相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
Enquan Xu et al.
MOLECULAR NEURODEGENERATION (2022)
Serum Substance P Is Increased in Parkinson's Disease and Correlates with Motor Impairment
Tommaso Schirinzi et al.
MOVEMENT DISORDERS (2022)
Ten Unsolved Questions About Neuroinflammation in Parkinson's Disease
Etienne C. Hirsch et al.
MOVEMENT DISORDERS (2021)
The Microbiota-Gut-Brain Axis: From Motility to Mood
Kara G. Margolis et al.
GASTROENTEROLOGY (2021)
Increase of Prokineticin-2 in Serum of Patients with Parkinson's Disease
Tommaso Schirinzi et al.
MOVEMENT DISORDERS (2021)
Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease
Sara Konstantin Nissen et al.
MOVEMENT DISORDERS (2021)
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Fangda Leng et al.
NATURE REVIEWS NEUROLOGY (2021)
Lower Lymphocyte Count is Associated With Increased Risk of Parkinson's Disease
Melanie P. Jensen et al.
ANNALS OF NEUROLOGY (2021)
Protein network exploration prioritizes targets for modulating neuroinflammation in Parkinson's disease
Marie-Amandine Bonte et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
Biofluids profile of alpha-Klotho in patients with Parkinson's disease
Giulia Maria Sancesario et al.
PARKINSONISM & RELATED DISORDERS (2021)
Serum and Fecal Markers of Intestinal Inflammation and Intestinal Barrier Permeability Are Elevated in Parkinson's Disease
Laura Dumitrescu et al.
FRONTIERS IN NEUROSCIENCE (2021)
Parkinson's disease and the gastrointestinal microbiome
Michal Lubomski et al.
JOURNAL OF NEUROLOGY (2020)
Systemic activation of Nrf2 pathway in Parkinson's disease
Sara Petrillo et al.
MOVEMENT DISORDERS (2020)
Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's
Fanny M. Elahi et al.
ALZHEIMERS & DEMENTIA (2020)
Differential leukocyte count is associated with clinical phenotype in Parkinson's disease
Tadashi Umehara et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2020)
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease
Cecilia S. Lindestam Arlehamn et al.
NATURE COMMUNICATIONS (2020)
A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study
Riccardo Calvani et al.
GEROSCIENCE (2020)
Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
Max Borsche et al.
BRAIN (2020)
Fractalkine (CX3CL1) signaling and neuroinflammation in Parkinson's disease: Potential clinical and therapeutic implications
Efthalia Angelopoulou et al.
PHARMACOLOGICAL RESEARCH (2020)
Association of inflammatory factors and aging in Parkinson's disease
Hong Jin et al.
NEUROSCIENCE LETTERS (2020)
Inflammation, Infectious Triggers, and Parkinson's Disease
Elisa Caggiu et al.
FRONTIERS IN NEUROLOGY (2019)
Selected serum cytokines and nitric oxide as potential multi-marker biosignature panels for Parkinson disease of varying durations: a case-control study
Dilini Rathnayake et al.
BMC NEUROLOGY (2019)
Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease
Chin-Hsien Lin et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Plasma IL-6 and IL-17A Correlate with Severity of Motor and Non-Motor Symptoms in Parkinson's Disease
Holly F. Green et al.
JOURNAL OF PARKINSONS DISEASE (2019)
Brain-First versus Gut-First Parkinson's Disease: A Hypothesis
Per Borghammer et al.
JOURNAL OF PARKINSONS DISEASE (2019)
High ultrasensitive serum C-reactive protein may be related to freezing of gait in Parkinson's disease patients
Diego Santos-Garcia et al.
JOURNAL OF NEURAL TRANSMISSION (2019)
Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease
Paraskevi Krashia et al.
NATURE COMMUNICATIONS (2019)
Characterization of Parkinson's disease using blood-based biomarkers: A multicohort proteomic analysis
Marijan Posavi et al.
PLOS MEDICINE (2019)
Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice
Paula Perez-Pardo et al.
GUT (2019)
Baseline predictors for progression 4 years after Parkinson's disease diagnosis in the De Novo Parkinson Cohort (DeNoPa)
Brit Mollenhauer et al.
MOVEMENT DISORDERS (2019)
Sexual dimorphism in inflammasome-containing extracellular vesicles and the regulation of innate immunity in the brain of reproductive senescent females
Ami P. Raval et al.
NEUROCHEMISTRY INTERNATIONAL (2019)
Triggers, Facilitators, and Aggravators: Redefining Parkinson's Disease Pathogenesis
Michaela E. Johnson et al.
TRENDS IN NEUROSCIENCES (2019)
Lipopolysaccharide from Gut Microbiota Modulates α-Synuclein Aggregation and Alters Its Biological Function
Dipita Bhattacharyya et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells
Francesca Garretti et al.
FRONTIERS IN IMMUNOLOGY (2019)
Inflammation and fatigue in early, untreated Parkinson's Disease
K. Herlofson et al.
ACTA NEUROLOGICA SCANDINAVICA (2018)
Interleukin-1 beta, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-alpha levels in CSF and serum in relation to the clinical diversity of Parkinson's disease
M. N. Karpenko et al.
CELLULAR IMMUNOLOGY (2018)
Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease
Ashley S. Harms et al.
EXPERIMENTAL NEUROLOGY (2018)
Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis
Vittorio Calabrese et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Abnormalities of age-related T cell senescence in Parkinson's disease
C. H. Williams-Gray et al.
JOURNAL OF NEUROINFLAMMATION (2018)
The Role of Immunosenescence in Neurodegenerative Diseases
Erica Costantini et al.
MEDIATORS OF INFLAMMATION (2018)
Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease
Madelyn C. Houser et al.
MOVEMENT DISORDERS (2018)
Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease
Andreas Schwiertz et al.
PARKINSONISM & RELATED DISORDERS (2018)
Inflammaging: a new immune-metabolic viewpoint for age-related diseases
Claudio Franceschi et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Peripheral blood inflammatory markers in early Parkinson's disease
Ryul Kim et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2018)
The glymphatic pathway in neurological disorders
Martin Kaag Rasmussen et al.
LANCET NEUROLOGY (2018)
Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease
K. Brockmann et al.
EUROPEAN JOURNAL OF NEUROLOGY (2017)
Potential Modes of Intercellular -Synuclein Transmission
Dario Valdinocci et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease
Lori N. Eidson et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over- induction of monocyte- attracting CCL2 by astrocytes
Vincent R. Parillaud et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study
Morten Gersel Stokholm et al.
LANCET NEUROLOGY (2017)
T cells from patients with Parkinson's disease recognize α-synuclein peptides
David Sulzer et al.
NATURE (2017)
GENOME-WIDE PATHWAY-BASED ASSOCIATION ANALYSIS IDENTIFIES RISK PATHWAYS ASSOCIATED WITH PARKINSON'S DISEASE
Mingming Zhang et al.
NEUROSCIENCE (2017)
Should We Stop Saying 'Glia' and 'Neuroinflammation'?
Roser Masgrau et al.
TRENDS IN MOLECULAR MEDICINE (2017)
Increased Levels of Pro-Inflammatory and Anti-Inflammatory Cellular Responses in Parkinson's Disease Patients: Search for a Disease Indicator
Likun Yang et al.
MEDICAL SCIENCE MONITOR (2017)
Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease
Alexa R. Weingarden et al.
GUT MICROBES (2017)
Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes
Corinna Bliederhaeuser et al.
ACTA NEUROPATHOLOGICA (2016)
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease
Timothy R. Sampson et al.
CELL (2016)
IL-6 serum levels are elevated in Parkinson's disease patients with fatigue compared to patients without fatigue
Jessica Ramos Pereira et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2016)
Increased Peripheral Inflammation in Asymptomatic Leucine-Rich Repeat Kinase 2 Mutation Carriers
Nicolas Dzamko et al.
MOVEMENT DISORDERS (2016)
Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD)
Caroline H. Williams-Gray et al.
MOVEMENT DISORDERS (2016)
Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls
Marcus M. Unger et al.
PARKINSONISM & RELATED DISORDERS (2016)
Aberrations in Peripheral Inflammatory Cytokine Levels in Parkinson Disease A Systematic Review and Meta-analysis
Xiao-Yan Qin et al.
JAMA NEUROLOGY (2016)
Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans
Shu G. Chen et al.
SCIENTIFIC REPORTS (2016)
Colonic Bacterial Composition in Parkinson's Disease
Ali Keshavarzian et al.
MOVEMENT DISORDERS (2015)
Parkinson disease with REM sleep behavior disorder Features, α-synuclein, and inflammation
Yang Hu et al.
NEUROLOGY (2015)
Increased CSF biomarkers of angiogenesis in Parkinson disease
Shorena Janelidze et al.
NEUROLOGY (2015)
Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease
YaXing Gui et al.
ONCOTARGET (2015)
Gut Microbiota Are Related to Parkinson's Disease and Clinical Phenotype
Filip Scheperjans et al.
MOVEMENT DISORDERS (2015)
Baseline C-Reactive Protein Levels and Life Prognosis in Parkinson Disease
Hideyuki Sawada et al.
PLOS ONE (2015)
Intestinal Dysbiosis and Lowered Serum Lipopolysaccharide-Binding Protein in Parkinson's Disease
Satoru Hasegawa et al.
PLOS ONE (2015)
Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson's disease: an observational and case-control study
G. T. Kannarkat et al.
NPJ PARKINSONS DISEASE (2015)
Potential biomarkers relating pathological proteins, neuroinflammatory factors and free radicals in PD patients with cognitive impairment: a cross-sectional study
Shu-yang Yu et al.
BMC NEUROLOGY (2014)
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease
Carmen Noelker et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
William T. Wissemann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinsons disease
Peter Holmans et al.
HUMAN MOLECULAR GENETICS (2013)
MHCII Is Required for α-Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneratione
Ashley S. Harms et al.
JOURNAL OF NEUROSCIENCE (2013)
Inflammation and α-Synuclein's Prion-like Behavior in Parkinson's Disease-Is There a Link?
Carla M. Lema Tome et al.
MOLECULAR NEUROBIOLOGY (2013)
Elevated Alpha-Synuclein Impairs Innate Immune Cell Function and Provides a Potential Peripheral Biomarker for Parkinson's Disease
Shyra J. Gardai et al.
PLOS ONE (2013)
Genomic responses in mouse models poorly mimic human inflammatory diseases
Junhee Seok et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
Carmen Noelker et al.
SCIENTIFIC REPORTS (2013)
Clinical and Biochemical Differences in Patients Having Parkinson Disease With vs Without GBA Mutations
Lama M. Chahine et al.
JAMA NEUROLOGY (2013)
Increased Intestinal Permeability and Parkinson Disease Patients: Chicken or Egg?
D. Salat-Foix et al.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2012)
On communication between gut microbes and the brain
Paul Forsythe et al.
CURRENT OPINION IN GASTROENTEROLOGY (2012)
CD4+Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson's Disease
Jessica A. Hutter Saunders et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)
Impact of L-DOPA treatment on regional cerebral blood flow and metabolism in the basal ganglia in a rat model of Parkinson's disease
K. Elisabet Ohlin et al.
NEUROIMAGE (2012)
Host-Gut Microbiota Metabolic Interactions
Jeremy K. Nicholson et al.
SCIENCE (2012)
Cerebrospinal Fluid Biomarkers for Parkinson Disease Diagnosis and Progression
Min Shi et al.
ANNALS OF NEUROLOGY (2011)
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
Michael A. Nalls et al.
LANCET (2011)
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
Marco Prinz et al.
NATURE NEUROSCIENCE (2011)
Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease
Christopher B. Forsyth et al.
PLOS ONE (2011)
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism
Francisco Ros-Bernal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Nitrated α-Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets
Ashley D. Reynolds et al.
JOURNAL OF IMMUNOLOGY (2009)
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C. Hirsch et al.
LANCET NEUROLOGY (2009)
Synuclein activates microglia in a model of Parkinson's disease
Xiaomin Su et al.
NEUROBIOLOGY OF AGING (2008)
Nitrated α-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
Eric J. Benner et al.
PLOS ONE (2008)
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease
Ashley D. Reynolds et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Peripheral inflammatory biomarkers and risk of Parkinson's disease
Honglei Chen et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2008)
Circulating interleukin-15 and RANTES chemokine in Parkinson's disease
M. Rentzos et al.
ACTA NEUROLOGICA SCANDINAVICA (2007)
Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo
R Kortekaas et al.
ANNALS OF NEUROLOGY (2005)
Changes in vascularization in substantia nigra pars compacta of monkeys rendered parkinsonian
C Barcia et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)