相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Safety switches for adoptive cell therapy
Ali Can Sahillioglu et al.
CURRENT OPINION IN IMMUNOLOGY (2022)
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
Louai Labanieh et al.
CELL (2022)
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
Shivani Srivastava et al.
CANCER CELL (2021)
Chimeric antigen receptor T cell therapy in oncology-Pipeline at a glance: Analysis of the ClinicalTrials.gov database
E. Moreno-Cortes et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2021)
The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention
Kerstin Menck et al.
CELLS (2021)
Shaping Functional Avidity of CAR T Cells: Affinity, Avidity, and Antigen Density That Regulate Response
Raanan Greenman et al.
MOLECULAR CANCER THERAPEUTICS (2021)
CAR-T cells: Early successes in blood cancer and challenges in solid tumors
Hassan Dana et al.
ACTA PHARMACEUTICA SINICA B (2021)
Tyrosine Kinase ROR1 as a Target for Anti-Cancer Therapies
Yuming Zhao et al.
FRONTIERS IN ONCOLOGY (2021)
Recent advances and discoveries in the mechanisms and functions of CAR T cells
Rebecca C. Larson et al.
NATURE REVIEWS CANCER (2021)
'Off-the-shelf' allogeneic CAR T cells: development and challenges
S. Depil et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Chemically Programmable and Switchable CAR-T Therapy
Junpeng Qi et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications
Rebecca S. Goydel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Quantitative Control of Gene-Engineered T-Cell Activity through the Covalent Attachment of Targeting Ligands to a Universal Immune Receptor
Nicholas G. Minutolo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Chimeric antigen receptor signaling: Functional consequences and design implications
S. E. Lindner et al.
SCIENCE ADVANCES (2020)
Adaptor CAR Platforms-Next Generation of T Cell-Based Cancer Immunotherapy
Claudia Arndt et al.
CANCERS (2020)
Engineering CAR-T Cells for Next-Generation Cancer Therapy
Mihe Hong et al.
CANCER CELL (2020)
CAR-T design: Elements and their synergistic function
Jayapriya Jayaraman et al.
EBIOMEDICINE (2020)
Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma
Deepak Raj et al.
GUT (2019)
Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
Shivani Srivastava et al.
CANCER CELL (2019)
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
Mohamed-Reda Benmebarek et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Combining the best of two worlds: highly flexible chimeric antigen receptor adaptor molecules (CAR-adaptors) for the recruitment of chimeric antigen receptor T cells
Diana Darowski et al.
MABS (2019)
The Emergence of Universal Immune Receptor T Cell Therapy for Cancer
Nicholas G. Minutolo et al.
FRONTIERS IN ONCOLOGY (2019)
Therapeutic approaches for targeting receptor tyrosine kinase like orphan receptor-1 in cancer cells
Amin Kamrani et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2019)
Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters
Yong Gu Lee et al.
NATURE COMMUNICATIONS (2019)
Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T
Thomas Nerreter et al.
NATURE COMMUNICATIONS (2019)
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR
Sara Ghorashian et al.
NATURE MEDICINE (2019)
A Novel CD19-Anti-CD20 Bridging Protein Prevents and Reverses CD19-Negative Relapse from CAR19 T Cell Treatment In Vivo
Paul Rennert et al.
BLOOD (2019)
Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform
Julian Rydzek et al.
MOLECULAR THERAPY (2019)
An introduction to chimeric antigen receptor (CAR) T-cell immunotherapy for human cancer
Steven Feins et al.
AMERICAN JOURNAL OF HEMATOLOGY (2019)
Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
Jang Hwan Cho et al.
CELL (2018)
Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia
Michael Y. Choi et al.
CELL STEM CELL (2018)
The expansion of targetable biomarkers for CAR T cell therapy
Michelle H. Townsend et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
CAR T cell immunotherapy for human cancer
Carl H. June et al.
SCIENCE (2018)
Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory
Sophie Viaud et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Analysis of ROR1 Protein Expression in Human Cancer and Normal Tissues
Ashwini Balakrishnan et al.
CLINICAL CANCER RESEARCH (2017)
Mining Naive Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility
Haiyong Peng et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer
Yu Cao et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies
David T. Rodgers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Affinity-Tuned ErbB2 or EGFR Chimeric Antigen Receptor T Cells Exhibit an Increased Therapeutic Index against Tumors in Mice
Xiaojun Liu et al.
CANCER RESEARCH (2015)
Designing chimeric antigen receptors to effectively and safely target tumors
Michael C. Jensen et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy
Mahdi Shabani et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2015)
Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
Chia-Yung Wu et al.
SCIENCE (2015)
Economical analysis of saturation mutagenesis experiments
Carlos G. Acevedo-Rocha et al.
SCIENTIFIC REPORTS (2015)
The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
Michael Hudecek et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Safety of Targeting ROR1 in Primates with Chimeric Antigen Receptor-Modified T Cells
Carolina Berger et al.
CANCER IMMUNOLOGY RESEARCH (2015)
The receptor tyrosine kinase ROR1-An oncofetal antigen for targeted cancer therapy
Mohammad Hojjat-Farsangi et al.
SEMINARS IN CANCER BIOLOGY (2014)
Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
Michael Hudecek et al.
CLINICAL CANCER RESEARCH (2013)
How to calculate sample size in animal studies?
Jaykaran Charan et al.
JOURNAL OF PHARMACOLOGY & PHARMACOTHERAPEUTICS (2013)
Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodies
Hema Dave et al.
PLOS ONE (2012)
A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells
Xiuli Wang et al.
BLOOD (2011)
Therapeutic Potential and Challenges of Targeting Receptor Tyrosine Kinase ROR1 with Monoclonal Antibodies in B-Cell Malignancies
Jiahui Yang et al.
PLOS ONE (2011)
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
Michael Hudecek et al.
BLOOD (2010)
Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
Daphne A. Schmid et al.
JOURNAL OF IMMUNOLOGY (2010)
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
V. Hoyos et al.
LEUKEMIA (2010)
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia
Sivasubramanian Baskar et al.
CLINICAL CANCER RESEARCH (2008)
T cell activation by antibody-like immunoreceptors: The position of the binding epitope within the target molecule determines the efficiency of activation of redirected T cells
Andreas A. Hombach et al.
JOURNAL OF IMMUNOLOGY (2007)
Directed in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinity
C Zahnd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
T cell activation by antibody-like immunoreceptors: Increase in affinity of the single-chain fragment domain above threshold does not increase T cell activation against antigen-positive target cells but decreases selectivity
M Chmielewski et al.
JOURNAL OF IMMUNOLOGY (2004)
Design of HIV vectors for efficient gene delivery into human hematopoietic cells
PY Yam et al.
MOLECULAR THERAPY (2002)