4.5 Review

Recent advances in animal models of systemic sclerosis

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Meeting Abstract Rheumatology

SYSTEMIC SCLEROSIS-LIKE HISTOPATHOLOGICAL FEATURES IN THE MYOCARDIUM OF UPAR-DEFICIENT MICE

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ANNALS OF THE RHEUMATIC DISEASES (2015)

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Emerging Roles of Innate Immune Signaling and Toll-Like Receptors in Fibrosis and Systemic Sclerosis

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CURRENT RHEUMATOLOGY REPORTS (2015)

Article Rheumatology

Cardiomyopathy in Murine Models of Systemic Sclerosis

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ARTHRITIS & RHEUMATOLOGY (2015)

Article Dermatology

Fli1 deficiency contributes to the suppression of endothelial CXCL5 expression in systemic sclerosis

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ARCHIVES OF DERMATOLOGICAL RESEARCH (2014)

Review Rheumatology

The role of genetics and epigenetics in the pathogenesis of systemic sclerosis

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NATURE REVIEWS RHEUMATOLOGY (2014)

Article Cell Biology

FibronectinEDA Promotes Chronic Cutaneous Fibrosis Through Toll-like Receptor Signaling

Swati Bhattacharyya et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Multidisciplinary Sciences

Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis

Shinji Noda et al.

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Article Cell Biology

Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma

Yongqing Wang et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2013)

Article Rheumatology

Animal Models of Scleroderma: Current State and Recent Development

Yoshihide Asano et al.

CURRENT RHEUMATOLOGY REPORTS (2013)

Article Rheumatology

Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis

Britta Maurer et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

Article Rheumatology

Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis

Korsa Khan et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

Article Rheumatology

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

Christian Beyer et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

Article Rheumatology

Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis

Lukasz Stawski et al.

ARTHRITIS RESEARCH & THERAPY (2012)

Article Rheumatology

Altered dynamics of transforming growth factor β (TGF-β) receptors in scleroderma fibroblasts

Yoshihide Asano et al.

ANNALS OF THE RHEUMATIC DISEASES (2011)

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Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice

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JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Pathology

Endothelial Fli1 Deficiency Impairs Vascular Homeostasis A Role in Scleroderma Vasculopathy

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AMERICAN JOURNAL OF PATHOLOGY (2010)

Review Rheumatology

Animal Models of Systemic Sclerosis Prospects and Limitations

Christian Beyer et al.

ARTHRITIS AND RHEUMATISM (2010)

Article Medicine, Research & Experimental

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload

Norifumi Takeda et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Review Dermatology

Animal model of systemic sclerosis

Toshiyuki Yamamoto

JOURNAL OF DERMATOLOGY (2010)

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Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

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CELLULAR AND MOLECULAR LIFE SCIENCES (2009)

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Significant improvement of right ventricular function by imatinib mesylate in scleroderma-associated pulmonary arterial hypertension

Henrik ten Freyhaus et al.

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Article Immunology

Selective Oxidation of DNA Topoisomerase 1 Induces Systemic Sclerosis in the Mouse

Amelie Servettaz et al.

JOURNAL OF IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

Transcription Factor Fli1 Regulates Collagen Fibrillogenesis in Mouse Skin

Yoshihide Asano et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Rheumatology

Transforming growth factor β as a therapeutic target in systemic sclerosis

John Varga et al.

NATURE REVIEWS RHEUMATOLOGY (2009)

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The Absence of uPAR Is Associated with the Progression of Dermal Fibrosis

Yosuke Kanno et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)

Article Multidisciplinary Sciences

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1

Robert Eferl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell Biology

Urokinase receptor cleavage: A crucial step in 14 fibroblast-to-myofibroblast differentiation

Audrey M. Bernstein et al.

MOLECULAR BIOLOGY OF THE CELL (2007)

Letter Rheumatology

B cell infiltration in systemic sclerosis-associated interstitial lung disease

Robert Lafyatis et al.

ARTHRITIS AND RHEUMATISM (2007)

Review Rheumatology

B lymphocytes and systemic sclerosis

M Fujimoto et al.

CURRENT OPINION IN RHEUMATOLOGY (2005)

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Circulating fibrocytes: collagen-secreting cells of the peripheral blood

TE Quan et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Pathology

Increased expression levels of integrin αvβ5 on scleroderma fibroblasts

Y Asano et al.

AMERICAN JOURNAL OF PATHOLOGY (2004)

Article Biochemistry & Molecular Biology

Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors

PC Hollenhorst et al.

NUCLEIC ACIDS RESEARCH (2004)

Article Multidisciplinary Sciences

Systemic and cell type-specific gene expression patterns in scleroderma skin

ML Whitfield et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Cell Biology

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

GM Di Guglielmo et al.

NATURE CELL BIOLOGY (2003)

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uPAR: A versatile signalling orchestrator

F Blasi et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Multidisciplinary Sciences

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

YY Zhao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Multidisciplinary Sciences

Deficient Smad7 expression: A putative molecular defect in scleroderma

CM Dong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway

J Czuwara-Ladykowska et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

DD Spyropoulos et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)