☆ 4.2 Article

In vitro modeling of amyotrophic lateral sclerosis with induced pluripotent stem cell technology-derived cell line ORIONi002-A

STEM CELL RESEARCH (2022)

Improving clinical trial outcomes in amyotrophic lateral sclerosis

Matthew C. Kiernan et al.

Summary: Researchers emphasize that a better understanding of the biological processes in amyotrophic lateral sclerosis has led to the identification of pathogenic targets and an increasing likelihood of effective therapies. Additionally, advancements in precision medicine and improved clinical trial designs will facilitate the acceleration of therapeutic approaches.

NATURE REVIEWS NEUROLOGY (2021)

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Review Neurosciences