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Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin
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Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release
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Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system
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Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats
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BEHAVIOURAL BRAIN RESEARCH (2010)
TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation
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Ca2+-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate
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TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
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Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
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TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
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NATURE MEDICINE (2008)
TRPV1 shows dynamic ionic selectivity during agonist stimulation
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NATURE NEUROSCIENCE (2008)
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NATURE NEUROSCIENCE (2008)
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
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JOURNAL OF NEUROSCIENCE (2007)
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JOURNAL OF PHYSIOLOGY-LONDON (2007)
Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury
J. Frederick et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The menthol receptor TRPM8 is the principal detector of environmental cold
Diana M. Bautista et al.
NATURE (2007)
Dual regulation of TRPV1 by phosphoinositides
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JOURNAL OF NEUROSCIENCE (2007)
Dissection of the components for PIP2 activation and thermosensation in TRP channels
Sebastian Brauchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
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BMC NEUROLOGY (2007)
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
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EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
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NATURE (2007)
Nitric oxide activates TRP channels by cysteine S-nitrosylation
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NATURE CHEMICAL BIOLOGY (2006)
TRPV1: a therapeutic target for novel analgesic drugs?
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Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
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Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain
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Potentiation of TRPV3 channel function by unsaturated fatty acids
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TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
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Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG
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Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
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Ca2+/calmodulin modulates TRPV1 activation by capsaicin
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JOURNAL OF GENERAL PHYSIOLOGY (2004)
TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH
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A newly identified role for superoxide in inflammatory pain
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Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat
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Hypotonicity induces TRPV4-mediated nociception in rat
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Structural determinant of TRPV1 desensitization interacts with calmodulin
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
GM Story et al.
CELL (2003)
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
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A heat-sensitive TRP channel expressed in keratinocytes
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A TRP channel that senses cold stimuli and menthol
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Identification of a cold receptor reveals a general role for TRP channels in thermosensation
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NATURE (2002)
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
AL Perraud et al.
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