Removal of clinically relevant SARS-CoV-2 variants by an affinity resin containing Galanthus nivalis agglutinin

Letter Immunology

Increased immune escape of the new SARS-CoV-2 variant of concern Omicron

Jie Hu et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2022)

Article Immunology

Association Between SARS-CoV-2 RNAemia and Postacute Sequelae of COVID-19

Nikhil Ram-Mohan et al.

Summary: Determinants of Post-Acute Sequelae of COVID-19 are not known. This study found that the presence of viral RNA in blood (RNAemia) at presentation successfully predicted the occurrence of post-acute symptoms, independent of patient demographics, disease severity, and length of symptoms.

OPEN FORUM INFECTIOUS DISEASES (2022)

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Letter Medicine, General & Internal

Efficacy of Antiviral Agents against the SARS-CoV-2 Omicron Subvariant BA.2

Emi Takashita et al.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Immunology

Relationship Between Serum Severe Acute Respiratory Syndrome Coronavirus 2 Nucleic Acid and Organ Damage in Coronavirus 2019 Patients: A Cohort Study

Dan Xu et al.

Summary: The study revealed that serum SARS-CoV-2 RNA was frequently detected in COVID-19 patients between 11 and 15 days after symptom onset. Patients with RNAemia often exhibited organ damage, abnormal laboratory biomarkers, and higher mortality rates.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Medicine, General & Internal

Removal of COVID-19 Spike Protein, Whole Virus, Exosomes, and Exosomal MicroRNAs by the Hemopurifier® Lectin-Affinity Cartridge in Critically Ill Patients With COVID-19 Infection

Dennis E. Amundson et al.

Summary: Viremia is associated with severe complications and poor outcomes in COVID-19 infections, while exosomes are believed to be involved in the pathogenesis. Hemopurifier may help improve patients' conditions by removing viruses and exosomes, with positive results seen in two critically ill patients.

FRONTIERS IN MEDICINE (2021)

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Review Microbiology

SARS-CoV-2 variants, spike mutations and immune escape

William T. Harvey et al.

Summary: The evolution of SARS-CoV-2 has been characterized by the emergence of mutations and variants that impact virus characteristics. Manufacturers are preparing for possible updates to vaccines in response to changes in the virus population, and it is crucial to monitor genetic and antigenic changes alongside experiments to understand the impacts of mutations.

NATURE REVIEWS MICROBIOLOGY (2021)

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Article Hematology