Long life depends on open communication

Y The lysosome is an essential organelle that degrades extra- and intra-cellular components and acts as a signaling hub. A study in Caenorhabditis elegans now shows that the lysosome mediates inter-tissue communication from periphery to neurons to regulate lifespan via fatty acid breakdown and secretion.

Automated summary

The lysosome plays a crucial role in regulating lifespan by mediating inter-tissue communication through fatty acid breakdown and secretion in Caenorhabditis elegans.