期刊
PEDIATRIC BLOOD & CANCER
卷 69, 期 10, 页码 -出版社
WILEY
DOI: 10.1002/pbc.29882
关键词
children; hemangioendothelioma; soft tissue sarcoma; surgery
The European pediatric Soft tissue sarcoma Study Group analyzed children with epithelioid hemangioendothelioma and found that most of them survived after treatment, with high five-year progression-free survival and overall survival rates.
The European pediatric Soft tissue sarcoma Study Group analyzed all children with epithelioid hemangioendothelioma prospectively registered in the NRSTS-05 (EUDRACT 2005-001139-31) and in MTS-2008 (NCT00379457) studies: 10 patients with localized and one with metastatic disease. Median age was 14.3 years (range, 9.0-18.8). Local therapy was initial primary surgery in seven cases, and five patients received systemic therapy. No patients received radiotherapy. After a median follow-up of 50 months (range, 6-176) for living patients, nine patients remain alive off therapy and two died. Five-year progression free and overall survivals are, respectively, 77.1% (95% confidence interval [CI]: 34.5-93.9) and 74.1% (95% CI: 28.1-93.0).
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