Copper-Catalyzed 6-endo-dig Cyclization-Coupling of 2-Bromoaryl Ketones and Terminal Alkynes toward Naphthyl Aryl Ethers in Water

Article Chemistry, Organic

Palladium-Catalyzed Cycloisomerization of 2-Ethynylbiaryls to9-Methylidene Fluorenes

Hongyu Guo et al.

Summary: A palladium-catalyzed cycloisomerization of 2-ethynylbiaryls to 9-methylidenefluorenes is described for the first time. This method is operationally simple and scalable, and exhibits high functional group tolerance.

ORGANIC LETTERS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Asymmetric dearomatization catalysed by chiral Bronsted acids via activation of ynamides

Ying-Qi Zhang et al.

Summary: The use of chiral Bronsted acids in catalytic asymmetric synthesis enables the direct activation of alkynes, leading to the construction of valuable spirocyclic enones and 2H-pyrroles with high yields and excellent enantioselectivity. This activation mode is expected to be widely applicable in catalytic asymmetric reactions involving ynamides and related heteroatom-substituted alkynes.

NATURE CHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Alkyne Trifunctionalization via Divergent Gold Catalysis: Combining π-Acid Activation, Vinyl-Gold Addition, and Redox Catalysis

Teng Yuan et al.

Summary: This study presents a novel method for alkyne trifunctionalization through gold catalysis, achieving consecutive reactions with high efficiency and excellent yields under mild conditions.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cu(i) catalysis for selective condensation/bicycloaromatization of two different arylalkynes: direct and general construction of functionalized C-N axial biaryl compounds

Qian Shang et al.

Summary: The selective condensation/bicycloaromatization of two different arylalkynes was achieved under ligand-free copper (I) catalysis, allowing for the direct synthesis of C-N axial biaryl compounds in high yields with excellent selectivity and functional group tolerance. The use of Cu (I) catalyst and HFIP played critical roles in suppressing undesired reactions and constructing coupled five-six aromatic rings through the selective formation of C(sp(2))-N(sp(2)) bonds and C(sp(2))-C(sp(2)) bonds. This unique reaction has the potential to lead to the simplest asymmetric synthesis of atropoisomeric biaryls, with promising applications in various fields such as biology and pharmaceuticals.

CHEMICAL SCIENCE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Bottom-up modular synthesis of well-defined oligo(arylfuran)s

Yang Chen et al.

Summary: Oligofurans have attracted great attention because of their strong fluorescence, charge delocalization, and increased solubility. Here the authors show a bottom-up modular construction of chemically and structurally well-defined oligo(arylfuran)s by de novo synthesis of alpha, beta '-bifuran monomers and late-stage bromination, stannylation and subsequent coupling reaction.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Copper-Catalyzed Aza-Sonogashira Cross-Coupling To Form Ynimines: Development and Application to the Synthesis of Heterocycles

Remi Lavernhe et al.

Summary: A versatile copper-catalyzed synthesis of ynimines from readily available O-acetyl ketoximes and terminal alkynes has been developed, leading to the synthesis of medicinally important heterocycles.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Photoinduced copper-catalysed asymmetric amidation via ligand cooperativity

Caiyou Chen et al.

Summary: The study describes a method for enantioselective substitution of unactivated alkyl electrophiles using a copper-based photoinduced catalyst system, expanding the scope of enantioselective N-substitution reactions to include unactivated electrophiles.

NATURE (2021)

添加到收藏夹

Article Chemistry, Physical

Nickel-Catalyzed Asymmetric Reductive [3+2] Annulation of o-Haloaromatic β-Alkenyl Ketones with Alkynes via Alkene Isomerization: Enantioselective Synthesis of 1-Alkenyl 1H-Inden-1-ols

Ya-Fei Han et al.

Summary: The nickel-catalyzed asymmetric reductive [3 + 2] annulation of o-haloaromatic beta-alkenyl ketones with alkynes enables the formation of highly enantiomerically enriched compounds with important structural and functional features. This reaction has a broad substrate scope and excellent selectivity, making it suitable for the synthesis of diverse chiral alcohol systems.

ACS CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Organic

CuI-mediated benzannulation of (ortho-arylethynyl)phenylenaminones to assemble α-aminonaphthalene derivatives

Wen-Nian Jiang et al.

Summary: A new synthesis method for a series of structurally diverse α-aminonaphthalene derivatives was developed using a copper-mediated annulation protocol. The resulting compounds were found to have tunable fluorescence properties, as demonstrated by preliminary investigation of their photophysical features.

ORGANIC CHEMISTRY FRONTIERS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mechanistic Study on Gold-Catalyzed Cycloisomerization of Dienediynes Involving Aliphatic C-H Functionalization and Inspiration for Developing a New Strategy to Access Polycarbocycles

Yi Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

NHC-Copper Mediated Ligand-Directed Radiofluorination of Aryl Halides

Liam S. Sharninghausen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bimetallic Catalytic Asymmetric Tandem Reaction of β-Alkynyl Ketones to Synthesize 6,6-Spiroketals

Shulin Ge et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cu(I)-Catalyzed 6-endo-dig Cyclization of Terminal Alkynes, 2-Bromoaryl Ketones, and Amides toward 1-Naphthylamines: Applications and Photophysical Properties

Lebin Su et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Oxalic Diamides and tert-Butoxide: Two Types of Ligands Enabling Practical Access to Alkyl Aryl Ethers via Cu-Catalyzed Coupling Reaction

Zhixiang Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Copper-mediated regioselective C-H etherification of naphthylamides with arylboronic acids using water as an oxygen source

Subhasish Roy et al.

CHEMICAL COMMUNICATIONS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mechanism of the Ullmann Biaryl Ether Synthesis Catalyzed by Complexes of Anionic Ligands: Evidence for the Reaction of Iodoarenes with Ligated Anionic Cu-I Intermediates

Ramesh Giri et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

添加到收藏夹

Article Chemistry, Organic

Copper-Catalyzed Borylative Cyclization of o-(Cyano)phenyl Propargyl Carbonates: Synthesis of Functionalized 1-Naphthylamines

Meijun Xiong et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Transition-Metal-Catalyzed Intramolecular Nucleophilic Addition of Carbonyl Groups to Alkynes

Lianfen Chen et al.

CHEM (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Gold-Catalyzed Oxidative Coupling of Alkynes toward the Synthesis of Cyclic Conjugated Diynes

Xiaohan Ye et al.

CHEM (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Decarbonylative Diaryl Ether Synthesis by Pd and Ni Catalysis

Ryosuke Takise et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

CuI/Oxalamide Catalyzed Couplings of (Hetero)aryl Chlorides and Phenols for Diaryl Ether Formation

Mengyang Fan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

添加到收藏夹

Article Chemistry, Organic

Metal-Free Oxidative Annulation of 2-Naphthols with Terminal Alkynes Affording 2-Arylnaphtho[2,1-b]furans

Long Liu et al.

ORGANIC LETTERS (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development

Carlo Sambiagio et al.

CHEMICAL SOCIETY REVIEWS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Aryl-Copper(III)-Acetylides as Key Intermediates in Csp2-Csp Model Couplings under Mild Conditions

Mireia Rovira et al.

CHEMISTRY-A EUROPEAN JOURNAL (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Mechanistic Insights into Copper-Catalyzed Sonogashira-Hagihara-Type Cross-Coupling Reactions: Sub-Mol% Catalyst Loadings and Ligand Effects

Liang-Hua Zou et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

添加到收藏夹

Article Chemistry, Organic

A New Biarylphosphine Ligand for the Pd-Catalyzed Synthesis of Diaryl Ethers under Mild Conditions

Luca Salvi et al.

ORGANIC LETTERS (2012)

添加到收藏夹

Review Chemistry, Organic

Diaryl Ether Formation in the Synthesis of Natural Products

Emmanuel N. Pitsinos et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2011)

添加到收藏夹

Article Chemistry, Medicinal

The Medicinal Chemist's Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

Stephen D. Roughley et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

添加到收藏夹

Review Chemistry, Organic

Copper-Promoted Carbon-Heteroatom Bond Cross-Coupling with Boronic Acids and Derivatives

Jennifer X. Qiao et al.

SYNTHESIS-STUTTGART (2011)

添加到收藏夹

Review Multidisciplinary Sciences

Carbon-heteroatom bond formation catalysed by organometallic complexes

John F. Hartwig

NATURE (2008)

添加到收藏夹

Article Chemistry, Medicinal

Heteroatom-linked indanylpyrazines are corticotropin releasing factor type-1 receptor antagonists

Jeffrey W. Corbett et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)

添加到收藏夹

Article Chemistry, Multidisciplinary

Significantly improved method for the Pd-catalyzed coupling of phenols with aryl halides: Understanding ligand effects

Carlos H. Burgos et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)

添加到收藏夹

Review Chemistry, Multidisciplinary

Modern synthetic methods for copper-mediated C(aryl)-O, C(aryl)-N, and C(aryl)-S bond formation

SV Ley et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)

添加到收藏夹

Copper-Catalyzed 6-endo-dig Cyclization-Coupling of 2-Bromoaryl Ketones and Terminal Alkynes toward Naphthyl Aryl Ethers in Water

相关参考文献

导出引文

分享论文