☆ 4.6 Article

Natural history of pituitary apoplexy: a long-term follow-up study

POSTGRADUATE MEDICAL JOURNAL (2023)

GnRH agonist-associated pituitary apoplexy: a case series and review of the literature

Francisco J. Guarda et al.

Summary: This study examined the clinical presentation and longitudinal outcome of Pituitary Apoplexy (PA) after gonadotropin-releasing hormone agonist (GnRHa) in seven patients. Results showed that patients typically presented symptoms within 24 hours of initial dose, with common manifestations including headache, nausea, and vomiting. Pathologic specimens from surgically treated patients mostly stained positive for gonadotropins.

PITUITARY (2021)

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Review Clinical Neurology

Coronavirus Disease 2019 and Pituitary Apoplexy: A Single-Center Case Series and Review of the Literature

Rafael Martinez-Perez et al.

Summary: This study identified 3 cases of pituitary apoplexy with concomitant COVID-19 infection, with symptoms including headache and vision changes. The patients were successfully treated with surgery and medical management, showing improvement in visual symptoms. The study suggests that COVID-19 infection may be a risk factor for the development of pituitary apoplexy, but further research is needed.

WORLD NEUROSURGERY (2021)

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Review Clinical Neurology