Ocular Inflammatory Reactions following an Inactivated SARS-CoV-2 Vaccine: A Four Case Series

Purpose To report a four-case series of ocular adverse events post an inactivated COVID-19 vaccination in China. Methods The four patients exhibited ocular inflammatory reactions on the same day after receiving an inactivated SARS-CoV-2 vaccine. Results All patients underwent detailed ophthalmic examinations, with the medical diagnosis of Vogt-Koyanagi-Harada, Ponser-Schlossman, secondary post-inflammatory glaucoma, and iridocyclitis, respectively. No patients had any other underlying medical conditions causing the ocular complications. The ocular inflammatory reactions of these four patients were resolved with the administration of oral or topical corticosteroids. Conclusion Our cases remind the ophthalmologist that adverse ocular events may happen after the administration of SARS-CoV-2 vaccine. Since the ocular complications could be resolved with the corticosteroid treatment, the events were considered to be inflammatory reactions caused by the SARS-CoV-2 vaccine.

Automated summary

A four-case series of ocular adverse events post inactivated COVID-19 vaccination in China is reported. The ocular inflammatory reactions in these patients were resolved with corticosteroid treatment and were considered to be inflammatory reactions caused by the SARS-CoV-2 vaccine.