期刊
SENSORS
卷 22, 期 12, 页码 -出版社
MDPI
DOI: 10.3390/s22124384
关键词
accelerometer; gyroscope; seismocardiography; telemonitoring; acute myocardial infarction; STEMI; electrocardiography; ECG
资金
- Finnish Foundation for Cardiovascular Research, Helsinki, Finland
- Clinical Research Fund (EVO) of Turku University Hospital, Turku, Finland
- Business Finland [1788/31/2019]
This study investigates changes in mechanocardiographic (MCG) signals in patients with ST elevation myocardial infarction (STEMI) and finds that mechanical signals recorded on the chest with accelerometers and gyroscopes can be used to differentiate STEMI patients from stable patients. This study provides a novel approach for early screening of STEMI.
Novel means to minimize treatment delays in patients with ST elevation myocardial infarction (STEMI) are needed. Using an accelerometer and gyroscope on the chest yield mechanocardiographic (MCG) data. We investigated whether STEMI causes changes in MCG signals which could help to detect STEMI. The study group consisted of 41 STEMI patients and 49 control patients referred for elective coronary angiography and having normal left ventricular function and no valvular heart disease or arrhythmia. MCG signals were recorded on the upper sternum in supine position upon arrival to the catheterization laboratory. In this study, we used a dedicated wearable sensor equipped with 3-axis accelerometer, 3-axis gyroscope and 1-lead ECG in order to facilitate the detection of STEMI in a clinically meaningful way. A supervised machine learning approach was used. Stability of beat morphology, signal strength, maximum amplitude and its timing were calculated in six axes from each window with varying band-pass filters in 2-90 Hz range. In total, 613 features were investigated. Using logistic regression classifier and leave-one-person-out cross validation we obtained a sensitivity of 73.9%, specificity of 85.7% and AUC of 0.857 (SD = 0.005) using 150 best features. As a result, mechanical signals recorded on the upper chest wall with the accelerometers and gyroscopes differ significantly between STEMI patients and stable patients with normal left ventricular function. Future research will show whether MCG can be used for the early screening of STEMI.
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