Comparing radiolytic production of H2O2 and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams

The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at >= 1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.(c) 2022 The Authors. Published by Elsevier B.V. Radiotherapy and Oncology 175 (2022) 197-202 This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Automated summary

The study investigated the physico-chemical and biological responses to conventional and UHDR electron and proton beams, including conventional photons. The temporal structure and nature of the beams had an impact on both, with electron beams at >= 1400 Gy/s and proton beams at 0.1 and 1260 Gy/s found to have an isoefficient effect on sparing zebrafish embryos.