Risk factors associated with tuberculosis recurrence in South Korea determined using a nationwide cohort study

Article Immunology

High Rates of Recurrent Tuberculosis Disease: A Population-level Cohort Study

Sabine M. Hermans et al.

Summary: The study found that the rate of recurrent tuberculosis increases with subsequent episodes, regardless of HIV status. HIV infection alone may not explain the high burden of recurrence, suggesting a combination of high infection risk and increased risk associated with previous tuberculosis episodes. High recurrence rates indicate a need for increased tuberculosis surveillance in patients with more than one episode.

CLINICAL INFECTIOUS DISEASES (2021)

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Review Respiratory System

Recurrent TB: a systematic review and meta-analysis of the incidence rates and the proportions of relapses and reinfections

Victor Vega et al.

Summary: The study demonstrates that recurrent tuberculosis has a high incidence rate, with relapse accounting for 70% and reinfection for 30%. Genotyping is an important tool for distinguishing between relapse and reinfection. The incidence rate of recurrent tuberculosis is influenced by various factors such as HIV prevalence, treatment drug regimen, etc.

THORAX (2021)

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Article Infectious Diseases

Tuberculosis recurrence over a 7-year follow-up period in successfully treated patients in a routine program setting in China: a prospective longitudinal study

Yan Lin et al.

Summary: The study conducted in Jiangxi Province, China, found a significantly higher recurrence rate among previously successfully treated TB patients, especially in the age range of 34-73 years and among current smokers.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Review Respiratory System