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NATURE NEUROSCIENCE (2015)
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MOLECULAR PHARMACOLOGY (2014)
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Emerging roles of TRPA1 in sensation of oxidative stress and its implications in defense and danger
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ARCHIVES OF PHARMACAL RESEARCH (2013)
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BRITISH JOURNAL OF PHARMACOLOGY (2013)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
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Structure of the TRPV1 ion channel determined by electron cryo-microscopy
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NATURE (2013)
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NATURE REVIEWS NEUROSCIENCE (2013)
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
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PAIN (2013)
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PAIN (2013)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Species differences and molecular determinant of TRPA1 cold sensitivity
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NATURE COMMUNICATIONS (2013)
Flavanones That Selectively Inhibit TRPM3 Attenuate Thermal Nociception In Vivo
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MOLECULAR PHARMACOLOGY (2013)
Agonist- and Ca2+-dependent Desensitization of TRPV1 Channel Targets the Receptor to Lysosomes for Degradation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
TRPM2 Contributes to Inflammatory and Neuropathic Pain through the Aggravation of Pronociceptive Inflammatory Responses in Mice
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Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site
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NATURE CHEMICAL BIOLOGY (2012)
Central Mechanisms of Menthol-Induced Analgesia
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Localization of the PIP2 Sensor of TRPV1 Ion Channels
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Hysteresis of gating underlines sensitization of TRPV3 channels
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JOURNAL OF GENERAL PHYSIOLOGY (2011)
TRPV3 and TRPV4 ion channels are not major contributors to mouse heat sensation
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MOLECULAR PAIN (2011)
TRPM3 Is a Nociceptor Channel Involved in the Detection of Noxious Heat
Joris Vriens et al.
NEURON (2011)
Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin
Matthias A. Engel et al.
NEUROPEPTIDES (2011)
Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release
June Yowtak et al.
PAIN (2011)
Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system
Katharina Zimmermann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
Takashi Miyamoto et al.
NATURE COMMUNICATIONS (2011)
Wallerian Degeneration, Wld(S), and Nmnat
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ANNUAL REVIEW OF NEUROSCIENCE, VOL 33 (2010)
Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats
Amanda H. Klein et al.
BEHAVIOURAL BRAIN RESEARCH (2010)
TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation
Xiping Cheng et al.
CELL (2010)
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
Christopher J. Bohlen et al.
CELL (2010)
Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath
Valeria Tekus et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
Ca2+-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate
Jose Mercado et al.
JOURNAL OF NEUROSCIENCE (2010)
TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats
Steve McGaraughty et al.
MOLECULAR PAIN (2010)
New familial pain syndrome caused by TRPA1 mutation
Heather Wood
Nature Reviews Neurology (2010)
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
Barbara Kremeyer et al.
NEURON (2010)
Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat
Hong Wei et al.
NEUROPHARMACOLOGY (2010)
TRPV1: On the Road to Pain Relief
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Current Molecular Pharmacology (2010)
Inhibition of TRPM8 by Icilin Distinct from Desensitization Induced by Menthol and Menthol Derivatives
Frank J. P. Kuehn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
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JOURNAL OF PAIN (2009)
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NATURE REVIEWS DRUG DISCOVERY (2009)
Activation of transient receptor potential ankyrin 1 by hydrogen peroxide
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EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
Selective role for TRPV4 ion channels in visceral sensory pathways
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GASTROENTEROLOGY (2008)
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Rebecca M. Klein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes
Ben Buelow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions
Yuanyuan Y. Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2
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JOURNAL OF NEUROSCIENCE (2008)
TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
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JOURNAL OF NEUROSCIENCE (2008)
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
Shinichiro Yamamoto et al.
NATURE MEDICINE (2008)
TRPV1 shows dynamic ionic selectivity during agonist stimulation
Man-Kyo Chung et al.
NATURE NEUROSCIENCE (2008)
A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
Hector Salazar et al.
NATURE NEUROSCIENCE (2008)
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition
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MOLECULAR PAIN (2007)
TRPM8 mechanism of cold allodynia after chronic nerve injury
Hong Xing et al.
JOURNAL OF NEUROSCIENCE (2007)
Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization
Armen N. Akopian et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury
J. Frederick et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The menthol receptor TRPM8 is the principal detector of environmental cold
Diana M. Bautista et al.
NATURE (2007)
Dual regulation of TRPV1 by phosphoinositides
Viktor Lukacs et al.
JOURNAL OF NEUROSCIENCE (2007)
Dissection of the components for PIP2 activation and thermosensation in TRP channels
Sebastian Brauchi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
Paul Facer et al.
BMC NEUROLOGY (2007)
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
Barbara Costa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
Lindsey J. Macpherson et al.
NATURE (2007)
Nitric oxide activates TRP channels by cysteine S-nitrosylation
Takashi Yoshida et al.
NATURE CHEMICAL BIOLOGY (2006)
TRPV1: a therapeutic target for novel analgesic drugs?
Arpad Szallasi et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
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JOURNAL OF GENERAL PHYSIOLOGY (2006)
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain
Clare J. Proudfoot et al.
CURRENT BIOLOGY (2006)
Potentiation of TRPV3 channel function by unsaturated fatty acids
Hong-Zhen Hu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
DM Bautista et al.
CELL (2006)
Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG
G Shimosato et al.
PAIN (2005)
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
JAM Coull et al.
NATURE (2005)
Desensitization of canonical transient receptor potential channel 5 by protein kinase C
MH Zhu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
The pungency of garlic: Activation of TRPA1 and TRPV1 in response to allicin
LJ Macpherson et al.
CURRENT BIOLOGY (2005)
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
M Kolisek et al.
MOLECULAR CELL (2005)
Ca2+/calmodulin modulates TRPV1 activation by capsaicin
T Rosenbaum et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH
DA Andersson et al.
JOURNAL OF NEUROSCIENCE (2004)
A newly identified role for superoxide in inflammatory pain
ZQ Wang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Transient receptor potential vanilloid 4 is essential in chemotherapy-induced neuropathic pain in the rat
N Alessandri-Haber et al.
JOURNAL OF NEUROSCIENCE (2004)
Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats
MR Zahner et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Hypotonicity induces TRPV4-mediated nociception in rat
N Alessandri-Haber et al.
NEURON (2003)
Structural determinant of TRPV1 desensitization interacts with calmodulin
M Numazaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
GM Story et al.
CELL (2003)
TRPV3 is a temperature-sensitive vanilloid receptor-like protein
GD Smith et al.
NATURE (2002)
A heat-sensitive TRP channel expressed in keratinocytes
AM Peier et al.
SCIENCE (2002)
Menthol: a natural analgesic compound
N Galeotti et al.
NEUROSCIENCE LETTERS (2002)
A TRP channel that senses cold stimuli and menthol
AM Peier et al.
CELL (2002)
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
DD McKemy et al.
NATURE (2002)
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
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Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
W Liedtke et al.
CELL (2000)
Acid potentiation of the capsaicin receptor determined by a key extracellular site
SE Jordt et al.
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Hyperalgesia due to nerve injury: Role of neutrophils
NM Perkins et al.
NEUROSCIENCE (2000)
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