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Article
Radiology, Nuclear Medicine & Medical Imaging
M. T. Tsakok et al.
Summary: This study aimed to compare the radiological, biochemical, and clinical severity between patients infected with Alpha-variant SARS-CoV-2 and those infected with pre-existing strains, as well as to determine whether the computed tomography (CT) severity score (CTSS) for COVID-19 pneumonitis is correlated with clinical severity and can predict outcomes.
CLINICAL RADIOLOGY
(2022)
Article
Medicine, General & Internal
Nicole Wolter et al.
Summary: According to data analysis from South Africa, individuals infected with the omicron variant have a lower likelihood of hospitalization compared to those infected with non-omicron variants. Furthermore, individuals infected with the omicron variant have a lower odds of severe disease compared to individuals infected with the earlier delta variant.
Article
Multidisciplinary Sciences
Kenrie P. Y. Hui et al.
Summary: SARS-CoV-2 variants pose a threat to global public health. The Omicron variant replicates faster in bronchi but less efficiently in the lung parenchyma compared to other variants. All variants of concern have similar cellular tropism.
Article
Multidisciplinary Sciences
Yunlong Cao et al.
Summary: The Omicron variant of SARS-CoV-2 contains 15 mutations in the receptor-binding domain, leading to evasion of over 85% of tested neutralizing antibodies. Different epitope groups of neutralizing antibodies are affected to varying degrees by single mutations of Omicron. Antibodies targeting the conserved region of sarbecovirus remain most effective against Omicron.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jong Eun Lee et al.
Summary: This study evaluated the clinical and imaging characteristics of patients with COVID-19 breakthrough infections and found that compared with unvaccinated patients, breakthrough infection patients had a lower proportion of pneumonia on chest CT scans, as well as a lower risk of requiring supplemental oxygen and intensive care unit admission. This suggests that vaccines still play an important role in preventing severe illness and hospitalization.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Mark Schiebler et al.
Article
Medicine, Research & Experimental
Flavia Biamonte et al.
Summary: Through a retrospective evaluation of laboratory parameters in 45 elderly subjects, three laboratory response patterns were identified, strongly associated with patients' survival. Key markers such as D-dimer, iron status, and lymphocyte/monocyte count were found to play significant roles in predicting clinical progression in COVID-19 patients.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Immunology
Igor Kos et al.
Summary: The study compared the immune status of COVID-19 patients and found significant cellular immune abnormalities in severe patients, with the reduced B/T8-cell ratio and decreased rate of activated monocytes being important indicators related to death.
EUROPEAN JOURNAL OF IMMUNOLOGY
(2021)
Article
Critical Care Medicine
Hugo J. A. Adams et al.
Article
Infectious Diseases
J. C. Marshall et al.
LANCET INFECTIOUS DISEASES
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas C. Kwee et al.