相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature
Chakrabhavi Dhananjaya Mohan et al.
SEMINARS IN CANCER BIOLOGY (2022)
Repurposing of drugs as STAT3 inhibitors for cancer therapy
Pathum S. Thilakasiri et al.
SEMINARS IN CANCER BIOLOGY (2021)
mir-21-5p inhibits the progression of human chondrosarcoma by regulating CCR7/STAT3/NF-κB pathway
Guosong Li et al.
CONNECTIVE TISSUE RESEARCH (2021)
Paeonol inhibits proliferation and induces cell apoptosis of human T24 and 5637 bladder cancer cells in vitro and in vivo
J. J. Zhang et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2021)
LINC00941promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway
Nan Wu et al.
CELL DEATH AND DIFFERENTIATION (2021)
Quercetin suppresses pancreatic ductal adenocarcinoma progression via inhibition of SHH and TGF-β/Smad signaling pathways
Yangyang Guo et al.
CELL BIOLOGY AND TOXICOLOGY (2021)
C-Myc Signaling Pathway in Treatment and Prevention of Brain Tumors
Milad Ashrafizadeh et al.
CURRENT CANCER DRUG TARGETS (2021)
Recent advances and future directions in anti-tumor activity of cryptotanshinone: A mechanistic review
Milad Ashrafizadeh et al.
PHYTOTHERAPY RESEARCH (2021)
Temozolomide treatment outcomes and immunotherapy efficacy in brain tumor
Kelly M. Hotchkiss et al.
JOURNAL OF NEURO-ONCOLOGY (2021)
EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1-2 signaling
Yutian Wei et al.
NEURO-ONCOLOGY (2021)
TGF-β1 modulates temozolomide resistance in glioblastoma via altered microRNA processing and elevated MGMT
Er Nie et al.
NEURO-ONCOLOGY (2021)
Modeling betterin vitromodels for the prediction of nanoparticle toxicity: a review
Yi Cao et al.
TOXICOLOGY MECHANISMS AND METHODS (2021)
Recombinant Human IL-11 Promotes Lung Adenocarcinoma A549 Cell Growth and EMT through Activating STAT3/HIF-1α/EMT Signaling Pathway
Na Peng et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2021)
Targeting Hypoxia-Inducible Factor-1-Mediated Metastasis for Cancer Therapy
Zhaowu Ma et al.
ANTIOXIDANTS & REDOX SIGNALING (2021)
BTF3 promotes sternness and inhibits Typellnterferon signaling pathway in triple-negative breast cancer
Hexiang Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Designing precision medicine panels for drug refractory cancers targeting cancer stemness traits
Sudha Warrier et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Cisplatin loaded multiwalled carbon nanotubes reverse drug resistance in NSCLC by inhibiting EMT
Yuxin Qi et al.
CANCER CELL INTERNATIONAL (2021)
A Positive Feedback Loop of AKR1C3-Mediated Activation of NF-κB and STAT3 Facilitates Proliferation and Metastasis in Hepatocellular Carcinoma
Qingqing Zhou et al.
CANCER RESEARCH (2021)
Role of STAT3 signaling transduction pathways in cancer stem cell-associated chemoresistance
Po-Chang Shih et al.
DRUG DISCOVERY TODAY (2021)
The Multifaced Role of STAT3 in Cancer and Its Implication for Anticancer Therapy
Manlio Tolomeo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Dual relationship between long non-coding RNAs and STAT3 signaling in different cancers: New insight to proliferation and metastasis
Milad Ashrafizadeh et al.
LIFE SCIENCES (2021)
LGR5 induces β-catenin activation and augments tumour progression by activating STAT3 in human intrahepatic cholangiocarcinoma
Keishi Kawasaki et al.
LIVER INTERNATIONAL (2021)
The Microfluidic Toolbox for Analyzing Exosome Biomarkers of Aging
Jonalyn DeCastro et al.
MOLECULES (2021)
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway
Alexander Swoboda et al.
ONCOGENE (2021)
BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C
Yuan Zhang et al.
CELL DEATH & DISEASE (2021)
Interplay between p53 and non-coding RNAs in the regulation of EMT in breast cancer
Sergey Parfenyev et al.
CELL DEATH & DISEASE (2021)
PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas
Changhwan Yoon et al.
ONCOGENESIS (2021)
Small hepatitis B virus surface antigen promotes malignant progression of hepatocellular carcinoma via endoplasmic reticulum stress-induced FGF19/JAK2/STAT3 signaling
Shuxiang Wu et al.
CANCER LETTERS (2021)
HPRT promotes proliferation and metastasis in head and neck squamous cell carcinoma through direct interaction with STAT3
Lin Wang et al.
EXPERIMENTAL CELL RESEARCH (2021)
The role of SOX family transcription factors in gastric cancer
Asal Jalal Abadi et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)
Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis
Ming-Yue Li et al.
MOLECULAR CANCER (2021)
Cucurbitacin I (JSI-124)-dependent inhibition of STAT3 permanently suppresses the pro-carcinogenic effects of active breast cancer-associated fibroblasts
Bothaina Al-Harbi et al.
MOLECULAR CARCINOGENESIS (2021)
Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3
Sabrina Tripolt et al.
NEOPLASIA (2021)
Exosomal miR-128-3p Promotes Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF-β/SMAD and JAK/STAT3 Signaling
Jian Bai et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
EPHB2 Activates β-Catenin to Enhance Cancer Stem Cell Properties and Drive Sorafenib Resistance in Hepatocellular Carcinoma
Hoi-Wing Leung et al.
CANCER RESEARCH (2021)
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway
YuJian Xia et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2021)
Combination of Niraparib, Cisplatin and Twist Knockdown in Cisplatin-Resistant Ovarian Cancer Cells Potentially Enhances Synthetic Lethality through ER-Stress Mediated Mitochondrial Apoptosis Pathway
Entaz Bahar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Nitidine chloride suppresses epithelial-mesenchymal transition and stem cell-like properties in glioblastoma by regulating JAK2/STAT3 signaling
Mingbo Jia et al.
CANCER MEDICINE (2021)
Quercetin and Its Nano-Scale Delivery Systems in Prostate Cancer Therapy: Paving the Way for Cancer Elimination and Reversing Chemoresistance
Yaseen Hussain et al.
CANCERS (2021)
Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis
Arpita Datta et al.
CANCERS (2021)
Silencing of ITGB6 inhibits the progression of cervical carcinoma via regulating JAK/STAT3 signaling pathway
Xiaoxia Zheng et al.
ANNALS OF TRANSLATIONAL MEDICINE (2021)
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation
Yangyang Guo et al.
Aging-US (2021)
Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma
Chakrabhavi Dhananjaya Mohan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Aspirin facilitates trophoblast invasion and epithelial-mesenchymal transition by regulating the miR-200-ZEB1 axis in preeclampsia
Mei-Tsz Su et al.
BIOMEDICINE & PHARMACOTHERAPY (2021)
New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities
Milad Ashrafizadeh et al.
BIOMEDICINE & PHARMACOTHERAPY (2021)
Long non-coding RNAs in the doxorubicin resistance of cancer cells
Saeed Ashrafizaveh et al.
CANCER LETTERS (2021)
Regulation of Nuclear Factor-KappaB (NF-kB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?
Sepideh Mirzaei et al.
CANCER LETTERS (2021)
ETV4 transcriptionally activates HES1 and promotes Stat3 phosphorylation to promote malignant behaviors of colon adenocarcinoma
Dan Yao et al.
CELL BIOLOGY INTERNATIONAL (2021)
Interplay between SOX9 transcription factor and microRNAs in cancer
Milad Ashrafizadeh et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)
Therapeutic potential of AMPK signaling targeting in lung cancer: Advances, challenges and future prospects
Milad Ashrafizadeh et al.
LIFE SCIENCES (2021)
Curcumin inhibits the viability, migration and invasion of papillary thyroid cancer cells by regulating the miR-301a-3p/STAT3 axis
Ying Liang et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2021)
MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway
Qiutong Li et al.
FEBS OPEN BIO (2021)
The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment
Muyue Yang et al.
BIOACTIVE MATERIALS (2021)
Exosome in Hepatocellular Carcinoma: an update
Wei Chen et al.
JOURNAL OF CANCER (2021)
Linking EMT programmes to normal and neoplastic epithelial stem cells
Arthur W. Lambert et al.
NATURE REVIEWS CANCER (2021)
Combination of Huanglian Jiedu Decoction and erlotinib delays growth and improves sensitivity of EGFR-mutated NSCLC cells in vitro and in vivo via STAT3/Bcl-2 signaling
Xiaowen Zhou et al.
ONCOLOGY REPORTS (2021)
Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis
Tong Sun et al.
ACTA PHARMACOLOGICA SINICA (2021)
SATB1 Knockdown Inhibits Proliferation and Invasion and Decreases Chemoradiation Resistance in Nasopharyngeal Carcinoma Cells by Reversing EMT and Suppressing MMP-9
Dongni Zhou et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2021)
Downregulation of N-myc Interactor Promotes Cervical Cancer Cells Growth by Activating Stat3 Signaling
Songbin Wu et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2021)
Molecular Mechanism ofHelicobacter pylori-Induced Gastric Cancer
Majid Alipour
JOURNAL OF GASTROINTESTINAL CANCER (2021)
Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics
Yixin Wang et al.
JOURNAL OF CANCER (2021)
STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
Christina Heichler et al.
GUT (2020)
The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell
Mustafa Hoca et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2020)
IL6/STAT3 Signaling Orchestrates Premetastatic Niche Formation and Immunosuppressive Traits in Lung
Bo Jing et al.
CANCER RESEARCH (2020)
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway
Yadong Liu et al.
LIFE SCIENCES (2020)
Pracinostat (SB939), a histone deacetylase inhibitor, suppresses breast cancer metastasis and growth by inactivating the IL-6/STAT3 signalling pathways
Jing Chen et al.
LIFE SCIENCES (2020)
Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review
Mahshid Moballegh Nasery et al.
MOLECULES (2020)
Quercetin Inhibits Cell Survival and Metastatic Ability via the EMT-Mediated Pathway in Oral Squamous Cell Carcinoma
So Ra Kim et al.
MOLECULES (2020)
The biology, function, and biomedical applications of exosomes
Raghu Kalluri et al.
SCIENCE (2020)
Meg3 Induces EMT and Invasion of Glioma Cells via Autophagy
Zhihao Yang et al.
ONCOTARGETS AND THERAPY (2020)
Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial-Mesenchymal Transition
Wook Jin
CELLS (2020)
Downregulation of Rab17 promotes cell proliferation and invasion in non-small cell lung cancer through STAT3/HIF-1α/VEGF signaling
Mingliang Wang et al.
THORACIC CANCER (2020)
A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction
Soo Kyung Park et al.
BIOCHEMICAL PHARMACOLOGY (2020)
TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation
Yasuhiro Yoshimatsu et al.
CANCER SCIENCE (2020)
Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis
Alexander Charles Ford et al.
GUT (2020)
Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition
Chien-Shan Cheng et al.
CANCER MANAGEMENT AND RESEARCH (2020)
B7-H3 Regulates Glioma Growth and Cell Invasion Through a JAK2/STAT3/Slug-Dependent Signaling Pathway
Chuanhong Zhong et al.
ONCOTARGETS AND THERAPY (2020)
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling
Renlun Huang et al.
CELL DEATH & DISEASE (2020)
CAPN1 promotes malignant behavior and erlotinib resistance mediated by phosphorylation of c-Met and PIK3R2 via degrading PTPN1 in lung adenocarcinoma
Yichuan Chen et al.
THORACIC CANCER (2020)
Oxaliplatin-Induced DHX9 Phosphorylation Promotes Oncogenic Circular RNA CCDC66 Expression and Development of Chemoresistance
Ya-Chi Lin et al.
CANCERS (2020)
Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells
Changying Shi et al.
AGING-US (2020)
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma
Ye Lin et al.
AGING-US (2020)
Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial
Shuhong Wang et al.
CLINICAL CANCER RESEARCH (2020)
STEAP1 facilitates metastasis and epithelial-mesenchymal transition of lung adenocarcinoma via the JAK2/STAT3 signaling pathway
Shu-fen Huo et al.
BIOSCIENCE REPORTS (2020)
Piperine inhibits colorectal cancer migration and invasion by regulating STAT3/Snail-mediated epithelial-mesenchymal transition
Lingyu Song et al.
BIOTECHNOLOGY LETTERS (2020)
Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol
Jin Young Kim et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
Zeda Zhang et al.
CANCER CELL (2020)
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
Rasmus Siersbaek et al.
CANCER CELL (2020)
Hypoxia-induced lncRNA RP11-390F4.3 promotes epithelial-mesenchymal transition (EMT) and metastasis through upregulating EMT regulators
Pei-Hua Peng et al.
CANCER LETTERS (2020)
MicroRNA 345 (miR345) regulates KISS1-E-cadherin functional interaction in breast cancer brain metastases
Ilya Ulasov et al.
CANCER LETTERS (2020)
Hypoxia-inhibited miR-338-3p suppresses breast cancer progression by directly targeting ZEB2
Juanjuan He et al.
CANCER SCIENCE (2020)
ITGBL1 promotes cell migration and invasion through stimulating the TGF-β signalling pathway in hepatocellular carcinoma
Wei Huang et al.
CELL PROLIFERATION (2020)
Exosomal Transfer of LCP1 Promotes Osteosarcoma Cell Tumorigenesis and Metastasis by Activating the JAK2/STAT3 Signaling Pathway
Xuhui Ge et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2020)
AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1
Manar M. AlAhmari et al.
ONCOGENESIS (2020)
Association of the Epithelial-Mesenchymal Transition (EMT) with Cisplatin Resistance
Milad Ashrafizadeh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
EMT-Associated Heterogeneity in Circulating Tumor Cells: Sticky Friends on the Road to Metastasis
Anthony Genna et al.
CANCERS (2020)
Impact of Metformin Use on Survival in Patients with Gastric Cancer and Diabetes Mellitus Following Gastrectomy
Wai-Shan Chung et al.
CANCERS (2020)
Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma
Jong Hyun Lee et al.
JOURNAL OF ADVANCED RESEARCH (2020)
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition
Pengzhen Dong et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Versatile role of curcumin and its derivatives in lung cancer therapy
Milad Ashrafizadeh et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2020)
MicroRNAs and Their Influence on the ZEB Family: Mechanistic Aspects and Therapeutic Applications in Cancer Therapy
Milad Ashrafizadeh et al.
BIOMOLECULES (2020)
Phytochemical Targeting of STAT3 Orchestrated Lipid Metabolism in Therapy-Resistant Cancers
Carmen Tse et al.
BIOMOLECULES (2020)
Resveratrol Modulates Transforming Growth Factor-Beta (TGF-β) Signaling Pathway for Disease Therapy: A New Insight into Its Pharmacological Activities
Milad Ashrafizadeh et al.
BIOMEDICINES (2020)
PhospholipaseD1inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity
Dong Woo Kang et al.
JOURNAL OF PATHOLOGY (2020)
CircRNA hsa_circRNA_0001776 inhibits proliferation and promotes apoptosis in endometrial cancer via downregulating LRIG2 by sponging miR-182
Youjuan Jia et al.
CANCER CELL INTERNATIONAL (2020)
Functionalized exosome harboring bioactive molecules for cancer therapy
Yoon Kyoung Kim et al.
CANCER LETTERS (2020)
Enhancer Reprogramming within Pre-existing Topologically Associated Domains Promotes TGF-β-Induced EMT and Cancer Metastasis
Yunbo Qiao et al.
MOLECULAR THERAPY (2020)
Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL-6/STAT3 signaling pathway
Tao Pan et al.
ONCOLOGY REPORTS (2020)
miR-124 regulates liver cancer stem cells expansion and sorafenib resistance
Yun Feng et al.
EXPERIMENTAL CELL RESEARCH (2020)
Novel Nanocomplexes Targeting STAT3 Demonstrate Promising Anti-Ovarian Cancer Effects in vivo
Xiaolei Zhang et al.
ONCOTARGETS AND THERAPY (2020)
Twist-mediated PAR1 induction is required for breast cancer progression and metastasis by inhibiting Hippo pathway
Yifan Wang et al.
CELL DEATH & DISEASE (2020)
STAT3 is a key molecule in the oncogenic behavior of diffuse intrinsic pontine glioma
Jinju Park et al.
ONCOLOGY LETTERS (2020)
LncRNA PVT1 induces aggressive vasculogenic mimicry formation through activating the STAT3/Slug axis and epithelial-to-mesenchymal transition in gastric cancer
Jing Zhao et al.
CELLULAR ONCOLOGY (2020)
Pentadecanoic Acid, an Odd-Chain Fatty Acid, Suppresses the Stemness of MCF-7/SC Human Breast Cancer Stem-Like Cells through JAK2/STAT3 Signaling
Ngoc Bao To et al.
NUTRIENTS (2020)
TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer
Bit Na Kim et al.
Scientific Reports (2020)
Establishment of Acquired Cisplatin Resistance in Ovarian Cancer Cell Lines Characterized by Enriched Metastatic Properties with Increased Twist Expression
Entaz Bahar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo, alone or in combination with Olaparib
Lidong Liu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects
Milad Ashrafizadeh et al.
LIFE SCIENCES (2020)
AMPK alleviates oxidative stress-induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop
Xiaojuan Han et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2020)
CircRNA inhibits DNA damage repair by interacting with host gene
Xiaolong Xu et al.
MOLECULAR CANCER (2020)
Narasin inhibits tumor metastasis and growth of ERα-positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL-6/STAT3 signaling pathways
Jing Chen et al.
MOLECULAR MEDICINE REPORTS (2020)
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis
Daniel Doheny et al.
ONCOGENE (2020)
STAT3 transcription factor as target for anti-cancer therapy
Aliaa M. Mohassab et al.
PHARMACOLOGICAL REPORTS (2020)
Sensing the scent of death: Modulation of microRNAs by Curcumin in gastrointestinal cancers
Milad Ashrafizadeh et al.
PHARMACOLOGICAL RESEARCH (2020)
IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells
Yu Li et al.
ONCOTARGETS AND THERAPY (2020)
NR5A2 Promotes Cell Growth and Resistance to Temozolomide Through Regulating Notch Signal Pathway in Glioma
Quanxi Yang et al.
ONCOTARGETS AND THERAPY (2020)
Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer
Peixin Du et al.
CELL DEATH & DISEASE (2020)
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells
Jin-Xiao Liang et al.
ONCOLOGY LETTERS (2020)
G3BP1 controls the senescence-associated secretome and its impact on cancer progression
Amr Omer et al.
NATURE COMMUNICATIONS (2020)
Progress in Natural Compounds/siRNA Co-delivery Employing Nanovehicles for Cancer Therapy
Milad Ashrafizadeh et al.
ACS COMBINATORIAL SCIENCE (2020)
Immune suppressed tumor microenvironment by exosomes derived from gastric cancer cells via modulating immune functions
Juan Liu et al.
SCIENTIFIC REPORTS (2020)
Novel role of lncRNA CHRF in cisplatin resistance of ovarian cancer is mediated by miR-10b induced EMT and STAT3 signaling
Wen-Xi Tan et al.
SCIENTIFIC REPORTS (2020)
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT
Yang Gao et al.
BIOMED RESEARCH INTERNATIONAL (2020)
DSTYK Promotes Metastasis and Chemoresistance via EMT in Colorectal Cancer
Jinyu Zhang et al.
FRONTIERS IN PHARMACOLOGY (2020)
TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance
Zonghui Ding et al.
NEOPLASIA (2020)
Mitochondrial Respiratory Defect Enhances Hepatoma Cell Invasiveness via STAT3/NFE2L1/STX12 Axis
Young-Kyoung Lee et al.
CANCERS (2020)
Metformin Suppresses Cancer Stem Cells through AMPK Activation and Inhibition of Protein Prenylation of the Mevalonate Pathway in Colorectal Cancer
Yoojeong Seo et al.
CANCERS (2020)
Perspectives Regarding the Intersections between STAT3 and Oxidative Metabolism in Cancer
Kyung-Soo Chun et al.
CELLS (2020)
A Positive Feedback Loop of lncRNA DSCR8/miR-98-5p/STAT3/HIF-1α Plays a Role in the Progression of Ovarian Cancer
Lina Dong et al.
FRONTIERS IN ONCOLOGY (2020)
SCAP Mediated GDF15-Induced Invasion and EMT of Esophageal Cancer
Gang Dong et al.
FRONTIERS IN ONCOLOGY (2020)
Corilagin Represses Epithelial to Mesenchymal Transition Process Through Modulating Wnt/β-Catenin Signaling Cascade
Sun Tae Hwang et al.
BIOMOLECULES (2020)
LncRNA CARLo-7 facilitates proliferation, migration, invasion, and EMT of bladder cancer cells by regulating Wnt/β-catenin and JAK2/STAT3 signaling pathways
Houfeng Huang et al.
TRANSLATIONAL ANDROLOGY AND UROLOGY (2020)
Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance
Yu-Ling Tsai et al.
BIOMEDICINES (2020)
Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesis
Dhakshayini Morgan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
Progress in Understanding the IL-6/STAT3 Pathway in Colorectal Cancer
Yan Lin et al.
ONCOTARGETS AND THERAPY (2020)
MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression
Haiming Ma et al.
ONCOTARGETS AND THERAPY (2020)
Toward Regulatory Effects of Curcumin on Transforming Growth Factor-Beta Across Different Diseases: A Review
Milad Ashrafizadeh et al.
FRONTIERS IN PHARMACOLOGY (2020)
STAT3 and p53: Dual Target for Cancer Therapy
Thu-Huyen Pham et al.
BIOMEDICINES (2020)
Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling
Li Liu et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2020)
miR-424-3p Contributes to the Malignant Progression and Chemoresistance of Gastric Cancer
Yongyuan Li et al.
ONCOTARGETS AND THERAPY (2020)
Paeonol Suppresses Proliferation and Motility of Non-Small-Cell Lung Cancer Cells by Disrupting STAT3/NF-κB Signaling
Lei Zhang et al.
FRONTIERS IN PHARMACOLOGY (2020)
Polychemotherapy with Curcumin and Doxorubicin via Biological Nanoplatforms: Enhancing Antitumor Activity
Milad Ashrafizadeh et al.
PHARMACEUTICS (2020)
LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling
Qiang Wang et al.
ONCOTARGETS AND THERAPY (2020)
Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer
Jie Lian et al.
JOURNAL OF CANCER (2020)
MiR-769-5p inhibits cancer progression in oral squamous cell carcinoma by directly targeting JAK1/STAT3 pathway
Y. Zhou et al.
NEOPLASMA (2020)
ALDH3A1 acts as a prognostic biomarker and inhibits the epithelial mesenchymal transition of oral squamous cell carcinoma through IL-6/STAT3 signaling pathway
Yi Qu et al.
JOURNAL OF CANCER (2020)
LncRNA H19-Derived miR-675-3p Promotes Epithelial-Mesenchymal Transition and Stemness in Human Pancreatic Cancer Cells by targeting the STAT3 Pathway
Feng Wang et al.
JOURNAL OF CANCER (2020)
Characterization of a p53/miR-34a/CSF1R/STAT3 Feedback Loop in Colorectal Cancer
Xiaolong Shi et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2020)
MEST induces Twist-1-mediated EMT through STAT3 activation in breast cancers
Min Soo Kim et al.
CELL DEATH AND DIFFERENTIATION (2019)
The expanding roles of long non-coding RNAs in the regulation of cancer stem cells
Zhaowu Ma et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)
Scutellarin inhibits proliferation and invasion of hepatocellular carcinoma cells via down-regulation of JAK2/STAT3 pathway
Kang Liu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-1-induced EMT
Rong Ma et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
被撤回的出版物: Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway (Retracted article. See vol. 42, 2023)
Zizhuo Li et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT
Xina Zhang et al.
MOLECULAR CANCER (2019)
Overexpression of Indoleamine 2,3-Dioxygenase 1 Promotes Epithelial-Mesenchymal Transition by Activation of the IL-6/STAT3/PD-L1 Pathway in Bladder Cancer
Wentao Zhang et al.
TRANSLATIONAL ONCOLOGY (2019)
Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review
Denise Fabian et al.
CANCERS (2019)
LncRNA H19 promotes epithelial mesenchymal transition and metastasis of esophageal cancer via STAT3/EZH2 axis
Ming-Jiu Chen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)
STAT3beta, a distinct isoform from STAT3
Hui-Xiang Zhang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)
The Root Bark of Morus alba L. Suppressed the Migration of Human Non-Small-Cell Lung Cancer Cells through Inhibition of Epithelial-Mesenchymal Transition Mediated by STAT3 and Src
Tae-Rin Min et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Loss of G3BP1 suppresses proliferation, migration, and invasion of esophageal cancer cells via Wnt/β-catenin and PI3K/AKT signaling pathways
Li-Na Zhang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway
Mingjing Shen et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Brassinin Represses Invasive Potential of Lung Carcinoma Cells through Deactivation of PI3K/Akt/mTOR Signaling Cascade
Min Hee Yang et al.
MOLECULES (2019)
IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
Mengmeng Liang et al.
CELL DEATH & DISEASE (2019)
Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways
Jose Esparza-Lopez et al.
BMC CANCER (2019)
TGF--Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis
Yang Hao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
YAP promotes the malignancy of endometrial cancer cells via regulation of IL-6 and IL-11
Jing Wang et al.
MOLECULAR MEDICINE (2019)
LINC81507 act as a competing endogenous RNA of miR-199b-5p to facilitate NSCLC proliferation and metastasis via regulating the CAV1/STAT3 pathway
Wei Peng et al.
CELL DEATH & DISEASE (2019)
CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway
Qin Huang et al.
FRONTIERS IN ONCOLOGY (2019)
STAT3 Targets ERR-α to Promote Epithelial-Mesenchymal Transition, Migration, and Invasion in Triple-Negative Breast Cancer Cells
Jia-Hui Ma et al.
MOLECULAR CANCER RESEARCH (2019)
REX1 promotes EMT-induced cell metastasis by activating the JAK2/STAT3-signaling pathway by targeting SOCS1 in cervical cancer
Yu-Ting Zeng et al.
ONCOGENE (2019)
The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1-STAT3 signaling pathway
Qi Lin et al.
CELL DEATH & DISEASE (2019)
Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the JAK/STAT3 pathway
Aihong Wang et al.
BIOLOGY OPEN (2019)
Annexin10 promotes extrahepatic cholangiocarcinoma metastasis by facilitating EMT via PLA2G4A/PGE2/STAT3 pathway
Rongqi Sun et al.
EBIOMEDICINE (2019)
Nanoparticles Targeting STATs in Cancer Therapy
Milad Ashrafizadeh et al.
CELLS (2019)
Insights into Biological Role of LncRNAs in Epithelial-Mesenchymal Transition
Jun-Ting Cheng et al.
CELLS (2019)
The Regulatory Role of MicroRNAs in Breast Cancer
Hui-Yi Loh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Knockdown of TRIM66 inhibits cell proliferation, migration and invasion in colorectal cancer through JAK2/STAT3 pathway
Tao He et al.
LIFE SCIENCES (2019)
Oncogenic Activities Of UBE2S Mediated By VHL/HIF-1α/STAT3 Signal Via The Ubiquitin-Proteasome System In PDAC
Lei Wang et al.
ONCOTARGETS AND THERAPY (2019)
Niclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis
Jones Gyamfi et al.
SCIENTIFIC REPORTS (2019)
Roles of Pin1 as a Key Molecule for EMT Induction by Activation of STAT3 and NF-κB in Human Gallbladder Cancer
Shinichiro Nakada et al.
ANNALS OF SURGICAL ONCOLOGY (2019)
Role of tumor-derived exosomes in cancer metastasis
Ian Wee et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)
Dietary Flavonoids Luteolin and Quercetin Inhibit Migration and Invasion of Squamous Carcinoma through Reduction of Src/Stat3/S100A7 Signaling
Jhen-Jia Fan et al.
ANTIOXIDANTS (2019)
HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation
Tingting Wang et al.
CANCER CELL INTERNATIONAL (2019)
A DHX9-lncRNA-MDM2 interaction regulates cell invasion and angiogenesis of cervical cancer
Xiangya Ding et al.
CELL DEATH AND DIFFERENTIATION (2019)
SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression
Jinfang Zhang et al.
DEVELOPMENTAL CELL (2019)
Knockdown of PYCR1 inhibits proliferation, drug resistance and EMT in colorectal cancer cells by regulating STAT3-Mediated p38 MAPK and NF-κB signalling pathway
Kun Yan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
GRIM-19 repressed hypoxia-induced invasion and EMT of colorectal cancer by repressing autophagy through inactivation of STAT3/HIF-1 signaling axis
Juan Zhang et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
CircRNAs and cancer: Biomarkers and master regulators
Esther Arnaiz et al.
SEMINARS IN CANCER BIOLOGY (2019)
Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway
Jong Hyun Lee et al.
PHARMACOLOGICAL RESEARCH (2019)
Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma
Gurubharathi Bhuvanalakshmi et al.
CANCERS (2019)
The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells
Jong Hyun Lee et al.
BIOMOLECULES (2019)
Annexin A2 Silencing Inhibits Proliferation and Epithelial-to-mesenchymal Transition through p53-Dependent Pathway in NSCLCs
Minhua Wu et al.
JOURNAL OF CANCER (2019)
ZnAs@SiO2 nanoparticles as a potential anti-tumor drug for targeting stemness and epithelial-mesenchymal transition in hepatocellular carcinoma via SHP-1/JAK2/STAT3 signaling
Yongquan Huang et al.
THERANOSTICS (2019)
被撤回的出版物: IL-6 Promotes Cancer Stemness and Oncogenicity in U2OS and MG-63 Osteosarcoma Cells by Upregulating the OPN-STAT3 Pathway (Retracted article. See vol. 12, pg. 6948, 2021)
Chuan Zhang et al.
JOURNAL OF CANCER (2019)
Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases
Shruti Mishra et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3
Tiangong Lu et al.
THERANOSTICS (2019)
TMPRSS4 Upregulates TWIST1 Expression through STAT3 Activation to Induce Prostate Cancer Cell Migration
Zhang Jianwei et al.
PATHOLOGY & ONCOLOGY RESEARCH (2018)
Interleukin-23 promotes the migration and invasion of gastric cancer cells by inducing epithelial-to-mesenchymal transition via the STAT3 pathway
Xianhui Xu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Huaier Granule extract inhibit the proliferation and metastasis of lung cancer cells through down-regulation of MTDH, JAK2/STAT3 and MAPK signaling pathways
Yang Chen et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
α-Hederin inhibits interleukin 6-induced epithelial-to-mesenchymal transition associated with disruption of JAK2/STAT3 signaling in colon cancer cells
Dongdong Sun et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Overexpression of ALK4 inhibits cell proliferation and migration through the inactivation of JAK/STAT3 signaling pathway in glioma
Chaojun Song et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
被撤回的出版物: Abnormally expressed JunB transactivated by IL-6/STAT3 signaling promotes uveal melanoma aggressiveness via epithelial-mesenchymal transition (Retracted article. See vol. 43, pg. 1, 2023)
Chaoju Gong et al.
BIOSCIENCE REPORTS (2018)
Exosome biogenesis, bioactivities and functions as new delivery systems of natural compounds
Ammad Ahmad Farooqi et al.
BIOTECHNOLOGY ADVANCES (2018)
Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells
Sung Ho Kim et al.
BMC CANCER (2018)
Pim-3 enhances melanoma cell migration and invasion by promoting STAT3 phosphorylation
Jing Liu et al.
CANCER BIOLOGY & THERAPY (2018)
miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer
Xinliang Zhou et al.
CANCER GENE THERAPY (2018)
Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model
Chulwon Kim et al.
CANCER LETTERS (2018)
Triple negative breast cancer in Asia: An insider's view
Chao Wang et al.
CANCER TREATMENT REVIEWS (2018)
microRNA-30d mediated breast cancer invasion, migration, and EMT by targeting KLF11 and activating STAT3 pathway
Mingli Han et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
YM155 decreases radiation-induced invasion and reverses epithelial-mesenchymal transition by targeting STAT3 in glioblastoma
Xin Zhang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2018)
RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3
Kai Zhou et al.
LABORATORY INVESTIGATION (2018)
Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition
Jeong-Hyeon Ko et al.
MOLECULES (2018)
Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention
Devesh Tewari et al.
PHARMACOLOGICAL RESEARCH (2018)
M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway
Rong-Rong Yao et al.
WORLD JOURNAL OF SURGICAL ONCOLOGY (2018)
G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas
Yong Wang et al.
CELL DEATH & DISEASE (2018)
Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling
Xiaochao Zhang et al.
CELL DEATH & DISEASE (2018)
Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review
Gautam Sethi et al.
NUTRIENTS (2018)
Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine
Manendra Babu Lankadasari et al.
THERANOSTICS (2018)
TGF-β-induced STAT3 overexpression promotes human head and neck squamous cell carcinoma invasion and metastasis through malat1/miR-30a interactions
Yu Wang et al.
CANCER LETTERS (2018)
Annexin A2 overexpression associates with colorectal cancer invasiveness and TGF-β induced epithelial mesenchymal transition via Src/ANXA2/STAT3
Murilo R. Rocha et al.
SCIENTIFIC REPORTS (2018)
The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
Loukik Arora et al.
CANCERS (2018)
Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis
Muthu K. Shanmugam et al.
FRONTIERS IN PHARMACOLOGY (2018)
The STAT3/Slug Axis Enhances Radiation-Induced Tumor Invasion and Cancer Stem-like Properties in Radioresistant Glioblastoma
Jang-Chun Lin et al.
CANCERS (2018)
Evidence for the Involvement of the Master Transcription Factor NF-B in Cancer Initiation and Progression
Yu Rou Puar et al.
BIOMEDICINES (2018)
Upregulation of MEK5 by Stat3 promotes breast cancer cell invasion and metastasis
Fang Liu et al.
ONCOLOGY REPORTS (2017)
Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/STAT3 and TGF-β/SMAD3 signaling pathway
Wu-ping Wang et al.
ONCOTARGET (2017)
Icariin exerts inhibitory effects on the growth and metastasis of KYSE70 human esophageal carcinoma cells via PI3K/AKT and STAT3 pathways
Zhen-Fang Gu et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2017)
Long non-coding RNA CCAT1 promotes metastasis and poor prognosis in epithelial ovarian cancer
Yuan Cao et al.
EXPERIMENTAL CELL RESEARCH (2017)
MiR-93-5p inhibits the EMT of breast cancer cells via targeting MKL-1 and STAT3
Yuan Xiang et al.
EXPERIMENTAL CELL RESEARCH (2017)
Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells
Huihui Li et al.
GASTROENTEROLOGY (2017)
Tanshinone IIA Inhibits Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Modulation of STAT3-CCL2 Signaling
Sung-Ying Huang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
miR-345 inhibits tumor metastasis and EMT by targeting IRF1-mediated mTOR/STAT3/AKT pathway in hepatocellular carcinoma
Miao Yu et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Wanted DEAD/H or Alive: Helicases Winding Up in Cancers
Wanpei Cai et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)
Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition
Bernd Groner et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2017)
PPARγ Ligand-induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers
Luxi Chen et al.
MOLECULAR CANCER THERAPEUTICS (2017)
EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
Tsukasa Shibue et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
RANDOMIZED PHASE 3 STUDY EVALUATING THE EFFICACY AND SAFETY OF NIVOLUMAB VS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: CHECKMATE 143
D. A. Reardona et al.
NEURO-ONCOLOGY (2017)
miR520c blocks EMT progression of human breast cancer cells by repressing STAT3
Nian Wang et al.
ONCOLOGY REPORTS (2017)
Irisin reverses the IL-6 induced epithelial-mesenchymal transition in osteosarcoma cell migration and invasion through the STAT3/Snail signaling pathway
Gang Kong et al.
ONCOLOGY REPORTS (2017)
Basic Transcription Factor 3 Is Required for Proliferation and Epithelial-Mesenchymal Transition via Regulation of FOXM1 and JAK2/STAT3 Signaling in Gastric Cancer
De-Zhong Zhang et al.
ONCOLOGY RESEARCH (2017)
Quercetin inhibits epithelial-mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial-mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cells
Dinglai Yu et al.
ONCOTARGETS AND THERAPY (2017)
MicroRNA-216a inhibits the metastasis of gastric cancer cells by targeting JAK2/STAT3-mediated EMT process
Youmao Tao et al.
ONCOTARGET (2017)
Chemotherapy-mediated miR-29b expression inhibits the invasion and angiogenesis of cervical cancer
Yunyun Li et al.
ONCOTARGET (2017)
ING5 knockdown enhances migration and invasion of lung cancer cells by inducing EMT via EGFR/PI3K/Akt and IL-6/STAT3 signaling pathways
Xin-Li Liu et al.
ONCOTARGET (2017)
IL-6/STAT3/TWIST inhibition reverses ionizing radiationinduced EMT and radioresistance in esophageal squamous carcinoma
Chunbao Zang et al.
ONCOTARGET (2017)
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway
Xiongyan Wu et al.
ONCOTARGET (2017)
Wanted DEAD/H or Alive: Helicases Winding Up in Cancers
Wanpei Cai et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2017)
Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4
G. Bhuvanalakshmi et al.
FRONTIERS IN PHARMACOLOGY (2017)
PAI-1/PIAS3/Stat3/miR-34a forms a positive feedback loop to promote EMT-mediated metastasis through Stat3 signaling in Non-small cell lung cancer
Xian Lin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
'Lnc'-ing Wnt in female reproductive cancers: therapeutic potential of long non-coding RNAs in Wnt signalling
Mei S. Ong et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
A Flavonoid Glycoside Compound from Murraya paniculata (L.) Interrupts Metastatic Characteristics of A549 Cells by Regulating STAT3/NF-κB/COX-2 and EGFR Signaling Pathways
Qing Shi et al.
AAPS JOURNAL (2017)
Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition
Wei Lou et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2017)
IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis
Li Xu et al.
CANCER LETTERS (2017)
Metformin inhibits castration-induced EMT in prostate cancer by repressing COX2/PGE2/STAT3 axis
Dali Tong et al.
CANCER LETTERS (2017)
TNF-α-inducing protein of Helicobacter pylori induces epithelialmesenchymal transition (EMT) in gastric cancer cells through activation of IL-6/STAT3 signaling pathway
Guodong Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells
Yuan Seng Wu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)
STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression
M. Saitoh et al.
ONCOGENE (2016)
Potential role of targeted therapies in the treatment of triple-negative breast cancer
Lee Yueh Jia et al.
ANTI-CANCER DRUGS (2016)
Annexins A2 and A8 in endothelial cell exocytosis and the control of vascular homeostasis
Volker Gerke
BIOLOGICAL CHEMISTRY (2016)
Epithelial-mesenchymal transition in tissue repair and fibrosis
Rivka C. Stone et al.
CELL AND TISSUE RESEARCH (2016)
WSTF promotes proliferation and invasion of lung cancer cells by inducing EMT via PI3K/Akt and IL-6/STAT3 signaling pathways
Jin Meng et al.
CELLULAR SIGNALLING (2016)
IL-6/STAT3 Plays a Regulatory Role in the Interaction Between Pancreatic Stellate Cells and Cancer Cells
Shin Hamada et al.
DIGESTIVE DISEASES AND SCIENCES (2016)
Inhibition of STAT3 enhances the radiosensitizing effect of temozolomide in glioblastoma cells in vitro and in vivo
Tae Jin Han et al.
JOURNAL OF NEURO-ONCOLOGY (2016)
Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma
Hongfang Zhang et al.
JOURNAL OF RADIATION RESEARCH (2016)
Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma
Xiaoyun Dai et al.
MOLECULAR CANCER THERAPEUTICS (2016)
The biogenesis and emerging roles of circular RNAs
Ling-Ling Chen
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells
Seung Ho Baek et al.
PHYTOMEDICINE (2016)
Potential of neem (Azadirachta indica L.) for prevention and treatment of oncologic diseases
Shradha M. Patel et al.
SEMINARS IN CANCER BIOLOGY (2016)
IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer
Chao Yao et al.
STEM CELLS (2016)
NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer
Suqing Liu et al.
TUMOR BIOLOGY (2016)
Interleukin-32α inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells
Jingfeng Chen et al.
ONCOTARGETS AND THERAPY (2016)
ANXA1 inhibits miRNA-196a in a negative feedback loop through NF-kB and C-Myc to reduce breast cancer proliferation
Yi Yuan et al.
ONCOTARGET (2016)
Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives
Pei Shi Ong et al.
FRONTIERS IN PHARMACOLOGY (2016)
Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5
Indu R. Chandrashekaran et al.
BIOCHEMISTRY (2015)
Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway
Jong Hyun Lee et al.
CANCER LETTERS (2015)
Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer
Kanjoormana A. Manu et al.
CANCER LETTERS (2015)
Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer
Nizam Uddin et al.
CANCER SCIENCE (2015)
Rindopepimut vaccine and bevacizumab combination therapy: improving survival rates in relapsed glioblastoma patients?
Martha R. Neagu et al.
IMMUNOTHERAPY (2015)
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3
Xiaoyun Dai et al.
MOLECULAR ONCOLOGY (2015)
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
Sara Lovisa et al.
NATURE MEDICINE (2015)
Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation
D. Zhao et al.
ONCOGENE (2015)
Primary malignant lymphoma of the uterus and broad ligament: a case report and review of literature
Runzhe Chen et al.
ONCOTARGETS AND THERAPY (2015)
Luteolin decreases invasiveness, deactivates STAT3 signaling, and reverses interleukin-6 induced epithelial-mesenchymal transition and matrix metalloproteinase secretion of pancreatic cancer cells
Xince Huang et al.
ONCOTARGETS AND THERAPY (2015)
Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin
Ying-Min Wu et al.
ONCOTARGET (2015)
MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3
Zhongyi Fan et al.
ONCOTARGET (2015)
Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel
Jong Hyun Lee et al.
ONCOTARGET (2015)
Anxa2 binds to STAT3 and promotes epithelial to mesenchymal transition in breast cancer cells
Tong Wang et al.
ONCOTARGET (2015)
Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop
Zhengyan Yang et al.
ONCOTARGET (2015)
Abrogation of STAT3 Signaling Cascade by Zerumbone Inhibits Proliferation and Induces Apoptosis in Renal Cell Carcinoma Xenograft Mouse Model
Muthu K. Shanmugam et al.
MOLECULAR CARCINOGENESIS (2015)
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K
Daniel J. Ma et al.
NEURO-ONCOLOGY (2015)
Overexpression of ANXA2 predicts adverse outcomes of patients with malignant tumors: a systematic review and meta-analysis
Xinyu Liu et al.
MEDICAL ONCOLOGY (2015)
Multiple regulation pathways and pivotal biological functions of STAT3 in cancer
Jie Yuan et al.
SCIENTIFIC REPORTS (2015)
Diminished Expression of Corticotropin-Releasing Hormone Receptor 2 in Human Colon Cancer Promotes Tumor Growth and Epithelial-to-Mesenchymal Transition via Persistent Interleukin-6/Stat3 Signaling
Jorge A. Rodriguez et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2015)
Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells
K. S. Siveen et al.
BRITISH JOURNAL OF CANCER (2014)
Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells
Sung-Moo Kim et al.
CANCER LETTERS (2014)
Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases
Jong Hyun Lee et al.
CANCER LETTERS (2014)
Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege
Peter E. Fecci et al.
CLINICAL CANCER RESEARCH (2014)
Effect of the STAT3 inhibitor STX-0119 on the proliferation of a temozolomide-resistant glioblastoma cell line
Tadashi Ashizawa et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo
Chakrabhavi Dhananjaya Mohan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice
Kohei Yuyama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Vaccine therapies for patients with glioblastoma
Eli T. Sayegh et al.
JOURNAL OF NEURO-ONCOLOGY (2014)
RRAD Promotes EGFR-Mediated STAT3 Activation and Induces Temozolomide Resistance of Malignant Glioblastoma
Seon-Yong Yeom et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Sphingolipid metabolites in inflammatory disease
Michael Maceyka et al.
NATURE (2014)
Detecting and characterizing circular RNAs
William R. Jeck et al.
NATURE BIOTECHNOLOGY (2014)
Molecular mechanisms of epithelial-mesenchymal transition
Samy Lamouille et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Mark R. Gilbert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Bevacizumab for Newly Diagnosed Glioblastoma Reply
Olivier L. Chinot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
A ROS/STAT3/HIF-1α Signaling Cascade Mediates EGF-Induced TWIST1 Expression and Prostate Cancer Cell Invasion
Kyung Hwa Cho et al.
PROSTATE (2014)
Bevacizumab plus Radiotherapy-Temozolomide for Newly Diagnosed Glioblastoma
Olivier L. Chinot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Cancer Associated Fibroblasts express pro-inflammatory factors in human breast and ovarian tumors
Neta Erez et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
STAT3 mediates TGF-β1-induced TWIST1 expression and prostate cancer invasion
Kyung Hwa Cho et al.
CANCER LETTERS (2013)
Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma
Feng Li et al.
CANCER PREVENTION RESEARCH (2013)
Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation
Kouji Izumi et al.
EMBO MOLECULAR MEDICINE (2013)
Annexin A2 Regulates β1 Integrin Internalization and Intestinal Epithelial Cell Migration
Carl R. Rankin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
HBx-dependent activation of twist mediates STAT3 control of epithelium-mesenchymal transition of liver cells
Jing Teng et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
The epigenetics of epithelial-mesenchymal plasticity in cancer
Wai Leong Tam et al.
NATURE MEDICINE (2013)
Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition
L. Guo et al.
ONCOGENE (2013)
Cancer Stem Cells: Current Status and Evolving Complexities
Jane E. Visvader et al.
CELL STEM CELL (2012)
Targeting EGF receptor variant III: tumor-specific peptide vaccination for malignant gliomas
Catherine A. Del Vecchio et al.
EXPERT REVIEW OF VACCINES (2012)
Hyperactive EGF receptor, Jaks and Stat3 signaling promote enhanced colony-forming ability, motility and migration of cisplatin-resistant ovarian cancer cells
P. Yue et al.
ONCOGENE (2012)
Ursolic Acid Inhibits the Initiation, Progression of Prostate Cancer and Prolongs the Survival of TRAMP Mice by Modulating Pro-Inflammatory Pathways
Muthu K. Shanmugam et al.
PLOS ONE (2012)
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
Xiaolei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Extracellular and intracellular sphingosine-1-phosphate in cancer
Jessie W. Yester et al.
CANCER AND METASTASIS REVIEWS (2011)
The role of the N-terminal domain in dimerization and nucleocytoplasmic shuttling of latent STAT3
Michael Vogt et al.
JOURNAL OF CELL SCIENCE (2011)
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
Taewan Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro
C. Huang et al.
NEOPLASMA (2011)
E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells
Jan Theys et al.
RADIOTHERAPY AND ONCOLOGY (2011)
Signalling pathways in vasculogenic mimicry
Yvette W. J. Paulis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2010)
Bcl-XL and STAT3 mediate malignant actions of γ-irradiation in lung cancer cells
Jin-Nyoung Ho et al.
CANCER SCIENCE (2010)
Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics
Puneet Chopra et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
A. Singh et al.
ONCOGENE (2010)
Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas
M. Colomiere et al.
BRITISH JOURNAL OF CANCER (2009)
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
Marta Paez-Ribes et al.
CANCER CELL (2009)
TGF-β-induced epithelial to mesenchymal transition
Jian Xu et al.
CELL RESEARCH (2009)
Epidermal growth factor-induced ovarian carcinoma cell migration is associated with JAK2/STAT3 signals and changes in the abundance and localization of α6β1 integrin
Michelle Colomiere et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Crystal structure of unphosphorylated STAT3 core fragment
Zhiyong Ren et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Inhibition of STAT3(Tyr705) phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells
Shujie Zhao et al.
CANCER RESEARCH (2008)
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Sun-Mi Park et al.
GENES & DEVELOPMENT (2008)
Structure, function, and regulation of STAT proteins
Cheh Peng Lim et al.
MOLECULAR BIOSYSTEMS (2006)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Real time analysis of STAT3 nucleocytoplasmic shuttling
AL Pranada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Vasculogenic mimicry and tumour-cell plasticity: Lessons from melanoma
MJC Hendrix et al.
NATURE REVIEWS CANCER (2003)
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
J Comijn et al.
MOLECULAR CELL (2001)
分享论文
