期刊
NATURE COMMUNICATIONS
卷 13, 期 1, 页码 -出版社
NATURE PORTFOLIO
DOI: 10.1038/s41467-022-30833-3
关键词
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资金
- University of Illinois at Urbana-Champaign
- CIMIT through the POCTRN program
- National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Department of Health and Human Services [U54EB015408]
- University of Illinois System Office
- Office of the Vice-Chancellor for Research and Innovation
- Grainger College of Engineering
- United States Department of Energy Computational Science Graduate Fellowship [DE-FG02-97ER25308]
- NSF CAREER Award [1753249]
- U.S. DOE Office of Science Facility, at Brookhaven National Laboratory [DE-SC0012704]
- National Institute for Biomedical Imaging and Bioengineering, National Institutes of Health [U54EB027690]
- RADx Tech program
- Department of Physics at the University of Illinois at Urbana-Champaign
- Division Of Earth Sciences
- Directorate For Geosciences [1753249] Funding Source: National Science Foundation
This study reports on a case study at the University of Illinois at Urbana-Champaign, where a program of public health measures and other non-pharmaceutical interventions were employed to keep classrooms and laboratories open during the COVID-19 pandemic. The results showed that fast/frequent testing and other interventions helped mitigate transmission of SARS-CoV-2 at the university.
In Fall 2020, universities saw extensive transmission of SARS-CoV-2 among their populations, threatening health of the university and surrounding communities, and viability of in-person instruction. Here we report a case study at the University of Illinois at Urbana-Champaign, where a multimodal SHIELD: Target, Test, and Tell program, with other non-pharmaceutical interventions, was employed to keep classrooms and laboratories open. The program included epidemiological modeling and surveillance, fast/frequent testing using a novel low-cost and scalable saliva-based RT-qPCR assay for SARS-CoV-2 that bypasses RNA extraction, called covidSHIELD, and digital tools for communication and compliance. In Fall 2020, we performed >1,000,000 covidSHIELD tests, positivity rates remained low, we had zero COVID-19-related hospitalizations or deaths amongst our university community, and mortality in the surrounding Champaign County was reduced more than 4-fold relative to expected. This case study shows that fast/frequent testing and other interventions mitigated transmission of SARS-CoV-2 at a large public university. Safely opening university campuses has been a major challenge during the COVID-19 pandemic. Here, the authors describe a program of public health measures employed at a university in the United States which, combined with other non-pharmaceutical interventions, allowed the university to stay open in fall 2020 with limited evidence of transmission.
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