☆ 4.7 Editorial Material

Synaptic plasticity of the orbitofrontal cortex in obesity

NEUROPSYCHOPHARMACOLOGY (2023)

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Summary: The overconsumption of highly palatable, energy-dense food is considered a key driver of the obesity pandemic. This study reveals that obesity disrupts astrocytes in the OFC, leading to a decrease in inhibitory GABA transmission between neurons.

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