Photoinduced Dynamic Radical Processes for Isomerizations, Deracemizations, and Dynamic Kinetic Resolutions

Isomerizations are chemical processes where a compound is transformed into another structure while retaining the same chemical formula. When dynamic, these reactions are amenable to convergent synthetic scenarios where one isomer reacts preferentially in a subsequent chemical step or accumulates as a function of the isomerization mechanism. With the recent renaissance of photochemistry, there has been a dramatic increase in the number of transformations leveraging radicals and diradicals as key intermediates for isomerization. This perspective will examine these dynamic approaches in isomerizations, deracemizations, and dynamic kinetic resolutions. By better understanding the mechanisms these approaches employ, dynamic processes can be imagined that could streamline chemical synthesis.

Automated summary

This article mainly introduces the isomerization process in chemical reactions, where a compound is transformed into another structure while maintaining the same chemical formula. With the development of photochemistry, there has been an increasing number of isomerization reactions leveraging radicals and diradicals as key intermediates. The article also explores dynamic approaches such as isomerizations, deracemizations, and dynamic kinetic resolutions.