Isothermal amplification-mediated lateral flow biosensors for in vitro diagnosis of gastric cancer-related microRNAs

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Microfluidic device for one-step detection of breast cancer-derived exosomal mRNA in blood using signal-amplifiable 3D nanostructure

Jaewoo Lim et al.

Summary: The newly developed exoNA-sensing chip, based on microfluidic and 3D-nanostructured hydrogels, allows for rapid detection of ERBB2 with high accuracy and selectivity.

BIOSENSORS & BIOELECTRONICS (2022)

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Article Chemistry, Multidisciplinary

Simultaneous Dual-Gene Diagnosis of SARS-CoV-2 Based on CRISPR/Cas9-Mediated Lateral Flow Assay

Erhu Xiong et al.

Summary: The newly developed method can simultaneously detect two SARS-CoV-2 genes in a single test, showing high sensitivity and accuracy, providing a more accurate and convenient pathway for COVID-19 diagnosis in low-resource regions.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

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Review Oncology

Circulating platelets as liquid biopsy sources for cancer detection

Mafalda Antunes-Ferreira et al.

Summary: Nucleic acids and proteins released by tumor cells into the bloodstream can serve as biomarkers for cancer detection. Platelets, as a rich source of potential cancer biomarkers, have been increasingly recognized for their ability to take up and process these biomolecules. While several studies support the use of platelet biomarkers in cancer diagnostics, there are still limitations in their implementation into clinical practice.

MOLECULAR ONCOLOGY (2021)

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Review Chemistry, Analytical

Rapid developments in lateral flow immunoassay for nucleic acid detection

Chujun Zheng et al.

Summary: This review discusses two main research directions of lateral flow nucleic acid tests, one involving the incorporation of isothermal amplification methods for increased sensitivity, and the other focusing on the development of novel labeling materials for improved quantifiability. Future research will focus on integrating the entire testing process into microfluidic systems and combining with molecular diagnostic tools to facilitate rapid and accurate testing.

ANALYST (2021)

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Article Materials Science, Multidisciplinary

Rapid and sensitive detection of dual lung cancer-associated miRNA biomarkers by a novel SERS-LFA strip coupling with catalytic hairpin assembly signal amplification

Xiaowei Cao et al.

Summary: A novel SERS-LFA biosensor combined with CHA signal amplification was developed for rapid, sensitive, specific, and simultaneous detection of miR-196a-5p and miR-31-5p associated with lung cancer. The biosensor exhibited excellent performance and showed promising potential for early diagnosis and prevention of lung cancer.

JOURNAL OF MATERIALS CHEMISTRY C (2021)

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Article Cell Biology

Novel miRNA markers for the diagnosis and prognosis of endometrial cancer

Qian Wang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

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Article Biotechnology & Applied Microbiology

CRISPR-Cas12-based detection of SARS-CoV-2

James P. Broughton et al.

NATURE BIOTECHNOLOGY (2020)

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Article Immunology

Development and Validation of a Rapid, Single-Step Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) System Potentially to Be Used for Reliable and High-Throughput Screening of COVID-19

Minghua Jiang et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

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Article Microbiology

Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT-qPCR primer-probe sets

Chantal B. F. Vogels et al.

NATURE MICROBIOLOGY (2020)

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Article Biophysics

Urinary exosomal mRNA detection using novel isothermal gene amplification method based on three-way junction

Jeong Moon et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Review Biochemistry & Molecular Biology

Exosomes in the tumor microenvironment as mediators of cancer therapy resistance

Irene Li et al.

MOLECULAR CANCER (2019)

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Article Chemistry, Analytical

Rapid, sensitive and highly specific label-free fluorescence biosensor for microRNA by branched rolling circle amplification

Qian Ma et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

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Article Gastroenterology & Hepatology

Interleukin 1 Up-regulates MicroRNA 135b to Promote Inflammation-Associated Gastric Carcinogenesis in Mice

Tae-Su Han et al.

GASTROENTEROLOGY (2019)

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Article Chemistry, Multidisciplinary

Highly sensitive detection of prostate cancer specific PCA3 mimic DNA using SERS-based competitive lateral flow assay

Xiuli Fu et al.

NANOSCALE (2019)

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Article Chemistry, Multidisciplinary

An Ultrasensitive Diagnostic Biochip Based on Biomimetic Periodic Nanostructure-Assisted Rolling Circle Amplification

Qian Yao et al.

ACS NANO (2018)

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Article Oncology

Cancer Statistics, 2018

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2018)

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Review Chemistry, Medicinal

Research Progress on Rolling Circle Amplification (RCA)-Based Biomedical Sensing

Lide Gu et al.

PHARMACEUTICALS (2018)

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Review Chemistry, Multidisciplinary

Exosomes: new molecular targets of diseases

Saheli Samanta et al.

ACTA PHARMACOLOGICA SINICA (2018)

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Review Oncology

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

Raffaele Palmirotta et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)

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Review Chemistry, Multidisciplinary

The Discovery of Rolling Circle Amplification and Rolling Circle Transcription

Michael G. Mohsen et al.

ACCOUNTS OF CHEMICAL RESEARCH (2016)

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Review Gastroenterology & Hepatology

Significance of microRNA 21 in gastric cancer

Durairaj Sekar et al.

CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2016)

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Review Oncology

MicroRNA biogenesis pathways in cancer

Shuibin Lin et al.

NATURE REVIEWS CANCER (2015)

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Review Cell Biology

Regulation of microRNA biogenesis

Minju Ha et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

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Article Chemistry, Analytical

High Specific and Ultrasensitive Isothermal Detection of MicroRNA by Padlock Probe-Based Exponential Rolling Circle Amplification

Haiyun Liu et al.

ANALYTICAL CHEMISTRY (2013)

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Review Cardiac & Cardiovascular Systems

Novel techniques and targets in cardiovascular microRNA research

S. Dangwal et al.

CARDIOVASCULAR RESEARCH (2012)

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Review Hematology

The role of microRNAs in normal and malignant hematopoiesis

Diamantina Vasilatou et al.

EUROPEAN JOURNAL OF HAEMATOLOGY (2010)

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Article Cell Biology

Control of cell proliferation pathways by microRNAs

Maria Jose Bueno et al.

CELL CYCLE (2008)

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Article Cell Biology

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Xi Chen et al.

CELL RESEARCH (2008)

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Article Biochemical Research Methods

Improved northern blot method for enhanced detection of small RNA

Gurman S. Pall et al.

NATURE PROTOCOLS (2008)

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Article Biochemistry & Molecular Biology

miR-21-mediated tumor growth

M.-L. Si et al.

ONCOGENE (2007)

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Isothermal amplification-mediated lateral flow biosensors for in vitro diagnosis of gastric cancer-related microRNAs

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