期刊
NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY
卷 52, 期 4, 页码 333-338出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.neucli.2022.07.005
关键词
Cognitive Symptoms; Headache-related disability; Migraine Disorders; Pain; tDCS
资金
- Coordination for the Improvement of Higher Education Personnel-CAPES
- Brazilian National Council for Scientific and Technological Development-CNPq [311910/2017-3, 008/2019]
- Pronex, Paraiba State Research Foundation-FAPESQ
- (Beatriz Galindo Programme) in the Department of Psychology at the Universidad de Cordoba [BEAGAL18/00006]
This study compared the effects of different frequencies of transcranial direct current stimulation on chronic migraine patients and found that a once-daily session can significantly decrease migraine-related disability, while a twice-daily session did not show better results.
We compared the effects of one versus two daily sessions of anodal transcranial direct current stimulation (a-tDCS) delivered to the left dorsolateral prefrontal cortex (DLPFC) for 10 days in a cohort of 30 women (mean age 28.0 +/- 6.92) with chronic migraine (CM, disease duration: 37.8 +/- 48.41 month). Participants were randomly allocated to three groups: a-tDCS 1-s Group received one daily a-tDCS session; a-tDCS 2-s Group received two daily a-tDCS sessions; Group SHAM received one daily session with a simulated (placebo) current. All participants were assessed before, after and one month after treatment, using the Migraine Disability Assessment, Montreal Cognitive Assessment, d2 Test of Attention, Trail Making Test (part B), Sequence of Let-ters and Numbers of the Wechsler Adult Intelligence Scale -III, and Nine Hole Peg Test. We found no difference between groups in the cognitive measures and motor dexterity. However, after treatment, a significant decrease in migraine-related disability was found for the a-tDCS 1-s Group. For all variables, no cumulative effects were observed in a-tDCS 2-s compared to the a- tDCS 1-s Group. The study findings provide preliminary results for future clinical trials designed to compare different intervals between tDCS sessions in CM.(c) 2022 Elsevier Masson SAS. All rights reserved.
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