Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer

Background Chemotherapeutic drugs are principally intended to treat breast cancer. However, sooner or later, tumor drug resistance developed. These chemo drugs are effective but with numerous side effects. Breast cancer care may be extremely difficult since recurring cancer is frequently pre-treated with powerful agents. Cancer cells acquire high resistance to earlier therapies, necessitating alternative and more powerful drugs. Nanoparticles (NPs) as a medication delivery technology can overcome medication resistance in breast cancer and significantly reduce the effective dose. The off-targeted nature of chemo drugs can be resolved by encapsulating or attaching chemo drugs in nanocarriers, specifically targeting breast cancer cells. Objectives This review highlights various chemo drugs for breast cancer and their encapsulation or bioconjugation with nanoparticles for its targeted delivery. Conclusion Nanoparticles may subsist valuable abet in breast cancer management in this regard. Given that traditional chemotherapy approaches have been demonstrated to have several side effects and defects during treatment, the NPs-mediated drug delivery mechanism is a possible contender for replacement as a new technique.

Automated summary

Chemotherapeutic drugs for breast cancer face challenges of drug resistance and side effects. Nanoparticles as medication delivery technology can overcome resistance and reduce effective dose. Encapsulating or attaching chemo drugs in nanocarriers specifically targeting breast cancer cells can solve the off-targeted nature of chemo drugs.