☆ 4.7 Editorial Material

Neuroimaging of plasticity mechanisms in the human brain: from critical periods to psychiatric conditions

NEUROPSYCHOPHARMACOLOGY (2023)

A developmental reduction of the excitation:inhibition ratio in association cortex during adolescence

Bart Larsen et al.

Summary: This study used pharmacological fMRI technique to empirically generate a model of E:I ratio based on functional connectivity and investigated the development of the E:I ratio in association cortex during adolescence. The findings revealed a reduction of the E:I ratio in association cortex during adolescence, which was related to psychopathology.

SCIENCE ADVANCES (2022)

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Article Biochemistry & Molecular Biology

Diminished reward responsiveness is associated with lower reward network GluCEST: an ultra-high field glutamate imaging study

Valerie J. Sydnor et al.

Summary: This study provides new evidence that glutamate levels within the reward network contribute to individual differences in reward responsiveness. The association between reward network glutamate levels and reward responsiveness is driven by subcortical regions and areas encoding the salience of valenced stimuli. These findings offer insights into the mechanisms underlying reward network hypofunction and may have implications for the development of treatments for anhedonia.

MOLECULAR PSYCHIATRY (2021)

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Review Neurosciences

Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

Valerie J. Sydnor et al.

Summary: The development of the human brain cortex is a prolonged process that progresses from lower-order functions to higher-order functions, conforming to a hierarchical pattern of organization. This developmental program enhances feature variation between different regions, but also carries risks for diverse developmental psychopathologies.

NEURON (2021)

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Article Multidisciplinary Sciences

Critical period regulation across multiple timescales

Rebecca K. Reh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

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Article Behavioral Sciences

Sensitive periods in human development: charting a course for the future

Laurel Gabard-Durnam et al.

CURRENT OPINION IN BEHAVIORAL SCIENCES (2020)

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Article Neurosciences

Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast

Linn B. Norbom et al.

BIOLOGICAL PSYCHIATRY (2019)

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Neuroimaging of plasticity mechanisms in the human brain: from critical periods to psychiatric conditions

相关参考文献

A developmental reduction of the excitation:inhibition ratio in association cortex during adolescence

Diminished reward responsiveness is associated with lower reward network GluCEST: an ultra-high field glutamate imaging study

Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

Critical period regulation across multiple timescales

Sensitive periods in human development: charting a course for the future

Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast

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