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Paul B. Lawrence et al.
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A. Mero et al.
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Gianfranco Pasut et al.
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Anathe O. M. Patschull et al.
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Yuko Tsutsui et al.
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Joshua L. Price et al.
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Bitten Plesner et al.
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Karen Chiu et al.
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Yi-Pin Chang et al.
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Meera Mallyat et al.
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Oktay K. Gasymov et al.
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Daniel Kolarich et al.
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PTG Elkington et al.
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FM Veronese et al.
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B Korkmaz et al.
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S Frokjaer et al.
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J Dobó et al.
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UB Kang et al.
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AM Cantin et al.
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H García-Arellano et al.
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Detection of circulating and endothelial cell polymers of Z and wild type α1-antitrypsin by a monoclonal antibody
S Janciauskiene et al.
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DJ Tew et al.
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ST Tran et al.
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