Dynamics and Determinants of SARS-CoV-2 RT-PCR Testing on Symptomatic Individuals Attending Healthcare Centers during 2020 in Bahia, Brazil

Editorial Material Infectious Diseases

COVID-19 in Brazil: 150,000 deaths and the Brazilian underreporting

Tatiana Aline Carvalho et al.

Summary: Brazil is experiencing a 22% increase in excess mortality due to COVID-19 pandemic, with male patients and individuals over 60 years old being mainly affected.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2021)

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Review Microbiology

Characteristics of SARS-CoV-2 and COVID-19

Ben Hu et al.

Summary: This review summarizes the research progress on SARS-CoV-2 and COVID-19, including virology characteristics, pathogenesis, and recent advances in treatment methods. Furthermore, it discusses in detail the potential wildlife hosts and zoonotic origin of this emerging virus.

NATURE REVIEWS MICROBIOLOGY (2021)

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Article Psychiatry

COVID-19 and mental health in Brazil: Psychiatric symptoms in the general population

Jeferson Ferraz Goularte et al.

Summary: An investigation on the occurrence and determinants of psychiatric symptoms among the Brazilian general population revealed high prevalence of anxiety, depression, anger, somatic symptoms, and sleep problems. Factors such as younger age, female gender, low income, lower level of education, longer period of social distancing, and history of previous psychiatric illness were strongly associated with higher severity of symptoms. This highlights the urgent need for specific interventions to address the mental health impact of the COVID-19 pandemic in Brazil.

JOURNAL OF PSYCHIATRIC RESEARCH (2021)

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Editorial Material Medicine, General & Internal

SARS-CoV-2 variants and ending the COVID-19 pandemic

Arnaud Fontanet et al.

LANCET (2021)

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Editorial Material Medicine, General & Internal

Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence

Ester C. Sabino et al.

LANCET (2021)

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Review Chemistry, Physical

Diagnostics for SARS-CoV-2 infections

Bhavesh D. Kevadiya et al.

Summary: The outbreak of SARS-CoV-2 causing COVID-19 has led to diverse and severe symptoms, making accurate diagnosis a key challenge. Rapid diagnosis and treatment measures are crucial in controlling the spread of the virus. The development of diagnostic tools, including nanomaterial-based ones, is essential in the fight against the pandemic.

NATURE MATERIALS (2021)

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Article Multidisciplinary Sciences

Molecular testing and analysis of disease spreading during the emergence of COVID-19 in Macae, the Brazilian National Capital of Oil

Natalia Martins Feitosa et al.

Summary: The Brazilian strategy to control the spread of COVID-19 has been criticized for the lack of national coordination and testing programs. In Macae, Brazil, a successful approach was achieved by engaging public and private sectors, leading to effective control of COVID-19 transmission and lower fatality rates compared to other cities in the state. Comprehensive testing, spatial analysis, and prompt notification were key factors in preventing catastrophic consequences of the pandemic in Macae.

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Article Public, Environmental & Occupational Health

How many more? Under-reporting of the COVID-19 deaths in Brazil in 2020

Emil Kupek

Summary: This study evaluated the under-reporting of COVID-19 deaths in Brazil in 2020, revealing a 22.62% underestimation and the significant impact of COVID-19 on mortality in Brazil. Underestimation of COVID-19 mortality may be between 1:5 and 1:4, underscoring the importance of timely and accurate surveillance of death causes.

TROPICAL MEDICINE & INTERNATIONAL HEALTH (2021)

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News Item Medicine, General & Internal

Covid-19: Brazil's spiralling crisis is increasingly affecting young people

Luke Taylor

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Psychiatry

Under-Reporting of COVID-19 Cases Among Indigenous Peoples in Brazil: A New Expression of Old Inequalities

Martha Fellows et al.

Summary: The study revealed that the incidence and mortality rates of COVID-19 among Indigenous Peoples in the Brazilian Amazon are significantly higher than the national average, and there is underreporting of data by the federal government. Additionally, it was found that illegal economic activities increase the risk of spreading COVID-19 in Indigenous Lands.

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Article Public, Environmental & Occupational Health

Higher risk of death from COVID-19 in low-income and non-White populations of SAo Paulo, Brazil

Sabrina L. Li et al.

Summary: In São Paulo state, Brazil, low-income, Black, and Pardo communities are more likely to die from COVID-19, attributed to differential access to quality healthcare, ability to self-isolate, and higher prevalence of comorbidities.

BMJ GLOBAL HEALTH (2021)

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Article Multidisciplinary Sciences

COVID-19 in Brazilian cities: Impact of social determinants, coverage and quality of primary health care

Marcello Barbosa Otoni Goncalves Guedes et al.

Summary: The study shows that greater Primary Health Care and Family Health Strategy coverage, along with higher scores in the National Program for Improving Primary Care Access and Quality (PMAQ), are associated with slower dissemination and lower burden of COVID-19. Cities with less social inequality and restrictions of social protection combined with social development have a milder pandemic scenario.

PLOS ONE (2021)

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Article Multidisciplinary Sciences

Impact of COVID-19 on older adults and role of long-term care facilities during early stages of epidemic in Italy

Stefano Amore et al.

Summary: The study highlights the strong correlation between increased mortality rates in older adults over 80 and Long Term Care Facilities (LTCFs) during the early stages of the COVID-19 outbreak in Italy. Despite the incidence rate of COVID-19, the impact on mortality varied significantly among regions, showing that LTCFs did not act as a protective barrier for the elderly. Inefficient crisis management in LTCFs hindered effective tracing of COVID-19 spread and led to increased deaths unrelated to the SARS-CoV-2 virus.

SCIENTIFIC REPORTS (2021)

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Review Biochemistry & Molecular Biology

COVID-19 in early 2021: current status and looking forward

Chengdi Wang et al.

Summary: Since the first description of a coronavirus-related pneumonia outbreak in December 2019, the virus SARS-CoV-2 has evolved into a pandemic, affecting over 100 million people globally. This review summarized the current knowledge in epidemiology, virology, diagnosis, treatment, and vaccine development, providing specific dates for key developments. The world is working together to combat this pandemic, highlighting the rapid evolution of research and development in these areas.

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Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR

Victor M. Corman et al.

EUROSURVEILLANCE (2020)

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A pneumonia outbreak associated with a new coronavirus of probable bat origin

Peng Zhou et al.

NATURE (2020)

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Routes for COVID-19 importation in Brazil

Darlan Da S. Candido et al.

JOURNAL OF TRAVEL MEDICINE (2020)

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Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

Jian-Min Jin et al.

FRONTIERS IN PUBLIC HEALTH (2020)

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The impact of COVID-19 on people with diabetes in Brazil

Mark Thomaz Ugliara Barone et al.

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Article Public, Environmental & Occupational Health

Ethnic and regional variations in hospital mortality from COVID-19 in Brazil: a cross-sectional observational study

Pedro Baqui et al.

LANCET GLOBAL HEALTH (2020)

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Article Microbiology

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT-qPCR primer-probe sets

Chantal B. F. Vogels et al.

NATURE MICROBIOLOGY (2020)

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Letter Immunology

Immunologic Features in Coronavirus Disease 2019: Functional Exhaustion of T Cells and Cytokine Storm

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Review Medicine, General & Internal

Molecular and Serological Tests for COVID-19. A Comparative Review of SARS-CoV-2 Coronavirus Laboratory and Point-of-Care Diagnostics

Robert Kubina et al.

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COVID-19 Mortality Underreporting in Brazil: Analysis of Data From Government Internet Portals

Lena Veiga e Silva et al.

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COVID-19 in children: the link in the transmission chain

Alyson A. Kelvin et al.

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Article Multidisciplinary Sciences

Evolution and epidemic spread of SARS-CoV-2 in Brazil

Darlan S. Candido et al.

SCIENCE (2020)

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Article Multidisciplinary Sciences

City size and the spreading of COVID-19 in Brazil

Haroldo Ribeiro et al.

PLOS ONE (2020)

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Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR

Ioanna Smyrlaki et al.

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Impact on Mental Health Due to COVID-19 Pandemic: Cross-Sectional Study in Portugal and Brazil

Ligia Passos et al.

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Human development, social vulnerability and COVID-19 in Brazil: a study of the social determinants of health

Carlos Dornels Freire de Souza et al.

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Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR

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Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

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Assessment of patients with Covid-19 hospitalized in southern Santa Catarina

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SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys

Pedro C. Hallal et al.

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Taking the inner route: spatial and demographic factors affecting vulnerability to COVID-19 among 604 cities from inner Sao Paulo State, Brazil

C. M. C. B. Fortaleza et al.

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The ongoing COVID-19 epidemic in Minas Gerais, Brazil: insights from epidemiological data and SARS-CoV-2 whole genome sequencing

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Dynamics and Determinants of SARS-CoV-2 RT-PCR Testing on Symptomatic Individuals Attending Healthcare Centers during 2020 in Bahia, Brazil

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