期刊
NUTRIENTS
卷 14, 期 15, 页码 -出版社
MDPI
DOI: 10.3390/nu14153153
关键词
vitamin D; pediatric obesity; anthropometry; body composition; adiposity
资金
- Dairy Research Cluster Initiative (Agriculture and Agri-Food Canada)
- Dairy Research Cluster Initiative (Dairy Farmers of Canada)
- Dairy Research Cluster Initiative (Canadian Dairy Commission)
This study aimed to examine the association between body composition and vitamin D status. The results showed that vitamin D deficiency was not present in children aged 6-12 with obesity. The study also found that reductions in adiposity did not alter the vitamin D status.
Background: To examine associations between body composition and vitamin D status in children participating in a lifestyle intervention. Methods: Children (6-12 y, n = 101) with a body mass index (BMI)-for-age >85th percentile were randomized to six dietitian-led behavior counselling sessions or no intervention. Plasma 25-hydroxyvitamin D (25(OH)D), anthropometry, and body composition using dual-energy X-ray absorptiometry were assessed every 3 months for 1 year. For each anthropometry variable (z-scores), tertiles were created to test for differences in 25(OH)D over time (tertile-by-time), and for changes in the z-score (loss, maintain, gain)-by-time, and according to fat patterning (android vs. gynoid) using mixed effects models. Results: The baseline plasma 25(OH)D was 62.2 nmol/L (95%CI: 58.7-65.7), and none < 30 nmol/L. At 6 mo, children with gynoid fat patterning had higher 25(OH)D concentrations than in those with android fat patterning (64.5 +/- 1.1 nmol/L vs. 50.4 +/- 1.0 nmol/L, p < 0.003, Cohen's f = 0.20). Children with the lowest lean mass index z-score at 9 mo had higher plasma 25(OH)D concentrations than children with the highest z-score at baseline, 3 mo, and 6 mo (p < 0.05, Cohen's f = 0.20). No other significant differences were observed. Conclusion: In this longitudinal study, vitamin D deficiency was not present in children 6-12 y of age with obesity. Reductions in adiposity did not alter the vitamin D status.
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