chronic diseases.

NUTRIENTS (2021)

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Review Nutrition & Dietetics

Circulating Advanced Glycation End Products and Their Soluble Receptors in Relation to All-Cause and Cardiovascular Mortality: A Systematic Review andMeta-analysis of Prospective Observational Studies

Elham Sharifi-Zahabi et al.

Summary: Our meta-analysis showed that higher serum AGE concentration was associated with increased risk of all-cause and CVD mortality. Additionally, higher circulating sRAGE levels were also linked to an increased risk of CVD mortality.

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Fingertip advanced glycation end products and psychotic symptoms among adolescents

Mitsuhiro Miyashita et al.

Summary: This study found that fingertip advanced glycation end products could predict the trajectory of psychotic symptoms in drug-naive adolescents, indicating its involvement in the pathophysiology of early psychosis. Further research is needed to identify strategies to reduce adolescent advanced glycation end products, which may help prevent the onset of psychosis.

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Melissa M. Lane et al.

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Use of skin advanced glycation end product levels measured using a simple noninvasive method as a biological marker for the diagnosis of neuropsychiatric diseases

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High Dietary Advanced Glycation End Products Impair Mitochondrial and Cognitive Function

Firoz Akhter et al.

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Advanced Glycation End Products Modulate Amyloidogenic APP Processing and Tau Phosphorylation: A Mechanistic Link between Glycation and the Development of Alzheimer's Disease

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Dietary Advanced Glycation Endproducts Induce an Inflammatory Response in Human Macrophages in Vitro

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Advanced Glycation End Product (AGE) Accumulation in the Skin is Associated with Depression: The Maastricht Study

Fleur E. P. van Dooren et al.

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Samer Hammoudeh et al.

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Advanced Glycation End Products in Recent-Onset Psychosis Indicate Early Onset of Cardiovascular Risk

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Salvatore Bongarzone et al.

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Dietary advanced glycation end products modify gut microbial composition and partially increase colon permeability in rats

Wanting Qu et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2017)

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High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes

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High dietary advanced glycation end products are associated with poorer spatial learning and accelerated A deposition in an Alzheimer mouse model

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Review Nutrition & Dietetics

Dietary Advanced Glycation End Products and Their Role in Health and Disease

Jaime Uribarri et al.

ADVANCES IN NUTRITION (2015)

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Article Multidisciplinary Sciences

The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease

Shun-Yao Ko et al.

PLOS ONE (2015)

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Review Biochemistry & Molecular Biology

Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus

Kerstin Nowotny et al.

BIOMOLECULES (2015)

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Article Medical Laboratory Technology

Peripheral blood lymphocytes from patients with bipolar disorder demonstrate apoptosis and differential regulation of advanced glycation end products and S100B

Paraskevi Moutsatsou et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2014)

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Article Endocrinology & Metabolism

Advanced Glycation End Products (AGE) and Diabetes: Cause, Effect, or Both?

Helen Vlassara et al.

CURRENT DIABETES REPORTS (2014)

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Review Pharmacology & Pharmacy

Advanced Glycation End Products and Diabetic Complications

Varun Parkash Singh et al.

KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY (2014)

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Article Food Science & Technology

Maillard reaction products modulate gut microbiota composition in adolescents

Isabel Seiquer et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2014)

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Article Cell Biology

Dietary advanced glycation end products are associated with decline in memory in young elderly

Rebecca K. West et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2014)

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Review Endocrinology & Metabolism

Vascular effects of advanced glycation endproducts: Clinical effects and molecular mechanisms

Alin Stirban et al.

MOLECULAR METABOLISM (2014)

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Review Biochemistry & Molecular Biology

Role of advanced glycation end products in cellular signaling

Christiane Ott et al.

REDOX BIOLOGY (2014)

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Article Medicine, Research & Experimental

Inhibitory effect of soluble RAGE in disturbed flow-induced atherogenesis

Chang Hoon Ha et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2013)

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Review Cell Biology

RAGE regulation and signaling in inflammation and beyond

Katrin Kierdorf et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2013)

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Article Clinical Neurology

Higher glucose levels associated with lower memory and reduced hippocampal microstructure

Lucia Kerti et al.

NEUROLOGY (2013)

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Review Neurosciences

Gut-brain: how the microbiome influences anxiety and depression

Jane A. Foster et al.

TRENDS IN NEUROSCIENCES (2013)

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Article Clinical Neurology

Mitochondrial dysfunction, oxidative stress, and major depressive disorder

Edward H. Tobe

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2013)

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Article Dermatology

Ethnic and gender differences in advanced glycation end products measured by skin auto-fluorescence

Marjonneke J. Mook-Kanamori et al.

DERMATO-ENDOCRINOLOGY (2013)

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Article Biochemistry & Molecular Biology

Study of the urinary and faecal excretion of N ε-carboxymethyllysine in young human volunteers

Cristina Delgado-Andrade et al.

AMINO ACIDS (2012)

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Article Cell Biology

Mechanistically linking age-related diseases and dietary carbohydrate via autophagy and the ubiquitin proteolytic systems

Allen Taylor

AUTOPHAGY (2012)

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Article Medical Laboratory Technology

EN-RAGE (extracellular newly identified receptor for advanced glycation end-products binding protein) and mortality of long-term hemodialysis patients: A prospective observational cohort study

Marta Kalousova et al.

CLINICAL BIOCHEMISTRY (2012)

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Article Endocrinology & Metabolism

Association Between Serum Endogenous Secretory Receptor for Advanced Glycation End Products and Risk of Type 2 Diabetes Mellitus with Combined Depression in the Chinese Population

Gang Chen et al.

DIABETES TECHNOLOGY & THERAPEUTICS (2012)

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Review Clinical Neurology

Advanced glycation end products and neurodegenerative diseases: Mechanisms and perspective

Jinlong Li et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2012)

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Article Geriatrics & Gerontology

AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation

Xiao-Hong Li et al.

NEUROBIOLOGY OF AGING (2012)

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Article Food Science & Technology

Natural inhibitors of advanced glycation end-products

J. S. Ramkissoon et al.

NUTRITION & FOOD SCIENCE (2012)

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Article Neurosciences

Depression, Anxiety, and Arterial Stiffness

Adrie Seldenrijk et al.

BIOLOGICAL PSYCHIATRY (2011)

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Article Immunology

AGE-RAGE in Multiple Sclerosis Brain

Zohara Sternberg et al.

IMMUNOLOGICAL INVESTIGATIONS (2011)

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Review Neurosciences

Role of Advanced Glycation on Aggregation and DNA Binding Properties of α-Synuclein

Vasudevaraju Padmaraju et al.

JOURNAL OF ALZHEIMERS DISEASE (2011)

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Article Urology & Nephrology

Benfotiamine Protects against Peritoneal and Kidney Damage in Peritoneal Dialysis

Lars P. Kihm et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

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Editorial Material Clinical Neurology

Advanced glycation end products, diabetes, and the brain

Laura H. Coker et al.

NEUROLOGY (2011)

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Article Clinical Neurology

Advanced glycation end product level, diabetes, and accelerated cognitive aging

K. Yaffe et al.

NEUROLOGY (2011)

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Article Neurosciences

Serum levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with different psychiatric disorders

Enzo Emanuele et al.

NEUROSCIENCE LETTERS (2011)

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Review Psychology, Clinical

Prevalence and clinical course of depression: A review

Derek Richards

CLINICAL PSYCHOLOGY REVIEW (2011)

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Article Pharmacology & Pharmacy

Soluble RAGE: Therapy and biomarker in unraveling the RAGE axis in chronic disease and aging

Shi Fang Yan et al.

BIOCHEMICAL PHARMACOLOGY (2010)

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Article Biochemistry & Molecular Biology

RAGE-dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease

Fang Fang et al.

FASEB JOURNAL (2010)

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Article Agriculture, Multidisciplinary

Effect of Inhibitor Compounds on Nε-(Carboxymethyl)lysine (CML) and Nε-(Carboxyethyl)lysine (CEL) Formation in Model Foods

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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)

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Article Nutrition & Dietetics

Advanced Glycation End Products in Foods and a Practical Guide to Their Reduction in the Diet

Jaime Uribarri et al.

JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION (2010)

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Article Geriatrics & Gerontology

Does Accumulation of Advanced Glycation End Products Contribute to the Aging Phenotype?

Richard D. Semba et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2010)

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Article Neurosciences

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

Tony Valente et al.

NEUROBIOLOGY OF DISEASE (2010)

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Article Pathology

Advanced Glycation End Product Receptor-1 Transgenic Mice Are Resistant to Inflammation, Oxidative Stress, and Post-Injury Intimal Hyperplasia

Massimo Torreggiani et al.

AMERICAN JOURNAL OF PATHOLOGY (2009)

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Review Clinical Neurology

Brain-derived neurotrophic factor in neurodegenerative diseases

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NATURE REVIEWS NEUROLOGY (2009)

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Article Multidisciplinary Sciences

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

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Article Endocrinology & Metabolism

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs

Christos Tikellis et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)

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Review Pharmacology & Pharmacy

Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease

Masayoshi Takeuchi et al.

CURRENT PHARMACEUTICAL DESIGN (2008)

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Article Biochemistry & Molecular Biology

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

Angela Raucci et al.

FASEB JOURNAL (2008)

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Review Endocrinology & Metabolism

The role of advanced glycation end products in progression and complications of diabetes

Su-Yen Goh et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)

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Article Neurosciences

Advanced glycation end products induce in vitro cross-linking of α-synuclein and accelerate the process of intracellular inclusion body formation

Shamim Shaikh et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2008)

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Article Clinical Neurology

Soluble receptor for advanced glycation end products in multiple sclerosis: A potential marker of disease severity

Z. Sternberg et al.

MULTIPLE SCLEROSIS JOURNAL (2008)

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Article Geriatrics & Gerontology

Advanced glycation end products, diabetes and ageing

N. Nass et al.

ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE (2007)

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Article Neurosciences

New insights into BDNF function in depression and anxiety

Keri Martinowich et al.

NATURE NEUROSCIENCE (2007)

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Article Geriatrics & Gerontology

Circulating glycotoxins and dietary advanced glycation endproducts: Two links to inflammatory response, oxidative stress, and aging

Jaime Uribarri et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2007)

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Article Peripheral Vascular Disease

Advanced glycation end-products and arterial stiffness in hypertension

Marie McNulty et al.

AMERICAN JOURNAL OF HYPERTENSION (2007)

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Article Endocrinology & Metabolism

Skin autofluorescence, a novel marker for glycemic and oxidative stress-derived advanced glycation endproducts: An overview of current clinical studies, evidence, and limitations

Douwe J. Mulder et al.

DIABETES TECHNOLOGY & THERAPEUTICS (2006)

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Review Cardiac & Cardiovascular Systems

Advanced glycation end products - Sparking the development of diabetic vascular injury

Alison Goldin et al.

CIRCULATION (2006)

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Article Hematology

Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis

H Koyama et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)

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Review Biochemistry & Molecular Biology

Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation

R Ramasamy et al.

GLYCOBIOLOGY (2005)

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Article Agriculture, Multidisciplinary

Inhibitory effect of naturally occurring flavonoids on the formation of advanced glycation endproducts

CH Wu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2005)

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Article Rheumatology

Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis

J DeGroot et al.

ARTHRITIS AND RHEUMATISM (2004)

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Article Nutrition & Dietetics

Advanced glycoxidation end products in commonly consumed foods

T Goldberg et al.

JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION (2004)

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Article Biochemistry & Molecular Biology

Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

S Prabakaran et al.

MOLECULAR PSYCHIATRY (2004)

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Article Endocrinology & Metabolism

Simple non-invasive assessment of advanced glycation endproduct accumulation

R Meerwaldt et al.

DIABETOLOGIA (2004)

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Article Biochemistry & Molecular Biology

Identification of enzymes acting on α-glycated amino acids in Bacillus subtilis

E Wiame et al.

FEBS LETTERS (2004)

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Review Immunology

RAGE (receptor for advanced glycation end products): a central player in the inflammatory response

T Chavakis et al.

MICROBES AND INFECTION (2004)

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Article Biochemistry & Molecular Biology

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

R Deane et al.

NATURE MEDICINE (2003)

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Article Biochemistry & Molecular Biology

Maillard reaction products in tissue proteins: New products and new perspectives

SR Thorpe et al.

AMINO ACIDS (2003)

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Article Biochemistry & Molecular Biology

Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli

E Wiame et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

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Article Nutrition & Dietetics

Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet

K Sebeková et al.

EUROPEAN JOURNAL OF NUTRITION (2001)

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Article Biochemistry & Molecular Biology

Crosslinking of α-synuclein by advanced glycation endproducts -: an early pathophysiological step in Lewy body formation?

G Münch et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2000)

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