Cracking the combinatorial code of neuronal wiring

How transcription factors orchestrate the combinatorial expression of cell-surface proteins that, in turn, specify the wiring of the nervous system is an open question. In this issue of Neuron, Xie et al. reveal a new, unexpected layer of complexity.

Automated summary

This article investigates the role and regulatory mechanisms of transcription factors in the nervous system, revealing a new level of complexity.