期刊
PITUITARY
卷 25, 期 5, 页码 693-697出版社
SPRINGER
DOI: 10.1007/s11102-022-01249-5
关键词
Cortisol; Adrenal; Pituitary; Cushing's disease; UFC; DST
Diagnosis of Cushing's syndrome is often delayed due to its rarity and variable clinical features. Simple and accurate screening tests, such as overnight dexamethasone suppression test and urinary free cortisol test, are necessary to enhance screening for hypercortisolism.
Diagnosis of Cushing's syndrome (CS) is often delayed due to variable clinical features and its rarity. Simple and accurate screening tests are required to enhance screening for hypercortisolism. Both overnight 1 mg dexamethasone suppression test (DST) and urinary free cortisol (UFC) demonstrate high sensitivity and specificity for the diagnosis of CS. However, each test has its own distinctive features, making it preferable in specific clinical conditions. This review will discuss the pitfalls for each of those tests.
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