期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 828, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2022.154432
关键词
Metconazole; Stcreoselectivity; Aquatic toxicity; Fusarium verticillioides; Fungicidal activity; Fumonisin B-1
资金
- National Natural Science Foundation of China [31871987]
This study systematically assessed the stereochemical isomers of chiral triazole fungicide metconazole, revealing enantioselective toxicity towards aquatic organisms and effects on the pathogen Fusarium verricillioides. Among the four stereoisomers, (1S,5R)-metconazole exhibited the highest fungicidal activity.
The chiral triazole fungicide metconazole has four stereoisomers, is a broad-spectrum fungicide and is widely used for controlling Fusarium head blight caused by Fusarium species. In this study, systemic assessments of metconazole stereoisomers were performed, including stereoselective toxicity toward the aquatic organism Daphnia magna, fungicidal activity and effects on fumonisin production by the pathogen Fusarium verricillioides (F. verticillinides) in relation to different conditions. The toxicity of metconazole was enantioselective, and there was a 2.1-2.9-fold difference. The activities of superoxide dismutase (SOD) and catalase (CAT) increased and decreased, respectively, after treatment with metconazole stereoisomers, and the differences were observed among the stereoisomers. Among the four stereoisomers, (1S,5R)-metconazole showed the highest fungicidal activity under all assayed conditions, and the differences ranged from 4.4 to 45.2 times. Moreover, metconazole stereoisomers can stereoselectively affect on fumonisin B-1 production by F. verticillioides and abiotic factors, such as water activity and temperature, play an important role. Our study provides new insight into metconazole at the stereoisomeric level, including its toxicity, bioactivity, and effect on Mtsarium species producing mycotoxins.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据