4.6 Article

Dielectric property measurement of human sweat using attenuated total reflection terahertz time domain spectroscopy

期刊

BIOMEDICAL OPTICS EXPRESS
卷 13, 期 9, 页码 4572-4582

出版社

Optica Publishing Group
DOI: 10.1364/BOE.467450

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资金

  1. Japan Society [21K04174]
  2. Hamamatsu Foundation for Science and Technology Promotion [2072]
  3. Shizuoka University
  4. Karlsruhe Institute of Technology

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This study utilized attenuated total reflection terahertz time domain spectroscopy to analyze the dielectric properties of human sweat. The results showed that the dielectric permittivity decreases with the increase in frequency, with relaxation processes related to sodium and calcium ions concentrations. These findings are significant for the design of new biosensors, understanding human health conditions, and hydration assessment.
Sweat is one of the essential biofluids produced by the human body, and it contains various physiological biomarkers. These biomarkers can indicate human health conditions such as disease and illness. In particular, imbalances in the concentration of electrolytes can indicate the onset of disease. These same imbalances affect the dielectric properties of sweat. In this study, we used attenuated total reflection terahertz time domain spectroscopy to obtain the frequency-dependent dielectric properties of human sweat in a frequency range from 200 GHz to 2.5 THz. We have investigated the variation of dielectric properties of sweat collected from different regions of the human body, and we have observed that the real and imaginary part of dielectric permittivity decreases with the increase in frequency. A combination of left-hand Jonscher and Havriliak-Negami processes is used to model the results and reveal the presence of relaxation processes related to sodium and calcium ions concentrations. This information may help design novel biosensors to understand the human health condition and provide a hydration assessment.

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