期刊
RESPIROLOGY
卷 27, 期 10, 页码 863-873出版社
WILEY
DOI: 10.1111/resp.14321
关键词
airborne particle; bronchoscopy; coronavirus disease; COVID-19; e-mask; prevention; respiratory protective devices
资金
- FOREST/CREST (JST)
- KAKEN (JSPS) [18K15923, 21K07217]
- Yahoo Japan kikin
- Nagoya University
This study evaluated the use of an e-mask during bronchoscopy and found that it significantly reduced the generation of airborne particles, while not increasing the risk of respiratory complications.
Background and objective Bronchoscopy is an airborne particle-generating procedure. However, few methods for safe bronchoscopy have been developed. To reduce airborne particles during bronchoscopy, we created an 'e-mask', which is a simple, disposable mask for patients. Our objective was to evaluate the e-mask's protective ability against airborne particles and to assess respiratory adverse events and complications. Methods Patients with stage 2-4 chronic obstructive pulmonary disease were excluded. We performed visualization and quantifying experiments on airborne particles with and without the e-mask. We prospectively evaluated whether wearing the e-mask during bronchoscopy was associated with the incidence of patients requiring >5 L/min oxygen to maintain >90% oxygen saturation, and patients with >45 mm Hg end-tidal carbon dioxide (EtCO2) elevation, in addition to complications, compared to historical controls. Results In the visualization experiment, more than ten thousand times of airborne particles were generated without the e-mask than with the e-mask. The volume of airborne particles was significantly reduced with the e-mask, compared to that without the e-mask (p = 0.011). Multivariate logistic regression analysis revealed that wearing the e-mask had no significant effect on the incidence of patients requiring >5 L/min oxygen to maintain >90% oxygen saturation, (p = 0.959); however, wearing the e-mask was a significant factor in >45 mm Hg EtCO2 elevation (p = 0.026). No significant differences in complications were observed between the e-mask and control groups (5.8% vs. 2.5%, p = 0.395). Conclusion Wearing the e-mask during bronchoscopy significantly reduced the generation of airborne particles during bronchoscopy without increasing complications.
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